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GPM6B
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:580.5 nTPM
HPA:580.5 nTPM
FANTOM5:1020.5 Scaled Tags Per Million
Pig:387.8 nTPM
Allen mouse:8.2 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 580.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 449.4
2301 Female, age 85, both hemispheres 482.5
2188 Female, age 91, both hemispheres 469.3
2090 Male, age 80, both hemispheres 466.8
1984 Male, age 76, both hemispheres 378.8
Dorsal cochlear nucleus
nTPM: 411.3
2187 Female, age 91, both hemispheres 447.8
2378 Male, age 80, both hemispheres 431.8
2802 Male, age 74, right hemisphere 402.8
2058 Male, age 76, both hemispheres 394.3
2370 Male, age 61, both hemispheres 379.5
Dorsal tegmental nucleus
nTPM: 380.4
2083 Male, age 80, both hemispheres 457.2
2326 Male, age 74, both hemispheres 425.6
1936 Male, age 76, left hemisphere 375.0
2358 Male, age 61, both hemispheres 263.8
Dorsolateral tegmental area
nTPM: 411.6
2751 Female, age 85, both hemispheres 548.7
2654 Male, age 80, both hemispheres 454.1
2360 Male, age 74, both hemispheres 398.9
2337 Male, age 61, both hemispheres 352.2
2141 Male, age 76, both hemispheres 304.0
Kolliker-Fuse nucleus
nTPM: 432.0
2315 Male, age 76, right hemisphere 522.3
2793 Female, age 91, left hemisphere 410.3
2163 Male, age 80, both hemispheres 363.5
Lateral lemniscal nuclei
nTPM: 372.8
2036 Male, age 80, both hemispheres 401.0
2320 Female, age 91, left hemisphere 394.9
2746 Female, age 85, left hemisphere 372.1
2169 Male, age 76, both hemispheres 348.1
2453 Male, age 74, right hemisphere 348.0
Lateral parabrachial nucleus
nTPM: 436.6
2792 Male, age 76, both hemispheres 576.7
2013 Male, age 80, both hemispheres 436.3
2139 Female, age 85, right hemisphere 388.0
2790 Male, age 61, both hemispheres 345.6
Lateral vestibular nucleus
nTPM: 384.8
2311 Male, age 80, both hemispheres 420.3
2184 Male, age 76, both hemispheres 349.3
Locus coeruleus
nTPM: 310.7
2317 Female, age 72, unknown 330.8
2123 Female, age 91, both hemispheres 326.3
2788 Male, age 74, unknown 323.3
2162 Male, age 80, both hemispheres 313.0
2014 Male, age 55, unknown 304.1
2720 Male, age 74, both hemispheres 297.5
1980 Male, age 76, both hemispheres 279.8
Medial olivary nucleus
nTPM: 580.5
1943 Male, age 61, both hemispheres 669.8
1962 Male, age 76, both hemispheres 633.3
2138 Female, age 91, both hemispheres 580.9
2851 Male, age 80, both hemispheres 437.8
Medial parabrachial nucleus
nTPM: 412.6
2463 Female, age 85, right hemisphere 502.6
2170 Female, age 91, both hemispheres 484.7
2854 Male, age 80, both hemispheres 379.9
2786 Male, age 76, both hemispheres 361.3
2156 Male, age 61, both hemispheres 334.6
Medial periolivary nuclei
nTPM: 399.8
2791 Male, age 74, right hemisphere 480.3
2081 Male, age 80, both hemispheres 439.4
2458 Female, age 91, both hemispheres 395.5
2063 Male, age 76, both hemispheres 380.0
2171 Female, age 85, both hemispheres 303.7
Motor facial nucleus
nTPM: 388.1
2126 Male, age 61, both hemispheres 459.2
2365 Male, age 74, right hemisphere 438.6
2795 Female, age 91, both hemispheres 381.5
2697 Female, age 85, both hemispheres 362.3
2062 Male, age 76, both hemispheres 356.4
2327 Male, age 80, both hemispheres 330.7
Motor trigeminal nucleus
nTPM: 363.9
2321 Female, age 91, both hemispheres 393.3
2560 Male, age 74, both hemispheres 386.2
2309 Male, age 76, both hemispheres 366.3
2079 Male, age 80, both hemispheres 355.7
2335 Male, age 61, both hemispheres 318.1
Nuclei of the trapezoid body
nTPM: 372.0
2368 Female, age 91, both hemispheres 422.7
2166 Male, age 80, both hemispheres 402.1
1983 Male, age 76, both hemispheres 371.3
2159 Male, age 61, both hemispheres 357.0
2735 Female, age 85, both hemispheres 307.0
Paramedian reticular nucleus
nTPM: 414.4
2052 Male, age 76, both hemispheres 466.4
2057 Male, age 80, both hemispheres 463.0
