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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.7 nTPM
HPA:155.7 nTPM
GTEx:243.0 nTPM
FANTOM5:172.4 Scaled Tags Per Million
Pig:43.1 nTPM
Mouse:42.9 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 130.1
1833 Male, age 53, unknown 141.4
2586 Male, age 75, left hemisphere 139.0
1870 Female, age 42, unknown 136.0
2828 Female, age 72, unknown 132.6
1830 Male, age 51, unknown 131.8
2411 Female, age 72, unknown 130.5
1827 Male, age 72, unknown 127.2
2666 Male, age 74, left hemisphere 126.0
2219 Male, age 76, both hemispheres 122.1
2019 Male, age 18, unknown 114.0
Dorsal raphe nucleus
nTPM: 154.1
2047 Male, age 72, unknown 164.2
1828 Male, age 53, unknown 157.8
2016 Female, age 72, unknown 157.5
2298 Female, age 72, unknown 155.3
2750 Male, age 76, both hemispheres 135.8
Inferior colliculus
nTPM: 147.9
1848 Female, age 42, unknown 155.8
2849 Male, age 72, unknown 148.1
1890 Male, age 53, unknown 145.1
2097 Female, age 72, unknown 142.8
Median raphe nucleus
nTPM: 151.7
2220 Male, age 76, midline 151.7
Pedunculopontine tegmental nucleus
nTPM: 154.9
2338 Male, age 61, both hemispheres 184.2
2334 Male, age 80, both hemispheres 144.1
1921 Female, age 85, both hemispheres 136.5
Periaquaductal grey, anterior
nTPM: 140.1
1947 Male, age 18, unknown 148.6
1795 Male, age 51, unknown 142.1
2502 Female, age 75, unknown 129.4
Periaquaductal grey, dorsal
nTPM: 155.7
2850 Male, age 76, both hemispheres 176.2
1840 Male, age 53, unknown 157.5
2464 Female, age 72, unknown 146.8
1831 Male, age 72, unknown 142.2
Periaquaductal grey, lateral
nTPM: 152.3
2272 Male, age 74, both hemispheres 158.3
2140 Male, age 76, both hemispheres 155.6
2053 Male, age 18, unknown 143.1
Pretectal area
nTPM: 139.8
2224 Female, age 72, unknown 155.6
2273 Male, age 74, both hemispheres 152.9
2825 Male, age 18, unknown 150.3
2667 Female, age 75, unknown 149.2
1817 Female, age 42, unknown 145.1
1944 Female, age 72, unknown 139.5
2316 Male, age 76, right hemisphere 134.3
2407 Male, age 75, both hemispheres 132.9
1815 Male, age 53, unknown 130.0
1816 Male, age 51, unknown 129.1
2007 Male, age 72, unknown 119.5
Red nucleus
nTPM: 138.8
1821 Female, age 72, unknown 151.1
1954 Female, age 42, unknown 150.8
2725 Female, age 75, unknown 148.9
2503 Female, age 72, unknown 145.0
1865 Male, age 51, unknown 141.9
1904 Male, age 53, unknown 141.5
2227 Male, age 72, unknown 141.5
2823 Male, age 76, right hemisphere 138.2
2769 Male, age 72, unknown 138.1
2584 Male, age 75, left hemisphere 126.6
2785 Male, age 18, unknown 121.2
2588 Male, age 74, left hemisphere 120.8
Substantia nigra
nTPM: 149.8
2699 Male, age 18, unknown 198.3
2241 Male, age 72, unknown 165.9
1916 Female, age 42, unknown 157.8
1851 Male, age 51, unknown 151.6
2409 Female, age 72, unknown 149.4
1889 Female, age 72, unknown 147.0
2590 Female, age 75, unknown 138.7
1941 Male, age 53, unknown 132.6
2583 Male, age 75, right hemisphere 129.3
2665 Male, age 74, both hemispheres 127.6
Superior colliculus
nTPM: 135.0
1995 Male, age 72, unknown 146.3
2087 Female, age 72, unknown 142.0
2261 Male, age 18, unknown 140.9
1796 Male, age 53, unknown 137.8
1913 Female, age 42, unknown 132.9
2668 Female, age 75, unknown 132.7
2587 Male, age 74, left hemisphere 131.0
1839 Male, age 51, unknown 130.9
2664 Male, age 75, both hemispheres 130.9
1895 Male, age 76, right hemisphere 125.1
Ventral tegmental area
nTPM: 144.0
1915 Female, age 42, unknown 153.4
2218 Male, age 76, both hemispheres 145.1
1942 Male, age 51, unknown 143.9
2410 Female, age 72, unknown 142.2
2021 Male, age 53, unknown 142.0
2223 Female, age 72, unknown 137.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 243.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 243.0
Samples: 139

Max nTPM: 1084.0
Min nTPM: 11.7
Std nTPM: 180.7
Median nTPM: 190.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1084.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 818.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 800.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 777.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 739.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 714.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 681.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 632.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 598.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 596.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 571.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 524.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 493.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 472.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 455.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 451.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 425.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 414.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 400.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 386.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 363.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 357.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 346.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 346.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 335.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 332.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 331.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 327.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 321.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 316.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 313.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 307.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 303.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 302.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 302.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 301.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 298.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 297.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 293.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 286.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 285.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 283.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 276.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 275.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 269.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 266.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 264.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 258.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 257.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 257.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 254.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 254.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 242.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 242.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 239.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 239.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 233.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 226.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 224.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 210.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 206.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 203.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 202.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 198.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 195.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 195.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 195.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 194.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 193.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 190.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 189.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 187.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 186.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 185.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 183.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 181.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 179.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 177.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 174.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 171.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 170.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 169.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 166.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 164.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 162.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 159.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 159.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 155.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 154.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 153.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 153.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 148.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 141.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 139.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 138.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 137.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 136.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 136.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 136.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 134.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 134.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 134.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 133.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 131.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 130.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 129.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 125.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 124.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 116.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 116.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 116.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 115.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 111.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 104.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 101.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 99.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 98.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 95.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 93.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 90.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 87.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 84.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 78.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 75.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 71.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 69.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 68.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 66.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 63.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 58.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 47.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 39.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 35.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 33.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 31.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 24.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 172.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 172.4
FF:10158-103A5 76 years, female 172.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.1
Pig sample Sample description nTPM
Midbrain
nTPM: 36.0
Samples: 4

Max nTPM: 45.7
Min nTPM: 27.5
Sample A Female 38.2
Sample B Female 45.7
Sample C Male 32.4
Sample D Male 27.5
Periaqueductal gray
nTPM: 43.1
Samples: 3

Max nTPM: 45.5
Min nTPM: 39.9
Sample B Female 45.5
Sample C Male 43.9
Sample D Male 39.9
Substantia nigra
nTPM: 35.2
Samples: 4

Max nTPM: 41.9
Min nTPM: 31.1
Sample A Female 41.9
Sample B Female 35.2
Sample C Male 32.5
Sample D Male 31.1
Superior colliculi
nTPM: 34.8
Samples: 4

Max nTPM: 39.3
Min nTPM: 31.2
Sample A Female 39.3
Sample B Female 31.2
Sample C Male 35.6
Sample D Male 33.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 42.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 42.9
Samples: 4

Max nTPM: 46.0
Min nTPM: 41.1
Sample A Male 46.0
Sample B Male 43.1
Sample C Female 41.5
Sample D Female 41.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
68269646 Antisense, RP_041129_02_A02, Mouse strain C57BL/6J (56 days, male) 0.0

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