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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:102.2 nTPM
HPA:102.2 nTPM
GTEx:59.4 nTPM
FANTOM5:170.3 Scaled Tags Per Million
Pig:13.5 nTPM
Mouse:7.3 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 102.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 84.9
2411 Female, age 72, unknown 101.2
1830 Male, age 51, unknown 98.8
2019 Male, age 18, unknown 94.3
1833 Male, age 53, unknown 92.3
2828 Female, age 72, unknown 85.4
1870 Female, age 42, unknown 84.1
2586 Male, age 75, left hemisphere 83.2
2219 Male, age 76, both hemispheres 73.8
1827 Male, age 72, unknown 70.1
2666 Male, age 74, left hemisphere 65.5
Dorsal raphe nucleus
nTPM: 68.6
2750 Male, age 76, both hemispheres 99.6
2016 Female, age 72, unknown 70.4
1828 Male, age 53, unknown 67.0
2047 Male, age 72, unknown 54.7
2298 Female, age 72, unknown 51.3
Inferior colliculus
nTPM: 63.3
2849 Male, age 72, unknown 68.1
1890 Male, age 53, unknown 65.5
1848 Female, age 42, unknown 64.3
2097 Female, age 72, unknown 55.3
Median raphe nucleus
nTPM: 57.3
2220 Male, age 76, midline 57.3
Pedunculopontine tegmental nucleus
nTPM: 78.8
2338 Male, age 61, both hemispheres 93.1
2334 Male, age 80, both hemispheres 72.1
1921 Female, age 85, both hemispheres 71.0
Periaquaductal grey, anterior
nTPM: 64.9
1947 Male, age 18, unknown 65.6
2502 Female, age 75, unknown 65.6
1795 Male, age 51, unknown 63.5
Periaquaductal grey, dorsal
nTPM: 60.6
2464 Female, age 72, unknown 80.4
1831 Male, age 72, unknown 62.9
2850 Male, age 76, both hemispheres 50.8
1840 Male, age 53, unknown 48.2
Periaquaductal grey, lateral
nTPM: 65.6
2272 Male, age 74, both hemispheres 75.2
2053 Male, age 18, unknown 68.7
2140 Male, age 76, both hemispheres 53.0
Pretectal area
nTPM: 71.3
2316 Male, age 76, right hemisphere 103.9
2667 Female, age 75, unknown 91.5
2407 Male, age 75, both hemispheres 83.8
1815 Male, age 53, unknown 78.3
2273 Male, age 74, both hemispheres 70.2
2825 Male, age 18, unknown 66.0
2007 Male, age 72, unknown 63.0
1817 Female, age 42, unknown 62.7
2224 Female, age 72, unknown 58.3
1944 Female, age 72, unknown 54.9
1816 Male, age 51, unknown 51.9
Red nucleus
nTPM: 102.2
2823 Male, age 76, right hemisphere 141.1
1865 Male, age 51, unknown 114.1
1904 Male, age 53, unknown 110.5
2227 Male, age 72, unknown 109.8
2769 Male, age 72, unknown 107.3
2503 Female, age 72, unknown 105.2
2785 Male, age 18, unknown 102.7
2588 Male, age 74, left hemisphere 99.2
2584 Male, age 75, left hemisphere 89.0
1821 Female, age 72, unknown 87.2
1954 Female, age 42, unknown 82.3
2725 Female, age 75, unknown 78.3
Substantia nigra
nTPM: 66.4
2583 Male, age 75, right hemisphere 81.2
2409 Female, age 72, unknown 78.9
1851 Male, age 51, unknown 76.5
2590 Female, age 75, unknown 72.2
2699 Male, age 18, unknown 71.8
1889 Female, age 72, unknown 62.7
1941 Male, age 53, unknown 60.0
2241 Male, age 72, unknown 57.3
2665 Male, age 74, both hemispheres 54.6
1916 Female, age 42, unknown 48.6
Superior colliculus
nTPM: 79.3
1913 Female, age 42, unknown 118.9
1995 Male, age 72, unknown 108.1
1895 Male, age 76, right hemisphere 95.9
1839 Male, age 51, unknown 73.9
2587 Male, age 74, left hemisphere 72.6
1796 Male, age 53, unknown 69.3
2664 Male, age 75, both hemispheres 66.8
2668 Female, age 75, unknown 65.3
2087 Female, age 72, unknown 62.3
2261 Male, age 18, unknown 59.4
Ventral tegmental area
nTPM: 73.8
2410 Female, age 72, unknown 91.9
2223 Female, age 72, unknown 82.1
2021 Male, age 53, unknown 77.1
1942 Male, age 51, unknown 68.7
2218 Male, age 76, both hemispheres 64.6
1915 Female, age 42, unknown 58.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 59.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 59.4
Samples: 139

Max nTPM: 221.1
Min nTPM: 14.4
Std nTPM: 33.5
Median nTPM: 52.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 221.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 168.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 156.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 152.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 149.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 138.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 132.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 129.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 114.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 112.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 110.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 107.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 104.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 100.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 91.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 89.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 88.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 87.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 85.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 84.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 83.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 82.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 81.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 79.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 76.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 75.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 74.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 73.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 73.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 71.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 70.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 68.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 68.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 67.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 65.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 65.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 64.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 64.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 64.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 64.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 63.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 62.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 61.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 61.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 59.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 59.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 59.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 58.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 58.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 57.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 57.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 55.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 54.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 53.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 53.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 53.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 52.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 52.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 52.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 51.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 49.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 49.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 49.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 48.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 47.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 47.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 47.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 46.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 46.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 45.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 45.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 44.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 44.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 44.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 43.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 41.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 41.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 41.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 40.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 40.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 40.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 40.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 40.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 39.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 39.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 39.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 38.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 37.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 37.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 37.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 36.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 35.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 35.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 35.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 32.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 32.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 32.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 31.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 31.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 30.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 29.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 29.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 28.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 28.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 27.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 27.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 27.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 26.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 24.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 24.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 24.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 24.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 23.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 23.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 23.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 22.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 20.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 17.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 16.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 15.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 14.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 170.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 170.3
FF:10158-103A5 76 years, female 170.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 13.5
Pig sample Sample description nTPM
Midbrain
nTPM: 11.6
Samples: 4

Max nTPM: 26.9
Min nTPM: 5.6
Sample A Female 26.9
Sample B Female 6.9
Sample C Male 5.6
Sample D Male 7.0
Periaqueductal gray
nTPM: 5.2
Samples: 3

Max nTPM: 5.5
Min nTPM: 4.7
Sample B Female 5.3
Sample C Male 4.7
Sample D Male 5.5
Substantia nigra
nTPM: 13.5
Samples: 4

Max nTPM: 21.0
Min nTPM: 9.8
Sample A Female 13.3
Sample B Female 9.8
Sample C Male 9.8
Sample D Male 21.0
Superior colliculi
nTPM: 7.8
Samples: 4

Max nTPM: 10.5
Min nTPM: 3.1
Sample A Female 10.5
Sample B Female 3.1
Sample C Male 7.3
Sample D Male 10.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 7.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 7.3
Samples: 4

Max nTPM: 7.6
Min nTPM: 6.8
Sample A Male 7.4
Sample B Male 7.2
Sample C Female 7.6
Sample D Female 6.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
1265 Antisense, RP_Baylor_103343, Mouse strain C57BL/6J (56 days, male) 0.4
71213755 Antisense, RP_050816_04_E10, Mouse strain C57BL/6J (56 days, male) 0.4
1266 Antisense, RP_Baylor_103343, Mouse strain C57BL/6J (56 days, male) 0.1

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