Expression of TMSB10 in glioma - The Human Protein Atlas

GLIOMA - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

TMSB10 is not prognostic in glioma

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 1745.87

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

2148.3

Number of samples

153

Samples

Sample	Description	FPKM
TCGA-27-2524-01A	56 years, male, white, dead, 231 days	7414.5
TCGA-27-1831-01A	66 years, male, white, dead, 505 days	6247.0
TCGA-14-1829-01A	57 years, male, black or african american, alive, 218 days	6028.6
TCGA-06-0139-01A	40 years, male, white, dead, 362 days	5141.0
TCGA-76-4928-01B	85 years, female, white, dead, 94 days	4751.4
TCGA-02-0055-01A	62 years, female, white, dead, 76 days	4538.4
TCGA-12-3652-01A	60 years, male, white, dead, 1062 days	4525.3
TCGA-06-0178-01A	39 years, male, white, dead, 2681 days	4222.8
TCGA-28-5218-01A	63 years, male, white, dead, 157 days	4204.8
TCGA-06-0219-01A	67 years, male, white, dead, 22 days	4029.6
TCGA-06-0644-01A	71 years, male, black or african american, dead, 384 days	4010.1
TCGA-19-4065-01A	36 years, male, white, alive, 214 days	3994.4
TCGA-32-5222-01A	66 years, male, white, dead, 585 days	3938.6
TCGA-14-0817-01A	69 years, female, white, dead, 164 days	3855.7
TCGA-06-5418-01A	75 years, female, white, dead, 83 days	3844.4
TCGA-06-5416-01A	23 years, female, white, alive, 204 days	3767.0
TCGA-02-2486-01A	64 years, male, white, dead, 618 days	3696.4
TCGA-06-0238-01A	46 years, male, white, dead, 405 days	3521.0
TCGA-12-5299-01A	56 years, female, white, dead, 98 days	3516.0
TCGA-06-0141-01A	62 years, male, white, dead, 313 days	3442.3
TCGA-06-5411-01A	51 years, male, white, dead, 254 days	3387.0
TCGA-06-5412-01A	78 years, female, white, dead, 138 days	3248.7
TCGA-12-5295-01A	60 years, female, white, dead, 454 days	3049.5
TCGA-12-0616-01A	36 years, female, white, dead, 448 days	3044.4
TCGA-32-4213-01A	47 years, female, white, alive, 604 days	3040.8
TCGA-28-2509-01A	77 years, female, white, alive, 145 days	3026.5
TCGA-27-2519-01A	48 years, male, white, dead, 550 days	3008.2
TCGA-14-0787-01A	69 years, male, asian, dead, 68 days	3004.8
TCGA-14-2554-01A	52 years, female, white, dead, 532 days	2959.8
TCGA-06-0138-01A	43 years, male, white, dead, 737 days	2855.2
TCGA-28-5213-01A	72 years, male, white, alive, 951 days	2844.2
TCGA-12-3650-01A	46 years, male, white, dead, 333 days	2820.8
TCGA-12-1597-01B	62 years, female, white, dead, 675 days	2803.8
TCGA-06-0750-01A	43 years, male, white, dead, 28 days	2778.8
TCGA-32-1982-01A	76 years, female, white, dead, 142 days	2717.3
TCGA-06-0210-01A	72 years, female, white, dead, 225 days	2709.5
TCGA-06-0190-01A	62 years, male, white, dead, 317 days	2679.4
TCGA-06-0132-01A	49 years, male, white, dead, 771 days	2601.1
TCGA-14-1823-01A	58 years, female, white, dead, 543 days	2598.1
TCGA-27-2523-01A	63 years, male, white, dead, 489 days	2587.7
TCGA-28-2513-01A	69 years, female, white, alive, 222 days	2586.9
TCGA-06-0744-01A	67 years, male, white, dead, 1426 days	2578.6
TCGA-06-0745-01A	59 years, male, white, dead, 239 days	2539.8
TCGA-28-5216-01A	52 years, male, white, alive, 415 days	2461.4
TCGA-02-2483-01A	43 years, male, asian, alive, 466 days	2461.2
TCGA-06-5410-01A	72 years, female, white, dead, 108 days	2455.1
TCGA-06-2562-01A	81 years, male, white, dead, 382 days	2432.5
TCGA-14-0781-01B	49 years, male, black or african american, dead, 29 days	2422.7
