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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:165.3 nTPM
HPA:165.3 nTPM
GTEx:131.3 nTPM
FANTOM5:128.1 Scaled Tags Per Million
Pig:149.7 nTPM
Mouse:196.1 nTPM
Allen mouse:5.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 165.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 160.8
2586 Male, age 75, left hemisphere 169.0
2666 Male, age 74, left hemisphere 164.7
1870 Female, age 42, unknown 164.2
1827 Male, age 72, unknown 161.5
1833 Male, age 53, unknown 159.6
1830 Male, age 51, unknown 158.7
2019 Male, age 18, unknown 158.6
2411 Female, age 72, unknown 158.6
2828 Female, age 72, unknown 157.6
2219 Male, age 76, both hemispheres 155.6
Dorsal raphe nucleus
nTPM: 163.6
2298 Female, age 72, unknown 167.9
1828 Male, age 53, unknown 165.8
2047 Male, age 72, unknown 163.0
2750 Male, age 76, both hemispheres 161.5
2016 Female, age 72, unknown 159.6
Inferior colliculus
nTPM: 161.9
2097 Female, age 72, unknown 164.1
1848 Female, age 42, unknown 163.1
2849 Male, age 72, unknown 160.4
1890 Male, age 53, unknown 160.1
Median raphe nucleus
nTPM: 162.3
2220 Male, age 76, midline 162.3
Pedunculopontine tegmental nucleus
nTPM: 163.6
2334 Male, age 80, both hemispheres 166.3
2338 Male, age 61, both hemispheres 163.5
1921 Female, age 85, both hemispheres 161.1
Periaquaductal grey, anterior
nTPM: 165.3
1947 Male, age 18, unknown 167.3
2502 Female, age 75, unknown 165.6
1795 Male, age 51, unknown 163.1
Periaquaductal grey, dorsal
nTPM: 160.6
1840 Male, age 53, unknown 165.1
1831 Male, age 72, unknown 160.0
2850 Male, age 76, both hemispheres 159.1
2464 Female, age 72, unknown 158.2
Periaquaductal grey, lateral
nTPM: 158.9
2053 Male, age 18, unknown 159.7
2140 Male, age 76, both hemispheres 158.8
2272 Male, age 74, both hemispheres 158.2
Pretectal area
nTPM: 163.1
1944 Female, age 72, unknown 168.2
1817 Female, age 42, unknown 166.9
1816 Male, age 51, unknown 166.7
2007 Male, age 72, unknown 164.7
2825 Male, age 18, unknown 163.7
2224 Female, age 72, unknown 163.5
1815 Male, age 53, unknown 162.6
2667 Female, age 75, unknown 161.2
2273 Male, age 74, both hemispheres 160.9
2407 Male, age 75, both hemispheres 159.5
2316 Male, age 76, right hemisphere 155.7
Red nucleus
nTPM: 160.5
1821 Female, age 72, unknown 166.4
2584 Male, age 75, left hemisphere 162.0
2725 Female, age 75, unknown 161.5
2588 Male, age 74, left hemisphere 161.3
2227 Male, age 72, unknown 160.7
2785 Male, age 18, unknown 160.4
2503 Female, age 72, unknown 160.3
2769 Male, age 72, unknown 160.0
1954 Female, age 42, unknown 159.9
1865 Male, age 51, unknown 159.6
1904 Male, age 53, unknown 157.6
2823 Male, age 76, right hemisphere 156.0
Substantia nigra
nTPM: 164.9
1916 Female, age 42, unknown 169.5
2241 Male, age 72, unknown 168.3
2665 Male, age 74, both hemispheres 167.1
1851 Male, age 51, unknown 166.8
1941 Male, age 53, unknown 165.9
2590 Female, age 75, unknown 163.7
1889 Female, age 72, unknown 163.1
2699 Male, age 18, unknown 161.9
2583 Male, age 75, right hemisphere 161.6
2409 Female, age 72, unknown 160.8
Superior colliculus
nTPM: 162.5
2664 Male, age 75, both hemispheres 165.4
2087 Female, age 72, unknown 164.8
2587 Male, age 74, left hemisphere 164.4
2261 Male, age 18, unknown 163.8
2668 Female, age 75, unknown 163.7
1796 Male, age 53, unknown 162.7
1839 Male, age 51, unknown 162.5
1895 Male, age 76, right hemisphere 159.7
1995 Male, age 72, unknown 159.2
1913 Female, age 42, unknown 158.5
Ventral tegmental area
nTPM: 163.7
1915 Female, age 42, unknown 167.2
2223 Female, age 72, unknown 165.2
2410 Female, age 72, unknown 165.2
1942 Male, age 51, unknown 163.1
2021 Male, age 53, unknown 161.7
2218 Male, age 76, both hemispheres 159.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 131.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 131.3
Samples: 139

