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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:648.0 nTPM
HPA:648.0 nTPM
GTEx:540.4 nTPM
FANTOM5:86.8 Scaled Tags Per Million
Pig:66.6 nTPM
Mouse:266.0 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 648.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 618.4
2019 Male, age 18, unknown 630.5
1827 Male, age 72, unknown 629.1
2219 Male, age 76, both hemispheres 621.6
1870 Female, age 42, unknown 620.3
2828 Female, age 72, unknown 620.0
2586 Male, age 75, left hemisphere 616.5
1833 Male, age 53, unknown 613.1
2666 Male, age 74, left hemisphere 611.5
1830 Male, age 51, unknown 611.0
2411 Female, age 72, unknown 610.3
Dorsal raphe nucleus
nTPM: 623.4
1828 Male, age 53, unknown 635.4
2298 Female, age 72, unknown 633.3
2047 Male, age 72, unknown 627.1
2750 Male, age 76, both hemispheres 617.3
2016 Female, age 72, unknown 603.9
Inferior colliculus
nTPM: 628.0
2097 Female, age 72, unknown 631.7
1890 Male, age 53, unknown 630.5
1848 Female, age 42, unknown 628.4
2849 Male, age 72, unknown 621.3
Median raphe nucleus
nTPM: 629.3
2220 Male, age 76, midline 629.3
Pedunculopontine tegmental nucleus
nTPM: 648.0
2338 Male, age 61, both hemispheres 663.3
1921 Female, age 85, both hemispheres 645.2
2334 Male, age 80, both hemispheres 635.5
Periaquaductal grey, anterior
nTPM: 622.8
1947 Male, age 18, unknown 629.2
1795 Male, age 51, unknown 628.6
2502 Female, age 75, unknown 610.7
Periaquaductal grey, dorsal
nTPM: 617.5
2850 Male, age 76, both hemispheres 635.7
1840 Male, age 53, unknown 614.7
1831 Male, age 72, unknown 610.5
2464 Female, age 72, unknown 609.0
Periaquaductal grey, lateral
nTPM: 618.7
2272 Male, age 74, both hemispheres 624.9
2053 Male, age 18, unknown 621.8
2140 Male, age 76, both hemispheres 609.5
Pretectal area
nTPM: 642.6
1817 Female, age 42, unknown 671.6
1816 Male, age 51, unknown 665.8
2007 Male, age 72, unknown 663.8
2667 Female, age 75, unknown 659.5
1944 Female, age 72, unknown 657.7
1815 Male, age 53, unknown 645.6
2224 Female, age 72, unknown 631.9
2273 Male, age 74, both hemispheres 624.9
2407 Male, age 75, both hemispheres 621.1
2825 Male, age 18, unknown 618.9
2316 Male, age 76, right hemisphere 608.2
Red nucleus
nTPM: 623.7
1821 Female, age 72, unknown 658.6
2725 Female, age 75, unknown 638.2
2823 Male, age 76, right hemisphere 634.8
2503 Female, age 72, unknown 627.1
2785 Male, age 18, unknown 624.6
1865 Male, age 51, unknown 619.7
2227 Male, age 72, unknown 619.0
1954 Female, age 42, unknown 618.0
2769 Male, age 72, unknown 617.2
1904 Male, age 53, unknown 611.9
2584 Male, age 75, left hemisphere 607.7
2588 Male, age 74, left hemisphere 607.3
Substantia nigra
nTPM: 635.4
1916 Female, age 42, unknown 660.5
1889 Female, age 72, unknown 652.4
1851 Male, age 51, unknown 642.7
1941 Male, age 53, unknown 638.2
2409 Female, age 72, unknown 635.9
2665 Male, age 74, both hemispheres 634.4
2241 Male, age 72, unknown 634.0
2699 Male, age 18, unknown 631.2
2590 Female, age 75, unknown 615.1
2583 Male, age 75, right hemisphere 609.8
Superior colliculus
nTPM: 624.0
2587 Male, age 74, left hemisphere 639.3
2087 Female, age 72, unknown 635.5
1796 Male, age 53, unknown 631.6
1895 Male, age 76, right hemisphere 630.2
2668 Female, age 75, unknown 626.2
2261 Male, age 18, unknown 622.2
1839 Male, age 51, unknown 619.0
1913 Female, age 42, unknown 614.8
1995 Male, age 72, unknown 614.5
2664 Male, age 75, both hemispheres 607.2
Ventral tegmental area
nTPM: 627.4
2218 Male, age 76, both hemispheres 643.1
1915 Female, age 42, unknown 637.9
2410 Female, age 72, unknown 632.6
2223 Female, age 72, unknown 623.5
2021 Male, age 53, unknown 616.4
1942 Male, age 51, unknown 611.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 540.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 540.4
Samples: 139

Max nTPM: 958.5
Min nTPM: 233.9
Std nTPM: 139.0
Median nTPM: 522.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 958.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 950.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 903.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 880.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 848.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 832.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 818.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 814.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 800.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 800.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 764.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 762.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 749.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 728.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 722.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 716.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 714.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 713.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 706.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 689.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 680.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 669.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 667.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 657.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 657.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 654.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 649.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 648.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 647.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 630.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 629.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 628.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 618.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 618.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 617.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 614.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 605.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 602.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 599.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 592.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 590.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 586.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 586.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 585.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 580.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 573.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 572.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 570.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 569.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 567.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 567.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 565.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 564.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 561.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 556.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 552.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 550.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 548.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 547.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 543.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 535.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 535.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 531.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 526.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 525.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 523.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 523.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 523.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 522.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 522.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 520.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 519.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 518.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 514.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 512.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 511.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 507.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 506.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 504.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 502.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 498.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 496.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 494.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 488.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 488.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 487.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 487.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 486.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 484.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 484.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 481.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 480.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 478.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 477.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 474.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 473.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 464.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 463.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 459.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 457.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 450.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 445.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 444.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 443.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 438.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 436.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 434.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 429.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 427.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 426.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 424.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 422.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 422.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 420.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 419.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 419.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 416.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 412.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 411.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 411.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 408.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 403.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 400.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 399.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 393.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 392.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 388.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 363.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 362.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 355.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 354.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 350.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 339.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 330.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 327.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 299.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 296.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 260.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 233.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 86.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.8
FF:10158-103A5 76 years, female 86.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.6
Pig sample Sample description nTPM
Midbrain
nTPM: 63.2
Samples: 4

Max nTPM: 72.5
Min nTPM: 50.1
Sample A Female 66.0
Sample B Female 50.1
Sample C Male 72.5
Sample D Male 64.0
Periaqueductal gray
nTPM: 47.3
Samples: 3

Max nTPM: 54.4
Min nTPM: 41.3
Sample B Female 46.2
Sample C Male 54.4
Sample D Male 41.3
Substantia nigra
nTPM: 57.3
Samples: 4

Max nTPM: 77.3
Min nTPM: 37.5
Sample A Female 77.3
Sample B Female 50.5
Sample C Male 64.0
Sample D Male 37.5
Superior colliculi
nTPM: 66.6
Samples: 4

Max nTPM: 89.1
Min nTPM: 49.0
Sample A Female 89.1
Sample B Female 49.0
Sample C Male 74.1
Sample D Male 54.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 266.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.0
Samples: 4

Max nTPM: 294.7
Min nTPM: 238.8
Sample A Male 294.7
Sample B Male 247.1
Sample C Female 238.8
Sample D Female 283.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
75198094 Antisense, RP_060502_01_F10, Mouse strain C57BL/6J (56 days, male) 1.7

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