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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:73.2 nTPM
HPA:73.2 nTPM
GTEx:85.3 nTPM
FANTOM5:69.5 Scaled Tags Per Million
Pig:85.7 nTPM
Mouse:191.5 nTPM
Allen mouse:1.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 73.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.5
2411 Female, age 72, unknown 70.1
2666 Male, age 74, left hemisphere 68.3
1827 Male, age 72, unknown 65.3
1830 Male, age 51, unknown 63.4
1833 Male, age 53, unknown 62.9
2219 Male, age 76, both hemispheres 60.8
2828 Female, age 72, unknown 60.3
2019 Male, age 18, unknown 58.7
1870 Female, age 42, unknown 58.1
2586 Male, age 75, left hemisphere 57.5
Dorsal raphe nucleus
nTPM: 68.0
2298 Female, age 72, unknown 74.9
2047 Male, age 72, unknown 68.1
2016 Female, age 72, unknown 67.5
2750 Male, age 76, both hemispheres 66.2
1828 Male, age 53, unknown 63.4
Inferior colliculus
nTPM: 62.0
2097 Female, age 72, unknown 64.2
1848 Female, age 42, unknown 61.6
2849 Male, age 72, unknown 61.3
1890 Male, age 53, unknown 61.0
Median raphe nucleus
nTPM: 66.4
2220 Male, age 76, midline 66.4
Pedunculopontine tegmental nucleus
nTPM: 68.3
2338 Male, age 61, both hemispheres 76.4
2334 Male, age 80, both hemispheres 65.8
1921 Female, age 85, both hemispheres 62.7
Periaquaductal grey, anterior
nTPM: 66.3
2502 Female, age 75, unknown 71.3
1947 Male, age 18, unknown 64.3
1795 Male, age 51, unknown 63.3
Periaquaductal grey, dorsal
nTPM: 60.8
2850 Male, age 76, both hemispheres 62.4
1840 Male, age 53, unknown 61.2
2464 Female, age 72, unknown 61.1
1831 Male, age 72, unknown 58.4
Periaquaductal grey, lateral
nTPM: 73.2
2272 Male, age 74, both hemispheres 90.4
2053 Male, age 18, unknown 66.7
2140 Male, age 76, both hemispheres 62.7
Pretectal area
nTPM: 65.7
2273 Male, age 74, both hemispheres 77.0
2224 Female, age 72, unknown 72.6
1944 Female, age 72, unknown 72.1
1817 Female, age 42, unknown 70.9
2007 Male, age 72, unknown 68.0
1816 Male, age 51, unknown 65.4
2825 Male, age 18, unknown 63.3
1815 Male, age 53, unknown 60.6
2316 Male, age 76, right hemisphere 60.4
2667 Female, age 75, unknown 56.5
2407 Male, age 75, both hemispheres 56.0
Red nucleus
nTPM: 62.0
1954 Female, age 42, unknown 66.6
1821 Female, age 72, unknown 65.6
2503 Female, age 72, unknown 65.3
2725 Female, age 75, unknown 64.6
1865 Male, age 51, unknown 63.5
2823 Male, age 76, right hemisphere 63.3
1904 Male, age 53, unknown 61.8
2785 Male, age 18, unknown 61.8
2769 Male, age 72, unknown 60.5
2227 Male, age 72, unknown 57.9
2588 Male, age 74, left hemisphere 56.8
2584 Male, age 75, left hemisphere 55.9
Substantia nigra
nTPM: 66.0
2409 Female, age 72, unknown 79.0
1916 Female, age 42, unknown 75.2
1941 Male, age 53, unknown 67.1
2590 Female, age 75, unknown 66.9
1851 Male, age 51, unknown 66.5
2699 Male, age 18, unknown 66.0
2241 Male, age 72, unknown 64.3
1889 Female, age 72, unknown 61.4
2665 Male, age 74, both hemispheres 57.3
2583 Male, age 75, right hemisphere 55.9
Superior colliculus
nTPM: 62.5
2261 Male, age 18, unknown 66.8
2087 Female, age 72, unknown 65.1
1796 Male, age 53, unknown 63.8
2587 Male, age 74, left hemisphere 63.7
2668 Female, age 75, unknown 63.6
1995 Male, age 72, unknown 63.5
1913 Female, age 42, unknown 62.9
1839 Male, age 51, unknown 60.5
1895 Male, age 76, right hemisphere 59.1
2664 Male, age 75, both hemispheres 56.2
Ventral tegmental area
nTPM: 67.7
2410 Female, age 72, unknown 82.5
2223 Female, age 72, unknown 68.5
2021 Male, age 53, unknown 65.3
1915 Female, age 42, unknown 64.6
2218 Male, age 76, both hemispheres 64.2
1942 Male, age 51, unknown 60.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 85.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 85.3
Samples: 139

Max nTPM: 166.3
Min nTPM: 48.7
Std nTPM: 18.2
Median nTPM: 82.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 166.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 145.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 137.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 132.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 127.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 124.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 124.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 117.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 116.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 115.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 114.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 113.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 111.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 107.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 106.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 106.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 105.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 103.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 103.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 103.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 101.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 101.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 99.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 98.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 98.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 97.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 97.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 96.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 96.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 95.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 94.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 94.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 93.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 93.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 92.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 92.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 92.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 91.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 90.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 90.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 90.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 89.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 89.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 88.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 88.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 88.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 87.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 87.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 87.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 87.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 86.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 85.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 85.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 85.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 85.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 85.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 85.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 84.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 84.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 83.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 83.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 83.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 82.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 82.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 82.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 81.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 81.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 81.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 80.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 80.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 80.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 80.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 80.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 80.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 80.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 79.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 79.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 79.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 78.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 78.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 78.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 78.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 78.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 78.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 78.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 77.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 77.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 77.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 76.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 76.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 76.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 76.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 75.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 74.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 73.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 72.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 72.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 71.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 71.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 70.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 70.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 70.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 70.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 70.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 70.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 69.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 69.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 68.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 68.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 68.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 67.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 67.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 66.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 66.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 66.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 65.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 65.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 64.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 64.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 64.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 63.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 62.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 60.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 58.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 58.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 53.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 48.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 69.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 69.5
FF:10158-103A5 76 years, female 69.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 85.7
Pig sample Sample description nTPM
Midbrain
nTPM: 81.3
Samples: 4

Max nTPM: 105.7
Min nTPM: 63.4
Sample A Female 105.7
Sample B Female 75.9
Sample C Male 80.2
Sample D Male 63.4
Periaqueductal gray
nTPM: 61.8
Samples: 3

Max nTPM: 69.5
Min nTPM: 51.6
Sample B Female 64.3
Sample C Male 69.5
Sample D Male 51.6
Substantia nigra
nTPM: 80.0
Samples: 4

Max nTPM: 117.3
Min nTPM: 53.3
Sample A Female 117.3
Sample B Female 67.3
Sample C Male 82.2
Sample D Male 53.3
Superior colliculi
nTPM: 85.7
Samples: 4

Max nTPM: 103.4
Min nTPM: 70.9
Sample A Female 103.4
Sample B Female 74.4
Sample C Male 94.1
Sample D Male 70.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 191.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 191.5
Samples: 4

Max nTPM: 208.3
Min nTPM: 169.7
Sample A Male 204.0
Sample B Male 183.9
Sample C Female 169.7
Sample D Female 208.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.1
634449 Antisense, RP_040907_02_H10, Mouse strain C57BL/6J (56 days, male) 1.1

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