Max nTPM: 242.1
Min nTPM: 82.4
Std nTPM: 23.5
Median nTPM: 129.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 242.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 206.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 204.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 182.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 171.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 169.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 168.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 167.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 167.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 165.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 164.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 163.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 161.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 160.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 159.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 159.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 157.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 155.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 154.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 154.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 154.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 152.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 151.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 151.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 151.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 151.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 150.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 148.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 148.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 147.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 147.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 146.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 146.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 145.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 145.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 144.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 144.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 144.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 141.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 139.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 139.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 138.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 137.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 136.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 136.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 136.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 135.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 135.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 134.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 134.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 133.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 133.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 133.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 133.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 132.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 132.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 132.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 131.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 131.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 131.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 131.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 131.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 131.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 130.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 130.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 130.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 129.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 129.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 129.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 129.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 129.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 129.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 128.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 128.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 128.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 128.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 127.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 126.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 126.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 126.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 126.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 126.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 125.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 124.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 124.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 124.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 123.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 123.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 123.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 123.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 122.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 122.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 121.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 121.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 120.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 120.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 119.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 119.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 119.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 117.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 116.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 116.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 116.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 115.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 115.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 115.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 113.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 112.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 112.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 112.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 111.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 111.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 111.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 109.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 109.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 109.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 109.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 109.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 108.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 108.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 107.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 107.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 106.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 106.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 106.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 105.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 103.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 103.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 102.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 100.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 99.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 97.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 96.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 94.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 93.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 90.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 89.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 82.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 128.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 128.1
FF:10158-103A5 76 years, female 128.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 149.7
Pig sample Sample description nTPM
Midbrain
nTPM: 145.1
Samples: 4

Max nTPM: 191.2
Min nTPM: 111.5
Sample A Female 191.2
Sample B Female 145.7
Sample C Male 131.8
Sample D Male 111.5
Periaqueductal gray
nTPM: 115.7
Samples: 3

Max nTPM: 123.2
Min nTPM: 104.7
Sample B Female 119.3
Sample C Male 123.2
Sample D Male 104.7
Substantia nigra
nTPM: 149.7
Samples: 4

Max nTPM: 199.3
Min nTPM: 115.4
Sample A Female 199.3
Sample B Female 141.8
Sample C Male 142.2
Sample D Male 115.4
Superior colliculi
nTPM: 135.8
Samples: 4

Max nTPM: 160.5
Min nTPM: 123.0
Sample A Female 160.5
Sample B Female 124.1
Sample C Male 135.7
Sample D Male 123.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 196.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 196.1
Samples: 4

Max nTPM: 203.3
Min nTPM: 187.9
Sample A Male 203.3
Sample B Male 187.9
Sample C Female 191.6
Sample D Female 201.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.5
69445415 Antisense, RP_050419_01_B02, Mouse strain C57BL/6J (56 days, male) 7.7
74988744 Antisense, RP_060315_04_B12, Mouse strain C57BL/6J (56 days, male) 3.4

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