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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA004114
Moderate to strong cytoplasmic staining in a subset of immune cells including lung macrophages, placental Hofbauer cells and Kupffer cells in liver. Endothelial cells also showed distinct staining. Remaining tissues were negative.
HPA045134
Strong membranous and cytoplasmic positivity was observed in macrophages. Fibroblasts along with subset of cells in colon, rectum and salivary gland exhibited moderate cytoplasmic staining. Remaining normal tissues were negative.
CAB068203
Alveolar macrophages, Kupffers cells, Hofbauer cells as well as a few other peripheral macrophages showed moderate cytoplasmic positivity. Other normal cells were negative.
The Human Protein Atlas project is funded
