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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA001217
In normal tissue there was a strong cytoplasmic staining in plasma cells. Also rare bone marrow poetic cells were stained as well as a few cells in spleen and in lymphatic cortex. There was sometimes a positivity in glandular epithelium, for example in rectum. Prostate showed strong staining.
Cancers mostly negative.
HPA006013
This antibody showed a strong cytoplasmic staining in plasma cells. There was secreted positivity in mucosal surfaces and in some gland lumina. Some lymphatic cells were weakly positive. In other tissues there was a rather weak, probably unspecific background staining. There was also positivity in stroma.
Only rare tumors were positive but there was often some background staining in some cells.
The Human Protein Atlas project is funded
