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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:277.5 nTPM
HPA:277.5 nTPM
GTEx:210.0 nTPM
FANTOM5:283.4 Scaled Tags Per Million
Pig:59.8 nTPM
Mouse:54.9 nTPM
Allen mouse:1.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 277.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 229.3
1830 Male, age 51, unknown 263.0
2666 Male, age 74, left hemisphere 255.9
1833 Male, age 53, unknown 255.7
2411 Female, age 72, unknown 238.7
2586 Male, age 75, left hemisphere 233.0
2019 Male, age 18, unknown 227.3
1870 Female, age 42, unknown 221.9
2828 Female, age 72, unknown 214.7
2219 Male, age 76, both hemispheres 201.6
1827 Male, age 72, unknown 181.7
Dorsal raphe nucleus
nTPM: 180.1
2750 Male, age 76, both hemispheres 237.8
2016 Female, age 72, unknown 192.5
1828 Male, age 53, unknown 176.1
2047 Male, age 72, unknown 150.4
2298 Female, age 72, unknown 143.7
Inferior colliculus
nTPM: 178.4
2849 Male, age 72, unknown 186.2
1890 Male, age 53, unknown 183.7
1848 Female, age 42, unknown 182.1
2097 Female, age 72, unknown 161.3
Median raphe nucleus
nTPM: 160.6
2220 Male, age 76, midline 160.6
Pedunculopontine tegmental nucleus
nTPM: 201.2
2334 Male, age 80, both hemispheres 212.8
2338 Male, age 61, both hemispheres 202.3
1921 Female, age 85, both hemispheres 188.6
Periaquaductal grey, anterior
nTPM: 181.3
1947 Male, age 18, unknown 195.2
2502 Female, age 75, unknown 190.5
1795 Male, age 51, unknown 158.4
Periaquaductal grey, dorsal
nTPM: 158.0
2464 Female, age 72, unknown 193.7
1831 Male, age 72, unknown 161.8
1840 Male, age 53, unknown 139.9
2850 Male, age 76, both hemispheres 136.8
Periaquaductal grey, lateral
nTPM: 151.8
2053 Male, age 18, unknown 161.2
2272 Male, age 74, both hemispheres 157.6
2140 Male, age 76, both hemispheres 136.6
Pretectal area
nTPM: 176.7
1815 Male, age 53, unknown 229.6
2316 Male, age 76, right hemisphere 204.4
1817 Female, age 42, unknown 200.2
2007 Male, age 72, unknown 192.2
2407 Male, age 75, both hemispheres 184.2
2825 Male, age 18, unknown 178.6
1816 Male, age 51, unknown 159.6
2224 Female, age 72, unknown 151.7
2667 Female, age 75, unknown 150.7
1944 Female, age 72, unknown 149.6
2273 Male, age 74, both hemispheres 142.7
Red nucleus
nTPM: 277.5
1904 Male, age 53, unknown 323.5
1865 Male, age 51, unknown 311.5
2503 Female, age 72, unknown 306.4
2588 Male, age 74, left hemisphere 301.9
1821 Female, age 72, unknown 292.0
2769 Male, age 72, unknown 280.1
2227 Male, age 72, unknown 277.3
2823 Male, age 76, right hemisphere 269.3
2785 Male, age 18, unknown 265.3
1954 Female, age 42, unknown 262.6
2725 Female, age 75, unknown 234.8
2584 Male, age 75, left hemisphere 205.0
Substantia nigra
nTPM: 190.7
2409 Female, age 72, unknown 217.5
2590 Female, age 75, unknown 206.8
1889 Female, age 72, unknown 203.5
2665 Male, age 74, both hemispheres 201.5
1851 Male, age 51, unknown 198.0
2583 Male, age 75, right hemisphere 191.9
2699 Male, age 18, unknown 183.3
2241 Male, age 72, unknown 178.5
1941 Male, age 53, unknown 166.3
1916 Female, age 42, unknown 159.6
Superior colliculus
nTPM: 209.3
1995 Male, age 72, unknown 255.2
2668 Female, age 75, unknown 240.7
1895 Male, age 76, right hemisphere 236.2
1913 Female, age 42, unknown 228.8
2587 Male, age 74, left hemisphere 220.8
1839 Male, age 51, unknown 211.3
2664 Male, age 75, both hemispheres 184.3
1796 Male, age 53, unknown 179.2
2261 Male, age 18, unknown 173.2
2087 Female, age 72, unknown 162.9
Ventral tegmental area
nTPM: 191.5
2410 Female, age 72, unknown 234.7
2223 Female, age 72, unknown 215.8
1942 Male, age 51, unknown 180.1
1915 Female, age 42, unknown 178.3
2218 Male, age 76, both hemispheres 172.8
2021 Male, age 53, unknown 167.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 210.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 210.0
Samples: 139