TCGA-41-2572-01A	67 years, male, white, dead, 406 days	2416.9
TCGA-12-0821-01A	62 years, male, white, dead, 323 days	2389.3
TCGA-27-2526-01A	79 years, female, white, dead, 87 days	2353.5
TCGA-32-1980-01A	72 years, male, white, dead, 36 days	2347.8
TCGA-15-0742-01A	65 years, male, white, dead, 419 days	2321.7
TCGA-19-1787-01B	49 years, male, white, dead, 385 days	2311.3
TCGA-06-0649-01B	73 years, female, black or african american, dead, 64 days	2289.5
TCGA-06-5413-01A	67 years, male, white, alive, 268 days	2282.7
TCGA-27-1832-01A	59 years, female, white, dead, 300 days	2261.4
TCGA-41-3915-01A	48 years, male, white, dead, 360 days	2254.1
TCGA-06-0184-01A	63 years, male, white, dead, 2126 days	2239.7
TCGA-06-0645-01A	56 years, female, white, dead, 175 days	2215.4
TCGA-06-0156-01A	57 years, male, white, dead, 178 days	2154.6
TCGA-06-2559-01A	83 years, male, white, dead, 150 days	2092.7
TCGA-06-0749-01A	50 years, male, black or african american, dead, 82 days	2063.5
TCGA-06-2558-01A	75 years, female, white, dead, 380 days	2054.5
TCGA-27-2528-01A	62 years, male, white, dead, 480 days	2052.1
TCGA-06-0686-01A	53 years, male, white, dead, 432 days	2019.2
TCGA-06-0174-01A	54 years, male, white, dead, 98 days	2017.8
TCGA-28-5208-01A	52 years, male, white, dead, 544 days	2001.7
TCGA-41-2571-01A	89 years, male, white, dead, 26 days	1967.5
TCGA-26-5135-01A	72 years, female, white, dead, 270 days	1930.8
TCGA-76-4932-01A	50 years, female, white, dead, 1458 days	1928.9
TCGA-06-0168-01A	59 years, female, white, dead, 598 days	1923.3
TCGA-06-5414-01A	61 years, male, white, alive, 273 days	1917.1
TCGA-12-0618-01A	49 years, male, white, dead, 395 days	1911.2
TCGA-06-2569-01A	24 years, female, black or african american, alive, 13 days	1885.9
TCGA-76-4926-01B	68 years, male, white, dead, 138 days	1879.1
TCGA-06-0211-01B	47 years, male, white, dead, 360 days	1878.3
TCGA-76-4927-01A	58 years, male, white, dead, 535 days	1869.4
TCGA-16-0846-01A	85 years, male, white, dead, 119 days	1860.6
TCGA-28-5220-01A	67 years, male, white, dead, 388 days	1835.7
TCGA-06-0130-01A	54 years, male, white, dead, 394 days	1833.3
TCGA-14-0789-01A	54 years, male, white, dead, 342 days	1831.2
TCGA-28-2499-01A	59 years, male, white, dead, 95 days	1816.9
TCGA-26-5136-01B	78 years, female, white, dead, 577 days	1785.2
TCGA-27-1837-01A	36 years, male, white, dead, 427 days	1760.2
TCGA-76-4925-01A	76 years, male, white, dead, 146 days	1758.7
TCGA-06-0747-01A	53 years, male, white, dead, 82 days	1752.9
TCGA-27-1830-01A	57 years, male, white, dead, 154 days	1751.3
TCGA-32-2615-01A	62 years, male, white, dead, 485 days	1751.0
TCGA-16-1045-01B	49 years, female, white, dead, 883 days	1740.7
TCGA-19-2624-01A	51 years, male, white, dead, 5 days	1738.5
TCGA-06-2563-01A	72 years, female, white, alive, 932 days	1715.1
TCGA-28-5204-01A	72 years, male, white, dead, 454 days	1712.2
TCGA-02-2485-01A	53 years, male, black or african american, alive, 470 days	1693.9
TCGA-19-2625-01A	76 years, female, white, dead, 124 days	1673.0
TCGA-27-2521-01A	34 years, male, white, dead, 510 days	1659.3
TCGA-28-1753-01A	53 years, male, white, alive, 37 days	1632.2
TCGA-06-0878-01A	74 years, male, white, alive, 218 days	1615.4
TCGA-26-5139-01A	65 years, female, white, alive, 48 days	1605.1
TCGA-06-0882-01A	30 years, male, white, dead, 632 days	1604.3
TCGA-06-5858-01A	45 years, female, white, alive, 187 days	1596.6
