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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 250.8
Min nTPM: 35.6
Std nTPM: 44.8
Median nTPM:
447_1
81 years, male
250.8
389_1
86 years, female
234.8
406_1
79 years, male
233.0
490_1
67 years, female
222.8
9_1
66 years, female
222.1
163_1
78 years, male
210.2
396_1
62 years, male
208.5
480_1
63 years, male
208.1
172_1
72 years, female
196.2
468_1
89 years, male
194.7
394_1
75 years, female
189.0
126_1
63 years, male
188.4
503_1
68 years, male
182.7
319_1
81 years, male
181.5
291_1
76 years, male
180.9
189_1
76 years, male
179.4
149_1
88 years, male
179.1
466_1
57 years, female
178.2
356_1
87 years, female
176.3
526_1
61 years, male
174.5
499_1
55 years, female
171.6
413_1
59 years, female
169.3
415_1
77 years, female
166.8
517_1
88 years, male
165.6
347_1
72 years, male
164.1
349_1
83 years, male
162.1
352_1
62 years, male
161.2
335_1
73 years, female
160.6
414_1
84 years, female
158.8
217_1
76 years, male
158.6
246_1
77 years, male
156.4
376_1
75 years, female
155.3
404_1
82 years, female
152.8
354_1
81 years, female
152.3
321_1
62 years, female
146.8
353_1
82 years, female
145.0
405_1
91 years, male
144.9
177_1
74 years, male
143.2
377_1
82 years, female
142.8
286_1
68 years, female
141.7
292_1
71 years, male
141.1
218_1
71 years, female
139.9
318_1
68 years, male
138.3
254_1
77 years, female
137.4
316_1
62 years, male
134.3
425_1
59 years, female
133.4
32_1
67 years, male
132.6
384_1
83 years, male
132.0
495_1
57 years, female
130.9
324_1
76 years, male
128.7
99_1
64 years, male
127.5
355_1
70 years, female
127.3
350_1
84 years, female
126.5
251_1
78 years, male
124.6
314_1
67 years, male
123.7
115_1
83 years, male
122.8
518_1
75 years, female
122.4
293_1
68 years, female
121.6
117_1
61 years, male
120.7
288_1
66 years, female
119.9
320_1
89 years, female
119.4
311_1
78 years, male
119.3
265_1
87 years, male
119.0
243_1
75 years, male
118.4
153_1
70 years, female
117.9
42_1
85 years, male
117.6
137_1
83 years, male
113.8
142_1
61 years, female
112.7
237_1
82 years, male
110.7
317_1
60 years, male
109.7
501_1
88 years, male
109.2
386_1
76 years, male
108.9
162_1
79 years, female
107.8
351_1
91 years, male
106.3
89_1
63 years, male
105.7
81_1
67 years, male
104.6
264_1
73 years, female
104.1
295_1
61 years, female
102.4
315_1
62 years, female
102.2
375_1
74 years, female
101.5
145_1
84 years, male
101.1
229_1
69 years, female
101.0
307_1
66 years, female
96.1
6_1
73 years, female
96.0
491_1
89 years, female
92.2
313_1
79 years, female
92.1
109_1
81 years, female
90.9
266_1
85 years, male
87.5
18_1
88 years, male
85.3
506_1
65 years, male
85.2
35_1
74 years, female
81.4
119_1
70 years, female
78.0
348_1
84 years, male
76.8
4_1
88 years, female
75.5
379_1
60 years, male
71.0
41_1
94 years, female
69.9
43_1
64 years, female
68.1
2_1
77 years, female
64.9
452_1
88 years, female
62.5
139_1
64 years, female
59.9
322_1
76 years, male
57.1
17_1
71 years, male
56.0
173_1
67 years, male
54.6
120_1
70 years, female
54.4
308_1
70 years, female
35.6
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
