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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:213.0 nTPM
HPA:213.0 nTPM
GTEx:101.9 nTPM
FANTOM5:12.6 Scaled Tags Per Million
Pig:87.8 nTPM
Mouse:167.5 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 213.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 175.3
2666 Male, age 74, left hemisphere 191.8
2411 Female, age 72, unknown 185.3
2828 Female, age 72, unknown 184.9
2586 Male, age 75, left hemisphere 181.2
1833 Male, age 53, unknown 178.6
1830 Male, age 51, unknown 174.6
1870 Female, age 42, unknown 174.3
1827 Male, age 72, unknown 170.2
2219 Male, age 76, both hemispheres 166.6
2019 Male, age 18, unknown 145.1
Dorsal raphe nucleus
nTPM: 200.5
2298 Female, age 72, unknown 214.5
2047 Male, age 72, unknown 209.1
1828 Male, age 53, unknown 200.6
2750 Male, age 76, both hemispheres 192.1
2016 Female, age 72, unknown 186.1
Inferior colliculus
nTPM: 168.2
2097 Female, age 72, unknown 177.0
1890 Male, age 53, unknown 171.4
1848 Female, age 42, unknown 163.6
2849 Male, age 72, unknown 160.9
Median raphe nucleus
nTPM: 198.3
2220 Male, age 76, midline 198.3
Pedunculopontine tegmental nucleus
nTPM: 193.4
2338 Male, age 61, both hemispheres 230.8
2334 Male, age 80, both hemispheres 185.8
1921 Female, age 85, both hemispheres 163.5
Periaquaductal grey, anterior
nTPM: 213.0
1947 Male, age 18, unknown 242.2
1795 Male, age 51, unknown 211.7
2502 Female, age 75, unknown 185.1
Periaquaductal grey, dorsal
nTPM: 179.6
1831 Male, age 72, unknown 187.4
2850 Male, age 76, both hemispheres 182.6
1840 Male, age 53, unknown 178.6
2464 Female, age 72, unknown 169.9
Periaquaductal grey, lateral
nTPM: 189.4
2272 Male, age 74, both hemispheres 195.9
2053 Male, age 18, unknown 193.0
2140 Male, age 76, both hemispheres 179.2
Pretectal area
nTPM: 170.8
2825 Male, age 18, unknown 201.7
2224 Female, age 72, unknown 186.6
2273 Male, age 74, both hemispheres 185.6
2316 Male, age 76, right hemisphere 172.9
2667 Female, age 75, unknown 167.8
1817 Female, age 42, unknown 166.3
1944 Female, age 72, unknown 163.9
2407 Male, age 75, both hemispheres 163.4
1815 Male, age 53, unknown 160.7
2007 Male, age 72, unknown 155.5
1816 Male, age 51, unknown 154.5
Red nucleus
nTPM: 182.6
2725 Female, age 75, unknown 205.2
2503 Female, age 72, unknown 203.5
2227 Male, age 72, unknown 193.5
2769 Male, age 72, unknown 192.7
1865 Male, age 51, unknown 187.3
1904 Male, age 53, unknown 185.2
1954 Female, age 42, unknown 184.2
1821 Female, age 72, unknown 180.4
2584 Male, age 75, left hemisphere 175.7
2823 Male, age 76, right hemisphere 175.1
2588 Male, age 74, left hemisphere 159.5
2785 Male, age 18, unknown 148.3
Substantia nigra
nTPM: 209.7
2699 Male, age 18, unknown 234.3
1916 Female, age 42, unknown 230.1
1851 Male, age 51, unknown 227.6
2665 Male, age 74, both hemispheres 224.2
2590 Female, age 75, unknown 213.6
2583 Male, age 75, right hemisphere 199.8
2241 Male, age 72, unknown 198.8
2409 Female, age 72, unknown 197.4
1941 Male, age 53, unknown 193.5
1889 Female, age 72, unknown 177.1
Superior colliculus
nTPM: 174.0
2261 Male, age 18, unknown 189.2
2587 Male, age 74, left hemisphere 185.0
1796 Male, age 53, unknown 181.5
1995 Male, age 72, unknown 174.2
1839 Male, age 51, unknown 172.6
2087 Female, age 72, unknown 172.5
2668 Female, age 75, unknown 170.8
1913 Female, age 42, unknown 169.6
2664 Male, age 75, both hemispheres 168.6
1895 Male, age 76, right hemisphere 155.9
Ventral tegmental area
nTPM: 207.8
1915 Female, age 42, unknown 227.4
2410 Female, age 72, unknown 210.6
1942 Male, age 51, unknown 207.2
2021 Male, age 53, unknown 207.0
2218 Male, age 76, both hemispheres 197.3
2223 Female, age 72, unknown 197.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 101.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 101.9
Samples: 139

Max nTPM: 253.3
Min nTPM: 39.4
Std nTPM: 35.5
Median nTPM: 94.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 253.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 202.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 195.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 183.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 179.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 170.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 169.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 162.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 160.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 156.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 154.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 153.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 152.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 147.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 147.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 145.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 145.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 144.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 140.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 140.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 138.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 137.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 133.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 131.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 129.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 128.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 127.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 127.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 125.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 124.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 124.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 124.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 123.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 122.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 121.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 120.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 120.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 119.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 118.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 118.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 117.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 117.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 115.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 115.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 115.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 115.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 114.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 114.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 113.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 113.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 111.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 110.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 108.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 106.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 104.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 104.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 102.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 102.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 101.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 100.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 99.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 98.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 97.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 96.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 95.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 95.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 94.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 94.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 94.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 93.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 93.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 92.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 92.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 92.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 91.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 91.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 89.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 89.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 89.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 89.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 88.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 88.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 86.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 86.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 86.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 86.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 85.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 84.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 84.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 84.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 83.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 83.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 83.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 82.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 81.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 80.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 80.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 79.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 77.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 77.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 77.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 76.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 76.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 76.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 75.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 75.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 74.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 73.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 73.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 72.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 72.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 71.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 70.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 67.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 66.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 66.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 65.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 63.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 63.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 62.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 60.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 55.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 54.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 51.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 47.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 47.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 44.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 44.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 43.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 39.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 12.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 12.6
FF:10158-103A5 76 years, female 12.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 87.8
Pig sample Sample description nTPM
Midbrain
nTPM: 70.1
Samples: 4

Max nTPM: 102.5
Min nTPM: 48.1
Sample A Female 102.5
Sample B Female 79.3
Sample C Male 48.1
Sample D Male 50.3
Periaqueductal gray
nTPM: 77.2
Samples: 3

Max nTPM: 102.9
Min nTPM: 61.4
Sample B Female 61.4
Sample C Male 102.9
Sample D Male 67.2
Substantia nigra
nTPM: 87.8
Samples: 4

Max nTPM: 117.9
Min nTPM: 53.5
Sample A Female 117.9
Sample B Female 78.4
Sample C Male 101.4
Sample D Male 53.5
Superior colliculi
nTPM: 61.5
Samples: 4

Max nTPM: 74.6
Min nTPM: 46.1
Sample A Female 74.6
Sample B Female 66.3
Sample C Male 46.1
Sample D Male 59.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 167.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 167.5
Samples: 4

Max nTPM: 188.4
Min nTPM: 154.6
Sample A Male 188.4
Sample B Male 157.9
Sample C Female 154.6
Sample D Female 168.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
74003380 Antisense, RP_051130_01_E06, Mouse strain C57BL/6J (56 days, male) 0.2

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