2050 Female, age 85, both hemispheres 378.1
2313 Male, age 61, both hemispheres 350.3
Pontine nuclei
nTPM: 398.3
2454 Male, age 74, left hemisphere 499.9
2319 Female, age 91, both hemispheres 431.3
2109 Female, age 72, unknown 426.7
1863 Male, age 55, unknown 387.8
1968 Male, age 76, left hemisphere 385.3
2115 Male, age 80, left hemisphere 385.2
2727 Male, age 61, right hemisphere 361.4
2787 Female, age 85, both hemispheres 308.7
Pontine raphe nucleus
nTPM: 334.5
2122 Female, age 85, midline 338.7
2853 Male, age 76, midline 330.3
Posteroventral cochlear nucleus
nTPM: 450.0
2341 Male, age 80, both hemispheres 523.0
2135 Female, age 91, both hemispheres 521.1
2070 Male, age 76, both hemispheres 431.9
2371 Male, age 61, both hemispheres 410.8
2752 Female, age 85, both hemispheres 363.4
Principal sensory trigeminal nucleus
nTPM: 356.2
2367 Female, age 91, left hemisphere 419.8
2008 Male, age 80, left hemisphere 349.9
2324 Male, age 76, both hemispheres 345.3
2158 Male, age 61, both hemispheres 309.8
Reticular pontine nucleus, caudal
nTPM: 414.5
2457 Female, age 91, both hemispheres 452.2
2092 Male, age 76, both hemispheres 439.7
2559 Male, age 74, both hemispheres 439.3
2332 Male, age 80, right hemisphere 326.7
Reticular pontine nucleus, oral
nTPM: 438.8
2361 Male, age 74, both hemispheres 505.2
1939 Male, age 80, both hemispheres 455.0
2366 Female, age 91, both hemispheres 424.1
2012 Female, age 85, both hemispheres 416.6
2167 Male, age 76, both hemispheres 392.9
Reticulotegmental nucleus
nTPM: 362.0
2322 Female, age 91, both hemispheres 420.4
2333 Male, age 80, both hemispheres 381.2
2452 Male, age 74, both hemispheres 353.6
2325 Male, age 76, both hemispheres 292.9
Spinal trigeminal nucleus, oral
nTPM: 370.0
1978 Male, age 76, both hemispheres 390.7
2164 Male, age 80, both hemispheres 368.4
2737 Female, age 85, both hemispheres 350.7
Subcoeruleus area
nTPM: 396.3
2369 Female, age 85, left hemisphere 597.8
1958 Male, age 80, both hemispheres 379.3
2089 Male, age 76, left hemisphere 363.5
2451 Male, age 74, both hemispheres 335.6
2323 Female, age 91, left hemisphere 305.3
Superior olive
nTPM: 405.7
2364 Male, age 74, right hemisphere 484.8
2020 Male, age 76, both hemispheres 456.0
2329 Male, age 80, right hemisphere 375.0
1875 Female, age 85, both hemispheres 357.8
2561 Female, age 91, both hemispheres 354.8
Superior vestibular nucleus
nTPM: 445.6
2383 Male, age 74, both hemispheres 469.7
2015 Male, age 80, both hemispheres 434.5
2061 Male, age 76, both hemispheres 432.7
Ventral periolivary nuclei
nTPM: 368.9
2023 Male, age 76, both hemispheres 504.1
2165 Male, age 80, both hemispheres 365.3
2794 Female, age 91, left hemisphere 313.8
2130 Female, age 85, both hemispheres 292.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 393.8
2456 Female, age 91, both hemispheres 445.9
1959 Male, age 76, both hemispheres 401.0
2449 Male, age 74, both hemispheres 386.0
2161 Male, age 80, both hemispheres 380.0
2359 Male, age 61, both hemispheres 376.1
2840 Female, age 85, both hemispheres 373.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1020.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1020.5
FF:10182-103D2 60 years, female 1040.4
FF:10165-103B3 76 years, female 1000.5
Pons
Scaled Tags Per Million: 778.7
FF:10033-101E6 18-54 years, mixed 778.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 387.8
Pig sample Sample description nTPM
Pons
nTPM: 387.9
Samples: 4

Max nTPM: 491.1
Min nTPM: 312.5
Sample A Female 346.1
Sample B Female 312.5
Sample C Male 401.7
Sample D Male 491.1

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.2
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 8.2
544520 Antisense, RP_040324_01_G06, Mouse strain C57BL/6J (56 days, male) 8.5
74357593 Antisense, RP_060117_01_A08, Mouse strain C57BL/6J (56 days, male) 7.9

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.