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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:56.0 nTPM
HPA:56.0 nTPM
GTEx:54.9 nTPM
FANTOM5:372.4 Scaled Tags Per Million
Pig:79.2 nTPM
Mouse:157.3 nTPM
Allen mouse:17.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 56.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 52.9
2411 Female, age 72, unknown 57.8
2019 Male, age 18, unknown 57.7
1870 Female, age 42, unknown 57.3
1827 Male, age 72, unknown 54.0
2586 Male, age 75, left hemisphere 53.6
2828 Female, age 72, unknown 52.4
1830 Male, age 51, unknown 51.7
1833 Male, age 53, unknown 49.9
2666 Male, age 74, left hemisphere 49.5
2219 Male, age 76, both hemispheres 45.4
Dorsal raphe nucleus
nTPM: 47.9
2750 Male, age 76, both hemispheres 53.3
2016 Female, age 72, unknown 49.1
1828 Male, age 53, unknown 48.9
2298 Female, age 72, unknown 44.5
2047 Male, age 72, unknown 43.5
Inferior colliculus
nTPM: 48.0
1890 Male, age 53, unknown 50.4
2097 Female, age 72, unknown 48.9
1848 Female, age 42, unknown 47.9
2849 Male, age 72, unknown 44.7
Median raphe nucleus
nTPM: 47.0
2220 Male, age 76, midline 47.0
Pedunculopontine tegmental nucleus
nTPM: 47.6
2334 Male, age 80, both hemispheres 52.4
1921 Female, age 85, both hemispheres 48.7
2338 Male, age 61, both hemispheres 41.7
Periaquaductal grey, anterior
nTPM: 50.5
2502 Female, age 75, unknown 55.5
1947 Male, age 18, unknown 50.1
1795 Male, age 51, unknown 45.8
Periaquaductal grey, dorsal
nTPM: 46.3
1831 Male, age 72, unknown 50.3
2464 Female, age 72, unknown 49.2
2850 Male, age 76, both hemispheres 44.6
1840 Male, age 53, unknown 40.9
Periaquaductal grey, lateral
nTPM: 44.5
2053 Male, age 18, unknown 49.4
2140 Male, age 76, both hemispheres 42.1
2272 Male, age 74, both hemispheres 42.0
Pretectal area
nTPM: 53.2
1816 Male, age 51, unknown 61.1
1815 Male, age 53, unknown 58.6
1944 Female, age 72, unknown 57.9
2007 Male, age 72, unknown 57.2
2273 Male, age 74, both hemispheres 55.2
1817 Female, age 42, unknown 55.1
2316 Male, age 76, right hemisphere 49.2
2407 Male, age 75, both hemispheres 49.1
2825 Male, age 18, unknown 48.2
2667 Female, age 75, unknown 47.8
2224 Female, age 72, unknown 46.1
Red nucleus
nTPM: 56.0
1865 Male, age 51, unknown 65.3
1821 Female, age 72, unknown 64.0
1904 Male, age 53, unknown 61.2
2503 Female, age 72, unknown 60.9
2785 Male, age 18, unknown 59.3
1954 Female, age 42, unknown 55.6
2588 Male, age 74, left hemisphere 54.9
2769 Male, age 72, unknown 54.2
2227 Male, age 72, unknown 54.0
2823 Male, age 76, right hemisphere 50.9
2725 Female, age 75, unknown 47.7
2584 Male, age 75, left hemisphere 44.3
Substantia nigra
nTPM: 48.2
1889 Female, age 72, unknown 55.9
2409 Female, age 72, unknown 53.4
2583 Male, age 75, right hemisphere 51.4
2590 Female, age 75, unknown 51.2
1941 Male, age 53, unknown 48.8
1851 Male, age 51, unknown 47.0
2241 Male, age 72, unknown 46.2
2665 Male, age 74, both hemispheres 44.7
2699 Male, age 18, unknown 41.9
1916 Female, age 42, unknown 41.4
Superior colliculus
nTPM: 54.9
1913 Female, age 42, unknown 64.8
2668 Female, age 75, unknown 60.2
1995 Male, age 72, unknown 58.7
2587 Male, age 74, left hemisphere 56.2
2261 Male, age 18, unknown 53.4
1895 Male, age 76, right hemisphere 52.8
2664 Male, age 75, both hemispheres 52.6
2087 Female, age 72, unknown 52.3
1796 Male, age 53, unknown 50.9
1839 Male, age 51, unknown 47.3
Ventral tegmental area
nTPM: 46.7
2410 Female, age 72, unknown 51.5
2223 Female, age 72, unknown 50.3
1942 Male, age 51, unknown 45.6
2021 Male, age 53, unknown 44.8
2218 Male, age 76, both hemispheres 44.6
1915 Female, age 42, unknown 43.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 54.9
Samples: 139

Max nTPM: 116.2
Min nTPM: 24.3
Std nTPM: 17.5
Median nTPM: 51.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 116.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 106.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 101.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 99.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 99.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 94.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 93.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 92.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 87.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 86.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 86.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 82.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 81.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 79.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 76.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 75.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 75.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 75.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 73.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 72.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 71.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 71.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 71.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 71.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 70.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 66.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 65.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 65.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 64.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 64.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 63.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 63.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 63.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 63.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 62.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 61.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 60.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 60.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 59.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 59.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 58.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 57.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 57.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 57.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 56.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 56.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 56.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 55.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 55.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 55.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 55.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 55.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 55.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 54.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 54.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 54.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 53.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 53.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 52.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 52.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 51.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 51.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 50.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 50.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 50.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 50.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 49.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 49.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 49.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 48.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 48.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 48.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 48.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 47.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 47.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 47.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 47.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 47.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 47.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 47.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 46.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 46.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 46.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 45.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 44.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 44.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 44.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 44.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 44.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 43.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 43.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 42.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 42.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 41.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 41.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 41.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 41.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 40.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 40.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 40.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 38.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 38.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 37.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 37.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 37.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 37.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 36.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 36.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 35.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 35.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 35.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 34.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 34.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 34.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 34.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 33.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 32.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 32.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 31.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 30.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 29.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 25.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 24.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 372.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 372.4
FF:10158-103A5 76 years, female 372.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 79.2
Pig sample Sample description nTPM
Midbrain
nTPM: 79.2
Samples: 4

Max nTPM: 84.5
Min nTPM: 76.1
Sample A Female 84.5
Sample B Female 76.1
Sample C Male 79.9
Sample D Male 76.4
Periaqueductal gray
nTPM: 66.6
Samples: 3

Max nTPM: 70.9
Min nTPM: 64.4
Sample B Female 70.9
Sample C Male 64.4
Sample D Male 64.4
Substantia nigra
nTPM: 66.3
Samples: 4

Max nTPM: 70.7
Min nTPM: 59.1
Sample A Female 70.0
Sample B Female 59.1
Sample C Male 65.5
Sample D Male 70.7
Superior colliculi
nTPM: 69.4
Samples: 4

Max nTPM: 76.4
Min nTPM: 50.1
Sample A Female 75.2
Sample B Female 50.1
Sample C Male 76.4
Sample D Male 76.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 157.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 157.3
Samples: 4

Max nTPM: 162.8
Min nTPM: 143.8
Sample A Male 143.8
Sample B Male 162.7
Sample C Female 162.8
Sample D Female 159.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 17.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.8
70302246 Antisense, RP_050607_03_H09, Mouse strain C57BL/6J (56 days, male) 17.8

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