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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:38.8 nTPM
HPA:38.8 nTPM
GTEx:47.3 nTPM
FANTOM5:139.2 Scaled Tags Per Million
Pig:32.2 nTPM
Mouse:17.3 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 38.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 31.4
1870 Female, age 42, unknown 34.6
2411 Female, age 72, unknown 34.6
2019 Male, age 18, unknown 33.9
1830 Male, age 51, unknown 33.7
1833 Male, age 53, unknown 33.2
2828 Female, age 72, unknown 32.7
2586 Male, age 75, left hemisphere 30.7
1827 Male, age 72, unknown 27.8
2219 Male, age 76, both hemispheres 27.2
2666 Male, age 74, left hemisphere 25.6
Dorsal raphe nucleus
nTPM: 34.3
2016 Female, age 72, unknown 40.7
1828 Male, age 53, unknown 36.7
2298 Female, age 72, unknown 33.3
2750 Male, age 76, both hemispheres 32.9
2047 Male, age 72, unknown 28.0
Inferior colliculus
nTPM: 31.6
1890 Male, age 53, unknown 34.4
2097 Female, age 72, unknown 33.9
2849 Male, age 72, unknown 30.3
1848 Female, age 42, unknown 27.7
Median raphe nucleus
nTPM: 23.8
2220 Male, age 76, midline 23.8
Pedunculopontine tegmental nucleus
nTPM: 30.3
2334 Male, age 80, both hemispheres 33.7
1921 Female, age 85, both hemispheres 30.4
2338 Male, age 61, both hemispheres 26.7
Periaquaductal grey, anterior
nTPM: 33.1
2502 Female, age 75, unknown 40.6
1795 Male, age 51, unknown 30.8
1947 Male, age 18, unknown 27.9
Periaquaductal grey, dorsal
nTPM: 38.8
2850 Male, age 76, both hemispheres 44.3
1840 Male, age 53, unknown 42.2
2464 Female, age 72, unknown 35.7
1831 Male, age 72, unknown 33.1
Periaquaductal grey, lateral
nTPM: 37.0
2140 Male, age 76, both hemispheres 41.1
2053 Male, age 18, unknown 36.2
2272 Male, age 74, both hemispheres 33.8
Pretectal area
nTPM: 31.8
2273 Male, age 74, both hemispheres 58.3
2407 Male, age 75, both hemispheres 38.7
2224 Female, age 72, unknown 34.1
2825 Male, age 18, unknown 32.0
2667 Female, age 75, unknown 31.6
2316 Male, age 76, right hemisphere 30.9
1817 Female, age 42, unknown 26.8
1815 Male, age 53, unknown 25.8
2007 Male, age 72, unknown 25.8
1944 Female, age 72, unknown 23.9
1816 Male, age 51, unknown 21.7
Red nucleus
nTPM: 38.3
2769 Male, age 72, unknown 42.1
1904 Male, age 53, unknown 41.8
1954 Female, age 42, unknown 41.8
2227 Male, age 72, unknown 41.4
1865 Male, age 51, unknown 41.2
1821 Female, age 72, unknown 39.4
2503 Female, age 72, unknown 37.8
2823 Male, age 76, right hemisphere 37.7
2725 Female, age 75, unknown 37.5
2785 Male, age 18, unknown 36.3
2584 Male, age 75, left hemisphere 31.7
2588 Male, age 74, left hemisphere 31.3
Substantia nigra
nTPM: 31.4
2699 Male, age 18, unknown 40.3
1851 Male, age 51, unknown 36.6
2241 Male, age 72, unknown 33.2
2409 Female, age 72, unknown 32.7
2583 Male, age 75, right hemisphere 32.6
2590 Female, age 75, unknown 31.3
2665 Male, age 74, both hemispheres 27.5
1916 Female, age 42, unknown 27.1
1889 Female, age 72, unknown 27.0
1941 Male, age 53, unknown 25.6
Superior colliculus
nTPM: 32.0
1995 Male, age 72, unknown 48.9
2664 Male, age 75, both hemispheres 38.9
1913 Female, age 42, unknown 37.5
2587 Male, age 74, left hemisphere 32.5
1839 Male, age 51, unknown 32.3
1895 Male, age 76, right hemisphere 27.8
1796 Male, age 53, unknown 26.8
2261 Male, age 18, unknown 26.1
2087 Female, age 72, unknown 25.0
2668 Female, age 75, unknown 24.4
Ventral tegmental area
nTPM: 31.4
2021 Male, age 53, unknown 35.3
1942 Male, age 51, unknown 33.7
2410 Female, age 72, unknown 32.4
1915 Female, age 42, unknown 30.2
2223 Female, age 72, unknown 29.7
2218 Male, age 76, both hemispheres 26.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 47.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 47.3
Samples: 139

Max nTPM: 137.7
Min nTPM: 16.0
Std nTPM: 19.5
Median nTPM: 43.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 137.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 108.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 96.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 90.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 86.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 82.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 77.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 76.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 75.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 72.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 72.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 71.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 71.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 71.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 71.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 71.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 70.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 68.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 67.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 67.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 66.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 66.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 65.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 65.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 63.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 62.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 62.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 61.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 61.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 61.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 58.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 58.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 58.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 58.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 58.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 57.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 57.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 57.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 57.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 57.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 57.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 56.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 56.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 56.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 55.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 54.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 54.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 52.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 52.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 51.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 50.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 49.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 48.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 48.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 48.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 48.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 47.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 47.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 47.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 47.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 46.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 46.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 45.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 45.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 43.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 43.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 42.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 42.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 41.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 40.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 40.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 40.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 40.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 40.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 39.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 39.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 39.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 39.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 38.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 38.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 38.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 38.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 37.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 37.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 37.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 37.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 37.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 36.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 36.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 36.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 35.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 35.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 34.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 34.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 33.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 32.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 32.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 32.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 32.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 32.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 31.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 31.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 30.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 30.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 30.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 30.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 29.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 29.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 27.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 27.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 27.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 27.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 27.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 27.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 27.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 27.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 27.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 26.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 26.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 26.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 24.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 24.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 24.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 23.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 21.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 20.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 19.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 17.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 16.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 16.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 139.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.2
FF:10158-103A5 76 years, female 139.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 32.2
Pig sample Sample description nTPM
Midbrain
nTPM: 31.9
Samples: 4

Max nTPM: 51.3
Min nTPM: 20.1
Sample A Female 51.3
Sample B Female 32.7
Sample C Male 20.1
Sample D Male 23.5
Periaqueductal gray
nTPM: 26.6
Samples: 3

Max nTPM: 28.4
Min nTPM: 24.4
Sample B Female 28.4
Sample C Male 24.4
Sample D Male 26.9
Substantia nigra
nTPM: 32.2
Samples: 4

Max nTPM: 50.4
Min nTPM: 23.4
Sample A Female 29.4
Sample B Female 23.4
Sample C Male 25.6
Sample D Male 50.4
Superior colliculi
nTPM: 28.3
Samples: 4

Max nTPM: 35.6
Min nTPM: 19.1
Sample A Female 35.6
Sample B Female 19.1
Sample C Male 27.4
Sample D Male 31.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 17.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 17.4
Samples: 4

Max nTPM: 18.3
Min nTPM: 15.8
Sample A Male 17.7
Sample B Male 18.3
Sample C Female 17.6
Sample D Female 15.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
71717592 Antisense, RP_050614_04_F12, Mouse strain C57BL/6J (56 days, male) 0.5
70473999 Antisense, RP_050614_04_F12, Mouse strain C57BL/6J (56 days, male) 0.2

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