Max nTPM: 588.9
Min nTPM: 38.7
Std nTPM: 118.8
Median nTPM: 183.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 588.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 585.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 513.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 472.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 472.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 471.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 451.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 448.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 442.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 429.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 424.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 414.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 412.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 372.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 372.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 364.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 362.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 358.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 354.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 352.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 349.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 340.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 331.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 324.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 323.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 311.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 311.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 292.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 292.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 291.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 289.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 288.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 284.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 279.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 277.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 270.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 270.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 266.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 263.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 262.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 257.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 255.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 249.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 243.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 241.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 240.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 237.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 234.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 233.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 233.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 230.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 228.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 228.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 227.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 223.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 220.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 219.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 215.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 207.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 201.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 199.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 199.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 197.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 196.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 194.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 193.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 190.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 188.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 187.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 183.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 182.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 181.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 179.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 174.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 171.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 166.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 166.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 163.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 161.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 160.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 160.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 159.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 158.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 154.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 152.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 151.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 150.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 148.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 146.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 139.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 136.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 136.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 134.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 132.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 130.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 128.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 126.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 126.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 124.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 116.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 116.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 115.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 115.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 114.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 113.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 112.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 111.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 110.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 108.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 108.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 106.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 105.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 104.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 104.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 102.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 100.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 99.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 98.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 97.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 95.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 94.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 91.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 89.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 88.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 88.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 85.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 84.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 79.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 79.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 71.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 71.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 66.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 63.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 62.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 60.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 58.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 53.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 47.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 38.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 283.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 283.4
FF:10158-103A5 76 years, female 283.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 59.8
Pig sample Sample description nTPM
Midbrain
nTPM: 59.8
Samples: 4

Max nTPM: 117.7
Min nTPM: 31.3
Sample A Female 117.7
Sample B Female 55.5
Sample C Male 31.3
Sample D Male 34.5
Periaqueductal gray
nTPM: 39.4
Samples: 3

Max nTPM: 45.4
Min nTPM: 29.2
Sample B Female 45.4
Sample C Male 29.2
Sample D Male 43.5
Substantia nigra
nTPM: 59.1
Samples: 4

Max nTPM: 90.1
Min nTPM: 42.9
Sample A Female 56.0
Sample B Female 42.9
Sample C Male 47.5
Sample D Male 90.1
Superior colliculi
nTPM: 49.3
Samples: 4

Max nTPM: 52.8
Min nTPM: 44.5
Sample A Female 50.9
Sample B Female 49.0
Sample C Male 44.5
Sample D Male 52.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.9
Samples: 4

Max nTPM: 57.4
Min nTPM: 53.1
Sample A Male 53.2
Sample B Male 53.1
Sample C Female 56.0
Sample D Female 57.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.0
75749420 Antisense, RP_060518_04_E04, Mouse strain C57BL/6J (56 days, male) 1.2
79556595 Antisense, RP_071018_01_G09, Mouse strain C57BL/6J (56 days, male) 0.8
79360278 Antisense, RP_071018_01_G09, Mouse strain C57BL/6J (56 days, male) 0.7

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