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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:115346.3 nTPM
HPA:115346.3 nTPM
GTEx:132538.5 nTPM
Pig:55324.6 nTPM
Mouse:30853.7 nTPM
Allen mouse:22.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 115346.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 109705.7
2586 Male, age 75, left hemisphere 123929.7
2219 Male, age 76, both hemispheres 121871.5
2828 Female, age 72, unknown 115417.8
2666 Male, age 74, left hemisphere 113271.2
1833 Male, age 53, unknown 108948.9
1870 Female, age 42, unknown 107590.2
1830 Male, age 51, unknown 106431.5
2019 Male, age 18, unknown 103060.2
1827 Male, age 72, unknown 100787.0
2411 Female, age 72, unknown 95748.9
Dorsal raphe nucleus
nTPM: 100401.0
1828 Male, age 53, unknown 108115.2
2047 Male, age 72, unknown 102526.6
2750 Male, age 76, both hemispheres 100966.7
2016 Female, age 72, unknown 98563.0
2298 Female, age 72, unknown 91833.7
Inferior colliculus
nTPM: 105825.9
2849 Male, age 72, unknown 115718.0
1890 Male, age 53, unknown 108283.1
1848 Female, age 42, unknown 103686.5
2097 Female, age 72, unknown 95616.2
Median raphe nucleus
nTPM: 115346.3
2220 Male, age 76, midline 115346.3
Pedunculopontine tegmental nucleus
nTPM: 106454.3
2334 Male, age 80, both hemispheres 113436.3
2338 Male, age 61, both hemispheres 106536.2
1921 Female, age 85, both hemispheres 99390.3
Periaquaductal grey, anterior
nTPM: 100205.2
2502 Female, age 75, unknown 103536.7
1795 Male, age 51, unknown 98972.8
1947 Male, age 18, unknown 98106.2
Periaquaductal grey, dorsal
nTPM: 103271.0
2850 Male, age 76, both hemispheres 114082.4
1831 Male, age 72, unknown 102209.3
2464 Female, age 72, unknown 99228.4
1840 Male, age 53, unknown 97564.1
Periaquaductal grey, lateral
nTPM: 98098.3
2140 Male, age 76, both hemispheres 100024.2
2053 Male, age 18, unknown 100023.9
2272 Male, age 74, both hemispheres 94246.8
Pretectal area
nTPM: 106690.2
1944 Female, age 72, unknown 118192.8
1817 Female, age 42, unknown 117547.9
1816 Male, age 51, unknown 116677.7
2667 Female, age 75, unknown 115872.2
1815 Male, age 53, unknown 111059.3
2007 Male, age 72, unknown 110507.8
2825 Male, age 18, unknown 103298.2
2407 Male, age 75, both hemispheres 98851.1
2224 Female, age 72, unknown 95377.4
2316 Male, age 76, right hemisphere 93333.0
2273 Male, age 74, both hemispheres 92874.6
Red nucleus
nTPM: 109369.0
2588 Male, age 74, left hemisphere 116116.4
2503 Female, age 72, unknown 114567.5
2584 Male, age 75, left hemisphere 112167.0
1954 Female, age 42, unknown 111702.1
2823 Male, age 76, right hemisphere 111267.2
2785 Male, age 18, unknown 110976.3
1865 Male, age 51, unknown 110226.5
2227 Male, age 72, unknown 106878.7
2769 Male, age 72, unknown 106184.4
1904 Male, age 53, unknown 105865.7
1821 Female, age 72, unknown 103307.0
2725 Female, age 75, unknown 103169.0
Substantia nigra
nTPM: 112766.2
2665 Male, age 74, both hemispheres 148173.7
2699 Male, age 18, unknown 122410.7
1916 Female, age 42, unknown 117484.9
1889 Female, age 72, unknown 111424.1
1941 Male, age 53, unknown 107944.9
2583 Male, age 75, right hemisphere 106989.1
2241 Male, age 72, unknown 105503.3
1851 Male, age 51, unknown 103361.5
2409 Female, age 72, unknown 102250.9
2590 Female, age 75, unknown 102118.6
Superior colliculus
nTPM: 104756.4
2664 Male, age 75, both hemispheres 114476.7
2087 Female, age 72, unknown 110742.1
2587 Male, age 74, left hemisphere 106709.1
1913 Female, age 42, unknown 104988.9
2668 Female, age 75, unknown 103846.4
1839 Male, age 51, unknown 102082.7
1895 Male, age 76, right hemisphere 101739.8
1995 Male, age 72, unknown 101616.2
2261 Male, age 18, unknown 100701.9
1796 Male, age 53, unknown 100659.7
Ventral tegmental area
nTPM: 106269.7
2218 Male, age 76, both hemispheres 116889.2
2223 Female, age 72, unknown 108129.9
1942 Male, age 51, unknown 106357.4
1915 Female, age 42, unknown 104114.9
2410 Female, age 72, unknown 101069.0
2021 Male, age 53, unknown 101057.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 132538.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 132538.5
Samples: 139

