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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA041301
Pigment epithelial cells
Not detected
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
Low
Inner nuclear layer
Not detected
Inner plexiform layer
Not detected
Ganglion cells
Not detected
Nerve fiber layer
Not detected
RETINA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA044239
Pigment epithelial cells
Not detected
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
Not detected
Inner nuclear layer
Not detected
Inner plexiform layer
Not detected
Ganglion cells
Not detected
Nerve fiber layer
Not detected
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 1502.2
Min nTPM: 79.3
Std nTPM: 309.6
Median nTPM:
218_1
71 years, female
1502.2
352_1
62 years, male
1378.2
350_1
84 years, female
1345.6
353_1
82 years, female
1310.9
319_1
81 years, male
1270.8
322_1
76 years, male
1199.3
172_1
72 years, female
1091.4
321_1
62 years, female
1089.4
386_1
76 years, male
1072.8
356_1
87 years, female
1013.4
293_1
68 years, female
1010.5
163_1
78 years, male
959.0
320_1
89 years, female
925.6
354_1
81 years, female
872.9
355_1
70 years, female
858.2
237_1
82 years, male
843.9
6_1
73 years, female
843.6
335_1
73 years, female
822.0
251_1
78 years, male
804.1
286_1
68 years, female
801.8
318_1
68 years, male
790.3
447_1
81 years, male
770.9
243_1
75 years, male
767.0
376_1
75 years, female
761.6
377_1
82 years, female
754.9
292_1
71 years, male
737.2
348_1
84 years, male
734.2
177_1
74 years, male
728.8
405_1
91 years, male
721.9
349_1
83 years, male
716.8
316_1
62 years, male
691.8
425_1
59 years, female
663.1
351_1
91 years, male
652.7
406_1
79 years, male
640.2
311_1
78 years, male
617.0
480_1
63 years, male
600.3
503_1
68 years, male
576.5
229_1
69 years, female
567.1
389_1
86 years, female
554.6
526_1
61 years, male
543.8
384_1
83 years, male
538.0
189_1
76 years, male
531.7
291_1
76 years, male
523.6
375_1
74 years, female
516.1
396_1
62 years, male
505.3
35_1
74 years, female
487.8
246_1
77 years, male
484.8
518_1
75 years, female
480.8
404_1
82 years, female
474.1
153_1
70 years, female
473.6
347_1
72 years, male
473.3
506_1
65 years, male
465.7
99_1
64 years, male
464.6
173_1
67 years, male
464.5
517_1
88 years, male
463.1
317_1
60 years, male
450.2
324_1
76 years, male
443.7
264_1
73 years, female
438.7
379_1
60 years, male
437.8
394_1
75 years, female
436.6
9_1
66 years, female
426.8
468_1
89 years, male
424.5
145_1
84 years, male
413.7
217_1
76 years, male
407.3
2_1
77 years, female
404.3
266_1
85 years, male
403.2
115_1
83 years, male
401.7
495_1
57 years, female
388.4
4_1
88 years, female
383.6
126_1
63 years, male
382.7
265_1
87 years, male
373.9
254_1
77 years, female
354.6
307_1
66 years, female
351.0
117_1
61 years, male
346.6
499_1
55 years, female
341.5
18_1
88 years, male
335.9
295_1
61 years, female
332.3
17_1
71 years, male
325.5
315_1
62 years, female
321.2
139_1
64 years, female
316.4
452_1
88 years, female
313.9
43_1
64 years, female
306.5
81_1
67 years, male
303.8
137_1
83 years, male
299.6
313_1
79 years, female
286.2
120_1
70 years, female
273.1
415_1
77 years, female
250.8
466_1
57 years, female
247.7
109_1
81 years, female
235.6
142_1
61 years, female
235.6
162_1
79 years, female
229.9
32_1
67 years, male
225.0
288_1
66 years, female
217.8
41_1
94 years, female
215.8
119_1
70 years, female
203.2
42_1
85 years, male
192.5
308_1
70 years, female
182.6
149_1
88 years, male
176.6
89_1
63 years, male
174.9
414_1
84 years, female
171.3
490_1
67 years, female
149.8
314_1
67 years, male
145.8
501_1
88 years, male
119.2
491_1
89 years, female
112.4
413_1
59 years, female
79.3
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.