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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:485.3 nTPM
HPA:485.3 nTPM
GTEx:296.5 nTPM
FANTOM5:659.6 Scaled Tags Per Million
Pig:162.3 nTPM
Mouse:209.5 nTPM
Allen mouse:3.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 485.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 473.8
2666 Male, age 74, left hemisphere 491.8
2586 Male, age 75, left hemisphere 487.3
1870 Female, age 42, unknown 475.5
2828 Female, age 72, unknown 475.4
1833 Male, age 53, unknown 469.7
2411 Female, age 72, unknown 469.6
1830 Male, age 51, unknown 469.2
2219 Male, age 76, both hemispheres 468.2
1827 Male, age 72, unknown 465.8
2019 Male, age 18, unknown 465.4
Dorsal raphe nucleus
nTPM: 466.6
2750 Male, age 76, both hemispheres 470.9
2298 Female, age 72, unknown 467.2
2016 Female, age 72, unknown 466.9
2047 Male, age 72, unknown 464.3
1828 Male, age 53, unknown 463.5
Inferior colliculus
nTPM: 466.3
1890 Male, age 53, unknown 475.3
1848 Female, age 42, unknown 469.3
2097 Female, age 72, unknown 460.5
2849 Male, age 72, unknown 460.0
Median raphe nucleus
nTPM: 475.4
2220 Male, age 76, midline 475.4
Pedunculopontine tegmental nucleus
nTPM: 481.8
2338 Male, age 61, both hemispheres 506.6
2334 Male, age 80, both hemispheres 486.4
1921 Female, age 85, both hemispheres 452.3
Periaquaductal grey, anterior
nTPM: 473.5
2502 Female, age 75, unknown 483.5
1947 Male, age 18, unknown 471.4
1795 Male, age 51, unknown 465.7
Periaquaductal grey, dorsal
nTPM: 456.8
1831 Male, age 72, unknown 465.0
1840 Male, age 53, unknown 461.0
2464 Female, age 72, unknown 455.9
2850 Male, age 76, both hemispheres 445.4
Periaquaductal grey, lateral
nTPM: 468.0
2272 Male, age 74, both hemispheres 484.8
2053 Male, age 18, unknown 471.7
2140 Male, age 76, both hemispheres 447.6
Pretectal area
nTPM: 462.6
2273 Male, age 74, both hemispheres 469.0
2407 Male, age 75, both hemispheres 465.8
1815 Male, age 53, unknown 465.7
2224 Female, age 72, unknown 465.6
1944 Female, age 72, unknown 463.8
1817 Female, age 42, unknown 463.1
2316 Male, age 76, right hemisphere 462.6
2825 Male, age 18, unknown 462.6
2007 Male, age 72, unknown 460.3
1816 Male, age 51, unknown 459.0
2667 Female, age 75, unknown 450.6
Red nucleus
nTPM: 474.7
2503 Female, age 72, unknown 501.2
1865 Male, age 51, unknown 487.3
1904 Male, age 53, unknown 483.8
2584 Male, age 75, left hemisphere 477.9
2769 Male, age 72, unknown 477.1
2785 Male, age 18, unknown 475.2
1821 Female, age 72, unknown 474.7
2227 Male, age 72, unknown 472.2
1954 Female, age 42, unknown 468.5
2823 Male, age 76, right hemisphere 462.3
2725 Female, age 75, unknown 459.7
2588 Male, age 74, left hemisphere 456.3
Substantia nigra
nTPM: 485.3
2699 Male, age 18, unknown 501.2
2665 Male, age 74, both hemispheres 500.1
1851 Male, age 51, unknown 498.0
1916 Female, age 42, unknown 490.7
2590 Female, age 75, unknown 488.1
2409 Female, age 72, unknown 486.7
2241 Male, age 72, unknown 476.7
1889 Female, age 72, unknown 475.6
2583 Male, age 75, right hemisphere 471.3
1941 Male, age 53, unknown 465.1
Superior colliculus
nTPM: 473.9
1995 Male, age 72, unknown 490.7
2668 Female, age 75, unknown 490.5
2587 Male, age 74, left hemisphere 485.5
1913 Female, age 42, unknown 485.1
2664 Male, age 75, both hemispheres 475.6
1796 Male, age 53, unknown 471.5
1839 Male, age 51, unknown 469.5
2261 Male, age 18, unknown 463.5
2087 Female, age 72, unknown 458.4
1895 Male, age 76, right hemisphere 448.4
Ventral tegmental area
nTPM: 481.0
1915 Female, age 42, unknown 486.2
2410 Female, age 72, unknown 485.1
2021 Male, age 53, unknown 482.0
2223 Female, age 72, unknown 479.6
2218 Male, age 76, both hemispheres 476.7
1942 Male, age 51, unknown 476.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 296.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 296.5
Samples: 139

Max nTPM: 664.5
Min nTPM: 145.2
Std nTPM: 82.2
Median nTPM: 278.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 664.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 567.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 522.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 505.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 501.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 473.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 463.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 447.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 442.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 434.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 418.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 410.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 408.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 395.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 391.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 384.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 383.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 382.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 377.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 374.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 374.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 371.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 371.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 369.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 369.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 366.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 364.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 355.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 352.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 352.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 352.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 348.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 348.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 347.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 345.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 337.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 336.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 333.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 333.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 331.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 325.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 324.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 318.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 318.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 315.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 315.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 313.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 312.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 308.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 302.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 300.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 298.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 298.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 298.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 297.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 295.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 290.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 287.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 286.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 286.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 284.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 284.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 283.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 283.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 283.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 280.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 280.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 279.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 279.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 278.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 278.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 275.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 274.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 274.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 274.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 273.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 269.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 268.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 268.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 265.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 264.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 263.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 262.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 261.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 261.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 261.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 260.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 260.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 259.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 259.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 255.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 254.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 251.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 251.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 250.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 250.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 250.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 250.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 249.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 247.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 244.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 240.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 239.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 238.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 237.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 237.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 236.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 234.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 232.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 231.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 229.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 228.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 227.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 226.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 225.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 225.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 223.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 222.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 221.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 216.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 216.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 216.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 215.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 215.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 213.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 212.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 211.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 209.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 209.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 204.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 201.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 199.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 198.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 194.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 194.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 190.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 189.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 184.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 145.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 659.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 659.6
FF:10158-103A5 76 years, female 659.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 162.3
Pig sample Sample description nTPM
Midbrain
nTPM: 144.8
Samples: 4

Max nTPM: 200.3
Min nTPM: 111.3
Sample A Female 200.3
Sample B Female 142.4
Sample C Male 125.2
Sample D Male 111.3
Periaqueductal gray
nTPM: 124.3
Samples: 3

Max nTPM: 137.2
Min nTPM: 110.5
Sample B Female 125.3
Sample C Male 137.2
Sample D Male 110.5
Substantia nigra
nTPM: 151.4
Samples: 4

Max nTPM: 188.2
Min nTPM: 121.3
Sample A Female 188.2
Sample B Female 160.5
Sample C Male 135.4
Sample D Male 121.3
Superior colliculi
nTPM: 162.3
Samples: 4

Max nTPM: 199.8
Min nTPM: 132.3
Sample A Female 180.7
Sample B Female 199.8
Sample C Male 132.3
Sample D Male 136.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 209.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 209.5
Samples: 4

Max nTPM: 234.3
Min nTPM: 186.0
Sample A Male 234.3
Sample B Male 197.4
Sample C Female 186.0
Sample D Female 220.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.6
71021172 Antisense, RP_050531_01_G07, Mouse strain C57BL/6J (56 days, male) 3.6

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