TCGA-41-4097-01A	63 years, female, white, dead, 6 days	1591.4
TCGA-06-5408-01A	54 years, female, white, dead, 357 days	1567.3
TCGA-06-2565-01A	59 years, male, asian, dead, 506 days	1557.6
TCGA-32-2616-01A	48 years, female, white, dead, 224 days	1553.4
TCGA-12-0619-01A	60 years, male, white, dead, 1062 days	1512.2
TCGA-06-0743-01A	69 years, male, white, dead, 803 days	1503.7
TCGA-76-4931-01A	70 years, female, white, dead, 279 days	1498.3
TCGA-06-0646-01A	61 years, male, white, dead, 175 days	1478.2
TCGA-28-5207-01A	71 years, male, white, dead, 343 days	1448.3
TCGA-14-1825-01A	70 years, male, white, dead, 232 days	1444.3
TCGA-06-2570-01A	21 years, female, white, alive, 958 days	1426.5
TCGA-32-2632-01A	80 years, male, white, dead, 269 days	1419.7
TCGA-06-2561-01A	53 years, female, white, dead, 537 days	1418.7
TCGA-32-2638-01A	67 years, male, white, dead, 766 days	1391.3
TCGA-06-0187-01A	69 years, male, white, dead, 828 days	1363.0
TCGA-14-0871-01A	75 years, female, white, dead, 880 days	1334.6
TCGA-27-1834-01A	56 years, male, white, dead, 1233 days	1333.4
TCGA-32-2634-01A	82 years, male, white, alive, 693 days	1292.1
TCGA-19-2629-01A	60 years, male, white, dead, 737 days	1289.7
TCGA-12-3653-01A	34 years, female, white, dead, 442 days	1261.1
TCGA-28-5209-01A	66 years, female, white, alive, 77 days	1259.6
TCGA-02-0047-01A	78 years, male, white, dead, 448 days	1257.2
TCGA-28-2514-01A	45 years, male, asian, alive, 160 days	1246.8
TCGA-41-5651-01A	59 years, female, black or african american, dead, 460 days	1232.8
TCGA-06-0125-01A	63 years, female, white, dead, 1448 days	1230.4
TCGA-28-1747-01C	44 years, male, white, dead, 77 days	1228.3
TCGA-76-4929-01A	76 years, female, white, dead, 111 days	1196.1
TCGA-06-5856-01A	58 years, male, white, dead, 114 days	1175.7
TCGA-26-5133-01A	59 years, male, white, alive, 452 days	1163.9
TCGA-14-1034-01A	60 years, female, dead, 485 days	1163.7
TCGA-06-2564-01A	50 years, male, white, alive, 181 days	1121.4
TCGA-26-5134-01A	74 years, male, white, alive, 167 days	1118.3
TCGA-19-2620-01A	70 years, male, white, dead, 148 days	1084.4
TCGA-26-5132-01A	74 years, male, white, alive, 286 days	1083.4
TCGA-28-5215-01A	62 years, female, white, dead, 335 days	1056.5
TCGA-06-2557-01A	76 years, male, black or african american, dead, 33 days	1011.4
TCGA-19-2619-01A	55 years, female, black or african american, alive, 294 days	1008.0
TCGA-14-0790-01B	64 years, female, white, dead, 419 days	954.0
TCGA-06-0157-01A	63 years, female, white, dead, 97 days	899.4
TCGA-06-0158-01A	73 years, male, white, dead, 329 days	896.3
TCGA-32-1970-01A	59 years, male, white, dead, 468 days	840.2
TCGA-08-0386-01A	74 years, male, white, dead, 548 days	820.8
TCGA-27-1835-01A	53 years, female, white, dead, 648 days	801.9
TCGA-06-2567-01A	65 years, male, white, dead, 133 days	800.0
TCGA-15-1444-01A	21 years, male, white, dead, 1537 days	760.0
TCGA-19-1390-01A	63 years, female, white, dead, 772 days	744.9
TCGA-19-5960-01A	56 years, male, white, dead, 455 days	711.5
TCGA-06-5417-01A	45 years, female, white, alive, 155 days	694.5
TCGA-06-0129-01A	30 years, male, asian, dead, 1024 days	686.7
TCGA-06-5859-01A	63 years, male, white, alive, 139 days	629.3
TCGA-06-1804-01A	81 years, female, white, dead, 414 days	420.3
TCGA-26-1442-01A	43 years, male, white, alive, 953 days	374.6
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GLIOMA - Protein expressionⁱ

Pending cancer tissue analysis