Expression of HLA-C in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

HLA-C is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 380.85

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

455.9

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	1391.3
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	1093.1
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	1074.5
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	1071.2
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	902.1
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	891.2
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	877.3
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	862.4
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	855.9
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	843.5
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	799.4
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	791.6
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	783.1
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	775.1
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	759.4
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	755.9
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	718.6
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	713.5
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	709.4
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	701.8
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	667.6
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	660.2
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	648.3
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	639.6
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	629.0
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	629.0
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	628.8
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	623.1
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	620.2
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	606.8
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	604.5
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	602.1
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	596.3
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	591.2
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	587.7
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	586.8
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	586.2
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	585.7
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	585.5
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	582.7
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	581.8
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	571.8
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	571.2
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	569.2
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	553.9
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	551.5
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	551.1
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	547.5
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	544.1
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	543.2
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	543.1
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	541.7
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	541.2
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	536.7
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	529.8
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	527.0
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	523.9
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	521.7
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	516.2
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	507.3
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	507.2
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	506.4
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	504.5
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	497.5
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	486.2
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	479.7
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	473.8
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	472.5
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	468.1
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	467.0
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	466.6
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	464.0
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	461.5
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	460.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	458.0
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	454.1
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	448.4
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	446.3
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	446.0
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	445.2
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	445.2
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	443.0
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	441.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	436.9
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	436.2
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	434.8
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	430.3
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	419.2
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	418.8
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	417.7
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	417.3
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	416.6
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	410.6
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	410.2
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	408.7
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	403.5
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	403.3
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	403.0
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	401.4
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	400.9
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	398.2
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	392.2
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	389.6
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	386.9
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	385.0
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	384.7
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	383.6
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	383.4
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	378.3
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	371.8
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	368.8
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	368.5
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	368.5
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	366.8
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	362.6
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	361.8
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	360.6
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	360.1
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	357.7
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	346.6
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	342.7
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	337.7
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	332.8
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	330.2
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	328.8
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	327.3
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	326.6
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	320.5
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	318.3
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	313.7
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	312.7
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	310.4
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	303.7
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	300.7
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	293.2
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	290.6
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	290.2
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	289.6
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	289.6
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	286.6
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	285.0
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	284.9
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	284.3
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	282.4
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	281.8
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	280.5
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	272.8
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	272.7
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	263.5
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	260.2
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	254.3
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	253.2
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	251.2
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	248.8
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	247.6
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	247.0
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	246.6
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	246.3
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	246.0
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	242.3
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	242.0
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	236.6
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	227.8
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	224.6
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	218.3
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	207.6
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	197.7
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	194.4
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	181.2
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	175.4
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	167.8
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	162.1
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	150.2
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	138.9
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	135.8
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	95.0
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PANCREATIC CANCER - Protein expressionⁱ

Pending cancer tissue analysis