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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:33.4 nTPM
HPA:33.4 nTPM
GTEx:31.9 nTPM
FANTOM5:67.3 Scaled Tags Per Million
Pig:14.2 nTPM
Mouse:48.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 33.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 30.5
2586 Male, age 75, left hemisphere 35.3
2411 Female, age 72, unknown 33.0
1830 Male, age 51, unknown 31.5
2019 Male, age 18, unknown 30.9
1870 Female, age 42, unknown 29.8
2828 Female, age 72, unknown 29.5
1833 Male, age 53, unknown 29.4
2666 Male, age 74, left hemisphere 29.0
2219 Male, age 76, both hemispheres 28.8
1827 Male, age 72, unknown 28.1
Dorsal raphe nucleus
nTPM: 26.8
2750 Male, age 76, both hemispheres 31.7
2047 Male, age 72, unknown 27.8
1828 Male, age 53, unknown 25.9
2298 Female, age 72, unknown 24.5
2016 Female, age 72, unknown 24.0
Inferior colliculus
nTPM: 25.4
1890 Male, age 53, unknown 26.7
2849 Male, age 72, unknown 25.5
1848 Female, age 42, unknown 25.2
2097 Female, age 72, unknown 24.2
Median raphe nucleus
nTPM: 26.5
2220 Male, age 76, midline 26.5
Pedunculopontine tegmental nucleus
nTPM: 28.0
1921 Female, age 85, both hemispheres 29.5
2334 Male, age 80, both hemispheres 28.4
2338 Male, age 61, both hemispheres 26.1
Periaquaductal grey, anterior
nTPM: 28.0
2502 Female, age 75, unknown 29.7
1795 Male, age 51, unknown 27.3
1947 Male, age 18, unknown 27.0
Periaquaductal grey, dorsal
nTPM: 24.2
2464 Female, age 72, unknown 27.6
1831 Male, age 72, unknown 24.7
1840 Male, age 53, unknown 22.9
2850 Male, age 76, both hemispheres 21.6
Periaquaductal grey, lateral
nTPM: 25.5
2053 Male, age 18, unknown 27.6
2272 Male, age 74, both hemispheres 26.1
2140 Male, age 76, both hemispheres 22.9
Pretectal area
nTPM: 27.6
2407 Male, age 75, both hemispheres 32.7
2316 Male, age 76, right hemisphere 29.9
2667 Female, age 75, unknown 28.9
2007 Male, age 72, unknown 28.4
1815 Male, age 53, unknown 28.2
2825 Male, age 18, unknown 28.2
1817 Female, age 42, unknown 27.0
1816 Male, age 51, unknown 26.2
2273 Male, age 74, both hemispheres 24.9
2224 Female, age 72, unknown 24.7
1944 Female, age 72, unknown 24.3
Red nucleus
nTPM: 33.4
2588 Male, age 74, left hemisphere 37.7
1904 Male, age 53, unknown 35.4
2584 Male, age 75, left hemisphere 35.4
2769 Male, age 72, unknown 35.2
1865 Male, age 51, unknown 34.2
2227 Male, age 72, unknown 34.0
2823 Male, age 76, right hemisphere 33.2
2503 Female, age 72, unknown 32.8
2785 Male, age 18, unknown 32.0
1954 Female, age 42, unknown 31.0
1821 Female, age 72, unknown 30.5
2725 Female, age 75, unknown 29.1
Substantia nigra
nTPM: 29.2
2583 Male, age 75, right hemisphere 33.0
2409 Female, age 72, unknown 31.7
1851 Male, age 51, unknown 30.1
1941 Male, age 53, unknown 30.0
1916 Female, age 42, unknown 29.6
2699 Male, age 18, unknown 29.0
2590 Female, age 75, unknown 27.8
2665 Male, age 74, both hemispheres 27.8
1889 Female, age 72, unknown 26.8
2241 Male, age 72, unknown 25.9
Superior colliculus
nTPM: 28.6
2664 Male, age 75, both hemispheres 31.3
2668 Female, age 75, unknown 30.5
1913 Female, age 42, unknown 29.9
1995 Male, age 72, unknown 28.8
1839 Male, age 51, unknown 28.7
2587 Male, age 74, left hemisphere 27.8
1796 Male, age 53, unknown 27.6
2087 Female, age 72, unknown 27.3
2261 Male, age 18, unknown 27.2
1895 Male, age 76, right hemisphere 26.6
Ventral tegmental area
nTPM: 29.5
2223 Female, age 72, unknown 33.3
2410 Female, age 72, unknown 31.5
2021 Male, age 53, unknown 28.8
1942 Male, age 51, unknown 28.7
2218 Male, age 76, both hemispheres 27.8
1915 Female, age 42, unknown 27.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 31.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 31.9
Samples: 139

Max nTPM: 53.1
Min nTPM: 18.7
Std nTPM: 6.0
Median nTPM: 32.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 53.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 50.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 45.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 43.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 43.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 42.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 42.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 41.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 40.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 38.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 38.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 38.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 37.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 37.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 37.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 37.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 37.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 36.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 36.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 36.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 36.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 36.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 35.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 35.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 35.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 35.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 35.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 35.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 35.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 35.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 35.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 35.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 35.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 35.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 34.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 34.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 34.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 34.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 34.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 34.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 34.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 33.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 33.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 33.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 33.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 33.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 33.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 33.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 33.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 33.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 32.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 32.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 32.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 32.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 32.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 32.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 32.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 32.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 32.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 32.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 31.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 31.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 31.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 31.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 31.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 31.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 31.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 30.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 30.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 30.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 30.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 30.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 30.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 30.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 30.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 29.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 29.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 29.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 29.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 28.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 28.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 28.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 28.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 28.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 28.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 28.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 28.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 28.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 28.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 28.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 28.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 28.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 28.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 28.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 27.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 27.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 27.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 27.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 27.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 27.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 27.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 26.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 25.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 25.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 25.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 25.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 25.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 25.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 25.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 25.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 24.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 24.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 23.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 23.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 23.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 22.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 22.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 22.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 22.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 21.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 21.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 21.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 20.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 20.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 18.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 67.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 67.3
FF:10158-103A5 76 years, female 67.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 14.2
Pig sample Sample description nTPM
Midbrain
nTPM: 13.4
Samples: 4

Max nTPM: 15.8
Min nTPM: 10.7
Sample A Female 13.8
Sample B Female 10.7
Sample C Male 15.8
Sample D Male 13.3
Periaqueductal gray
nTPM: 10.5
Samples: 3

Max nTPM: 11.8
Min nTPM: 9.1
Sample B Female 10.5
Sample C Male 11.8
Sample D Male 9.1
Substantia nigra
nTPM: 12.4
Samples: 4

Max nTPM: 15.5
Min nTPM: 10.9
Sample A Female 15.5
Sample B Female 10.9
Sample C Male 12.1
Sample D Male 11.0
Superior colliculi
nTPM: 14.2
Samples: 4

Max nTPM: 15.6
Min nTPM: 12.6
Sample A Female 15.6
Sample B Female 12.6
Sample C Male 15.0
Sample D Male 13.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 48.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 48.0
Samples: 4

Max nTPM: 52.9
Min nTPM: 43.1
Sample A Male 52.9
Sample B Male 49.4
Sample C Female 43.1
Sample D Female 46.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
601190 Antisense, RP_040831_01_H09, Mouse strain C57BL/6J (56 days, male) 0.1

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