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MT-ATP6
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:80705.7 nTPM
HPA:80705.7 nTPM
GTEx:95253.6 nTPM
Pig:28507.8 nTPM
Mouse:23929.1 nTPM
Allen mouse:24.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 80705.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 74765.3
2586 Male, age 75, left hemisphere 88246.0
2219 Male, age 76, both hemispheres 86764.6
2666 Male, age 74, left hemisphere 79493.3
2828 Female, age 72, unknown 78408.4
1833 Male, age 53, unknown 73595.3
1830 Male, age 51, unknown 72040.3
1870 Female, age 42, unknown 71612.7
1827 Male, age 72, unknown 67637.0
2019 Male, age 18, unknown 66491.5
2411 Female, age 72, unknown 63363.7
Dorsal raphe nucleus
nTPM: 65304.0
1828 Male, age 53, unknown 72340.5
2047 Male, age 72, unknown 66838.9
2750 Male, age 76, both hemispheres 65291.4
2016 Female, age 72, unknown 63675.1
2298 Female, age 72, unknown 58373.9
Inferior colliculus
nTPM: 71113.3
2849 Male, age 72, unknown 85582.9
1890 Male, age 53, unknown 70196.0
1848 Female, age 42, unknown 68326.8
2097 Female, age 72, unknown 60347.3
Median raphe nucleus
nTPM: 80705.7
2220 Male, age 76, midline 80705.7
Pedunculopontine tegmental nucleus
nTPM: 72869.1
2334 Male, age 80, both hemispheres 78857.9
2338 Male, age 61, both hemispheres 75641.8
1921 Female, age 85, both hemispheres 64107.6
Periaquaductal grey, anterior
nTPM: 64900.5
2502 Female, age 75, unknown 67312.0
1795 Male, age 51, unknown 64056.6
1947 Male, age 18, unknown 63332.8
Periaquaductal grey, dorsal
nTPM: 70920.8
2850 Male, age 76, both hemispheres 83092.1
1831 Male, age 72, unknown 68657.6
2464 Female, age 72, unknown 67496.9
1840 Male, age 53, unknown 64436.6
Periaquaductal grey, lateral
nTPM: 63451.2
2140 Male, age 76, both hemispheres 66279.4
2053 Male, age 18, unknown 64217.9
2272 Male, age 74, both hemispheres 59856.3
Pretectal area
nTPM: 70283.2
1817 Female, age 42, unknown 77716.8
2667 Female, age 75, unknown 77276.8
1816 Male, age 51, unknown 76881.5
1944 Female, age 72, unknown 76830.8
1815 Male, age 53, unknown 74081.8
2007 Male, age 72, unknown 73255.4
2825 Male, age 18, unknown 70588.8
2407 Male, age 75, both hemispheres 65953.5
2224 Female, age 72, unknown 61600.2
2316 Male, age 76, right hemisphere 60028.8
2273 Male, age 74, both hemispheres 58900.9
Red nucleus
nTPM: 72500.6
2588 Male, age 74, left hemisphere 78655.2
2503 Female, age 72, unknown 77518.3
2584 Male, age 75, left hemisphere 76979.4
2823 Male, age 76, right hemisphere 75114.0
1954 Female, age 42, unknown 74037.3
1865 Male, age 51, unknown 72240.9
2785 Male, age 18, unknown 71247.2
2227 Male, age 72, unknown 70546.1
2769 Male, age 72, unknown 69938.8
1904 Male, age 53, unknown 68862.3
1821 Female, age 72, unknown 67716.2
2725 Female, age 75, unknown 67151.6
Substantia nigra
nTPM: 72694.8
2665 Male, age 74, both hemispheres 88798.3
2699 Male, age 18, unknown 87696.4
1916 Female, age 42, unknown 78101.7
1941 Male, age 53, unknown 72593.8
1889 Female, age 72, unknown 70310.9
2583 Male, age 75, right hemisphere 69959.3
1851 Male, age 51, unknown 66305.4
2590 Female, age 75, unknown 65568.1
2241 Male, age 72, unknown 64023.8
2409 Female, age 72, unknown 63590.8
Superior colliculus
nTPM: 69174.7
2664 Male, age 75, both hemispheres 81559.6
2587 Male, age 74, left hemisphere 71734.9
2087 Female, age 72, unknown 70104.5
2668 Female, age 75, unknown 68686.6
1913 Female, age 42, unknown 68398.4
1839 Male, age 51, unknown 68056.6
1895 Male, age 76, right hemisphere 67075.9
1995 Male, age 72, unknown 66902.8
1796 Male, age 53, unknown 64796.8
2261 Male, age 18, unknown 64431.3
Ventral tegmental area
nTPM: 70206.2
2218 Male, age 76, both hemispheres 79720.3
2223 Female, age 72, unknown 73006.1
1942 Male, age 51, unknown 69812.1
1915 Female, age 42, unknown 67069.7
2021 Male, age 53, unknown 66578.0
2410 Female, age 72, unknown 65050.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 95253.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 95253.6
Samples: 139