Max nTPM: 435093.3
Min nTPM: 19971.6
Std nTPM: 81032.8
Median nTPM: 104262.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 435093.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 425248.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 397242.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 351134.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 346770.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 284070.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 283243.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 282589.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 270728.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 266531.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 265441.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 259827.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 256640.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 252097.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 247521.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 245578.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 244063.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 238409.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 234608.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 234190.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 227085.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 220822.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 218300.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 203372.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 203176.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 201594.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 199434.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 194812.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 192062.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 191634.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 183616.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 171688.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 168760.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 168276.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 161095.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 159812.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 156400.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 155418.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 151256.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 151176.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 149822.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 149338.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 148413.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 144861.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 142913.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 141442.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 138959.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 136428.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 134585.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 133732.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 132453.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 128661.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 128583.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 127644.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 126993.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 126858.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126480.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 124912.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 124451.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 122647.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 119217.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 115089.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 111805.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 111768.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 110054.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 107239.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 105873.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 105788.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 105752.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 104262.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 104115.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 103863.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 103784.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 102776.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 102261.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 101378.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 101107.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 100875.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 100727.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 99810.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 99596.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 98377.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 96543.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 94616.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 94147.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94093.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 92020.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 91593.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 90751.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 89120.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 86735.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 86553.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85169.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 83607.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 83471.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 81642.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 81024.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 80340.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 80140.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 79535.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 79327.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 79324.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 76757.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 75315.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 74800.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 74284.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 72257.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 72142.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 72019.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 71254.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 71091.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 70876.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 70543.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 70323.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 69797.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 68266.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 68114.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 65448.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 63594.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62794.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 60498.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 60159.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 58356.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 58126.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 57181.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 55729.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 54496.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 54110.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53640.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 52799.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 47491.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 46835.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46655.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 42921.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 42294.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 36485.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 35831.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 33290.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 19971.6
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55324.6
Pig sample Sample description nTPM
Midbrain
nTPM: 55324.6
Samples: 4

Max nTPM: 69977.4
Min nTPM: 41916.2
Sample A Female 41916.2
Sample B Female 69977.4
Sample C Male 63677.6
Sample D Male 45727.2
Periaqueductal gray
nTPM: 38264.8
Samples: 3

Max nTPM: 41181.1
Min nTPM: 33002.0
Sample B Female 40611.3
Sample C Male 41181.1
Sample D Male 33002.0
Substantia nigra
nTPM: 46051.5
Samples: 4

Max nTPM: 64631.2
Min nTPM: 29966.4
Sample A Female 64631.2
Sample B Female 38590.9
Sample C Male 51017.5
Sample D Male 29966.4
Superior colliculi
nTPM: 50619.4
Samples: 4

Max nTPM: 68452.8
Min nTPM: 20027.6
Sample A Female 59887.7
Sample B Female 20027.6
Sample C Male 68452.8
Sample D Male 54109.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30853.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 30853.7
Samples: 4

Max nTPM: 31933.1
Min nTPM: 29793.2
Sample A Male 31933.1
Sample B Male 30088.4
Sample C Female 31600.2
Sample D Female 29793.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 22.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 22.1
74357773 Antisense, RP_051219_04_A07, Mouse strain C57BL/6J (56 days, male) 22.1

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