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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:64.2 nTPM
HPA:64.2 nTPM
GTEx:102.2 nTPM
FANTOM5:92.2 Scaled Tags Per Million
Pig:23.2 nTPM
Mouse:153.1 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 64.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.5
2019 Male, age 18, unknown 65.2
2411 Female, age 72, unknown 64.2
1870 Female, age 42, unknown 63.8
2828 Female, age 72, unknown 63.2
1833 Male, age 53, unknown 63.1
1827 Male, age 72, unknown 62.0
2666 Male, age 74, left hemisphere 61.9
1830 Male, age 51, unknown 61.7
2586 Male, age 75, left hemisphere 61.4
2219 Male, age 76, both hemispheres 59.1
Dorsal raphe nucleus
nTPM: 63.2
2298 Female, age 72, unknown 65.1
2750 Male, age 76, both hemispheres 64.2
2016 Female, age 72, unknown 62.7
1828 Male, age 53, unknown 62.3
2047 Male, age 72, unknown 61.8
Inferior colliculus
nTPM: 61.1
2097 Female, age 72, unknown 62.1
1890 Male, age 53, unknown 62.0
1848 Female, age 42, unknown 61.2
2849 Male, age 72, unknown 59.3
Median raphe nucleus
nTPM: 61.9
2220 Male, age 76, midline 61.9
Pedunculopontine tegmental nucleus
nTPM: 62.9
2338 Male, age 61, both hemispheres 63.8
2334 Male, age 80, both hemispheres 63.2
1921 Female, age 85, both hemispheres 61.8
Periaquaductal grey, anterior
nTPM: 62.1
2502 Female, age 75, unknown 63.1
1795 Male, age 51, unknown 62.3
1947 Male, age 18, unknown 61.1
Periaquaductal grey, dorsal
nTPM: 61.0
1831 Male, age 72, unknown 62.0
2464 Female, age 72, unknown 61.4
2850 Male, age 76, both hemispheres 60.8
1840 Male, age 53, unknown 60.0
Periaquaductal grey, lateral
nTPM: 62.4
2053 Male, age 18, unknown 63.2
2272 Male, age 74, both hemispheres 62.5
2140 Male, age 76, both hemispheres 61.4
Pretectal area
nTPM: 63.3
2007 Male, age 72, unknown 64.8
1816 Male, age 51, unknown 64.4
2667 Female, age 75, unknown 64.1
2273 Male, age 74, both hemispheres 63.9
1815 Male, age 53, unknown 63.8
1817 Female, age 42, unknown 63.5
2316 Male, age 76, right hemisphere 63.5
2224 Female, age 72, unknown 62.5
1944 Female, age 72, unknown 62.2
2825 Male, age 18, unknown 61.9
2407 Male, age 75, both hemispheres 61.6
Red nucleus
nTPM: 64.2
1821 Female, age 72, unknown 67.3
1904 Male, age 53, unknown 65.9
1865 Male, age 51, unknown 65.4
2503 Female, age 72, unknown 65.3
2227 Male, age 72, unknown 65.0
2588 Male, age 74, left hemisphere 64.3
2823 Male, age 76, right hemisphere 64.2
2769 Male, age 72, unknown 63.7
2785 Male, age 18, unknown 63.2
1954 Female, age 42, unknown 62.8
2725 Female, age 75, unknown 61.9
2584 Male, age 75, left hemisphere 61.5
Substantia nigra
nTPM: 62.9
1851 Male, age 51, unknown 66.5
1916 Female, age 42, unknown 65.2
2699 Male, age 18, unknown 63.4
2590 Female, age 75, unknown 63.0
1889 Female, age 72, unknown 62.9
1941 Male, age 53, unknown 62.2
2241 Male, age 72, unknown 62.1
2409 Female, age 72, unknown 61.7
2665 Male, age 74, both hemispheres 61.5
2583 Male, age 75, right hemisphere 60.6
Superior colliculus
nTPM: 63.1
2587 Male, age 74, left hemisphere 65.2
1995 Male, age 72, unknown 65.1
1913 Female, age 42, unknown 64.6
2668 Female, age 75, unknown 63.3
2664 Male, age 75, both hemispheres 62.8
2261 Male, age 18, unknown 62.4
1796 Male, age 53, unknown 62.3
1895 Male, age 76, right hemisphere 62.1
2087 Female, age 72, unknown 61.9
1839 Male, age 51, unknown 61.3
Ventral tegmental area
nTPM: 63.7
2410 Female, age 72, unknown 66.0
2223 Female, age 72, unknown 65.1
1915 Female, age 42, unknown 63.9
2021 Male, age 53, unknown 63.3
2218 Male, age 76, both hemispheres 62.9
1942 Male, age 51, unknown 60.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 102.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 102.2
Samples: 139

Max nTPM: 304.4
Min nTPM: 36.5
Std nTPM: 37.0
Median nTPM: 94.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 304.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 248.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 204.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 194.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 193.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 180.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 174.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 169.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 159.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 158.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 158.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 155.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 153.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 151.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 144.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 144.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 140.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 137.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 132.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 128.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 128.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 128.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 123.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 122.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 122.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 122.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 121.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 121.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 120.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 119.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 118.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 117.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 117.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 116.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 114.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 114.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 113.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 113.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 111.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 110.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 110.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 109.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 108.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 108.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 108.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 106.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 104.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 103.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 103.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 102.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 101.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 100.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 100.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 100.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 99.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 99.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 99.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 98.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 98.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 97.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 97.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 96.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 96.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 95.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 95.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 95.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 94.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 94.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 94.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 93.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 92.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 92.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 92.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 91.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 91.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 90.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 90.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 89.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 89.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 89.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 87.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 87.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 87.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 86.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 86.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 85.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 85.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 84.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 84.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 84.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 82.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 81.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 81.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 81.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 81.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 80.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 80.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 79.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 79.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 78.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 77.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 77.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 77.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 76.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 76.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 75.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 75.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 75.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 75.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 72.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 71.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 71.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 70.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 70.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 70.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 69.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 67.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 67.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 66.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 65.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 63.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 63.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 60.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 59.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 59.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 57.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 56.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 53.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 51.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 36.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 92.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 92.2
FF:10158-103A5 76 years, female 92.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 23.2
Pig sample Sample description nTPM
Midbrain
nTPM: 21.6
Samples: 4

Max nTPM: 26.9
Min nTPM: 14.9
Sample A Female 26.9
Sample B Female 24.6
Sample C Male 20.1
Sample D Male 14.9
Periaqueductal gray
nTPM: 18.0
Samples: 3

Max nTPM: 19.3
Min nTPM: 16.8
Sample B Female 17.8
Sample C Male 16.8
Sample D Male 19.3
Substantia nigra
nTPM: 23.2
Samples: 4

Max nTPM: 24.7
Min nTPM: 20.3
Sample A Female 24.5
Sample B Female 24.7
Sample C Male 23.4
Sample D Male 20.3
Superior colliculi
nTPM: 23.1
Samples: 4

Max nTPM: 27.2
Min nTPM: 20.9
Sample A Female 27.2
Sample B Female 21.6
Sample C Male 22.6
Sample D Male 20.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 153.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 153.1
Samples: 4

Max nTPM: 170.4
Min nTPM: 132.9
Sample A Male 168.0
Sample B Male 141.0
Sample C Female 132.9
Sample D Female 170.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
69407110 Antisense, RP_050412_02_H08, Mouse strain C57BL/6J (56 days, male) 0.0

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