Max nTPM: 314273.7
Min nTPM: 16042.8
Std nTPM: 59814.6
Median nTPM: 74854.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 314273.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 295951.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 265334.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 251247.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 242994.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 222087.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 220914.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 215752.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 212399.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 204741.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 200584.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 197867.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 194254.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 192966.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 184332.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 183233.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 180441.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 176561.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 176334.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 173159.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 170911.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 170218.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 151990.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 151181.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 149589.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 147275.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 146096.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 139941.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 137336.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 132897.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128260.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 125846.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 124766.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 118129.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 116423.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 115086.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 113768.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112658.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106453.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 104827.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 104483.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103132.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102316.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 101538.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 100306.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 98704.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 97723.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 97606.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94075.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90602.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 89718.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 89637.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 89566.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 87793.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 87667.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 87096.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 86939.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 86664.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 85909.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 83254.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 80990.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 80245.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 79839.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 79755.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 79588.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 78122.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 75770.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 75578.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 75085.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 74854.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 73740.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 73491.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 73480.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 73332.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 71849.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 71502.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 71317.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 70549.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 70372.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69559.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 68889.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68042.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 67108.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 66699.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 66363.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 65792.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 65444.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 64196.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 62268.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60390.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 60111.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 59882.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 58730.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 57422.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 57357.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 56720.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 56078.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 55597.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55562.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 55524.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54858.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 54661.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 53813.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 53741.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 53706.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 53595.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 52186.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 51047.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50842.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50390.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 49859.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49528.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 49310.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49261.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 49161.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 47919.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 46537.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 46270.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 45693.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45150.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 44927.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 43435.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 43200.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 41690.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 40565.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 40155.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 40058.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 39662.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 38673.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 36310.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 35888.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 33630.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 33201.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 33029.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 31160.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 30772.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 27700.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 21570.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 16042.8
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 28507.8
Pig sample Sample description nTPM
Midbrain
nTPM: 28507.9
Samples: 4

Max nTPM: 38273.7
Min nTPM: 21534.5
Sample A Female 21534.5
Sample B Female 38273.7
Sample C Male 30966.8
Sample D Male 23256.5
Periaqueductal gray
nTPM: 21208.7
Samples: 3

Max nTPM: 23561.5
Min nTPM: 18229.2
Sample B Female 21835.3
Sample C Male 23561.5
Sample D Male 18229.2
Substantia nigra
nTPM: 24137.1
Samples: 4

Max nTPM: 32301.8
Min nTPM: 15254.7
Sample A Female 32301.8
Sample B Female 21282.1
Sample C Male 27709.9
Sample D Male 15254.7
Superior colliculi
nTPM: 23999.0
Samples: 4

Max nTPM: 30884.0
Min nTPM: 8565.1
Sample A Female 30155.8
Sample B Female 8565.1
Sample C Male 30884.0
Sample D Male 26391.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 23929.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 23929.1
Samples: 4

Max nTPM: 25055.6
Min nTPM: 23029.0
Sample A Male 25055.6
Sample B Male 23928.8
Sample C Female 23702.8
Sample D Female 23029.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 24.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.3
74357755 Antisense, RP_051219_04_A04, Mouse strain C57BL/6J (56 days, male) 24.3

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