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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:110.0 nTPM
HPA:110.0 nTPM
GTEx:122.3 nTPM
FANTOM5:105.3 Scaled Tags Per Million
Pig:84.8 nTPM
Mouse:97.2 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 110.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 95.3
2411 Female, age 72, unknown 112.2
2219 Male, age 76, both hemispheres 101.9
1870 Female, age 42, unknown 99.9
1827 Male, age 72, unknown 98.2
1833 Male, age 53, unknown 96.5
2666 Male, age 74, left hemisphere 95.8
1830 Male, age 51, unknown 91.9
2828 Female, age 72, unknown 88.0
2019 Male, age 18, unknown 84.4
2586 Male, age 75, left hemisphere 84.1
Dorsal raphe nucleus
nTPM: 104.0
2298 Female, age 72, unknown 115.0
2047 Male, age 72, unknown 111.0
2750 Male, age 76, both hemispheres 104.8
1828 Male, age 53, unknown 98.0
2016 Female, age 72, unknown 91.3
Inferior colliculus
nTPM: 88.9
2849 Male, age 72, unknown 90.4
1848 Female, age 42, unknown 90.2
2097 Female, age 72, unknown 90.2
1890 Male, age 53, unknown 84.8
Median raphe nucleus
nTPM: 110.0
2220 Male, age 76, midline 110.0
Pedunculopontine tegmental nucleus
nTPM: 103.3
2334 Male, age 80, both hemispheres 111.6
1921 Female, age 85, both hemispheres 107.0
2338 Male, age 61, both hemispheres 91.2
Periaquaductal grey, anterior
nTPM: 92.3
1947 Male, age 18, unknown 96.8
1795 Male, age 51, unknown 93.8
2502 Female, age 75, unknown 86.4
Periaquaductal grey, dorsal
nTPM: 92.7
1840 Male, age 53, unknown 101.5
2464 Female, age 72, unknown 92.9
2850 Male, age 76, both hemispheres 91.4
1831 Male, age 72, unknown 85.0
Periaquaductal grey, lateral
nTPM: 88.7
2053 Male, age 18, unknown 90.9
2272 Male, age 74, both hemispheres 89.6
2140 Male, age 76, both hemispheres 85.6
Pretectal area
nTPM: 91.6
2224 Female, age 72, unknown 104.0
2825 Male, age 18, unknown 96.1
1816 Male, age 51, unknown 92.6
2273 Male, age 74, both hemispheres 91.6
2667 Female, age 75, unknown 91.6
1944 Female, age 72, unknown 91.4
1817 Female, age 42, unknown 90.9
2007 Male, age 72, unknown 90.5
1815 Male, age 53, unknown 89.7
2316 Male, age 76, right hemisphere 84.6
2407 Male, age 75, both hemispheres 84.2
Red nucleus
nTPM: 84.8
1821 Female, age 72, unknown 92.6
2725 Female, age 75, unknown 91.3
2584 Male, age 75, left hemisphere 88.0
2588 Male, age 74, left hemisphere 85.7
1954 Female, age 42, unknown 84.3
2769 Male, age 72, unknown 83.9
2227 Male, age 72, unknown 83.7
2503 Female, age 72, unknown 83.5
1904 Male, age 53, unknown 81.7
2785 Male, age 18, unknown 81.6
1865 Male, age 51, unknown 81.0
2823 Male, age 76, right hemisphere 80.4
Substantia nigra
nTPM: 105.0
1916 Female, age 42, unknown 127.1
2241 Male, age 72, unknown 122.5
1851 Male, age 51, unknown 111.8
1941 Male, age 53, unknown 107.7
2699 Male, age 18, unknown 106.5
2409 Female, age 72, unknown 103.5
1889 Female, age 72, unknown 98.6
2665 Male, age 74, both hemispheres 91.8
2590 Female, age 75, unknown 90.1
2583 Male, age 75, right hemisphere 89.8
Superior colliculus
nTPM: 89.8
2668 Female, age 75, unknown 100.5
1796 Male, age 53, unknown 94.5
1839 Male, age 51, unknown 93.3
1895 Male, age 76, right hemisphere 92.7
2261 Male, age 18, unknown 90.3
2587 Male, age 74, left hemisphere 89.7
2087 Female, age 72, unknown 88.2
1913 Female, age 42, unknown 85.7
2664 Male, age 75, both hemispheres 83.8
1995 Male, age 72, unknown 79.3
Ventral tegmental area
nTPM: 103.6
1915 Female, age 42, unknown 112.3
2410 Female, age 72, unknown 109.7
2218 Male, age 76, both hemispheres 104.2
2223 Female, age 72, unknown 100.1
2021 Male, age 53, unknown 98.5
1942 Male, age 51, unknown 96.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 122.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 122.3
Samples: 139

Max nTPM: 276.7
Min nTPM: 56.1
Std nTPM: 46.6
Median nTPM: 113.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 276.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 269.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 258.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 255.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 235.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 231.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 220.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 212.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 209.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 207.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 199.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 196.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 193.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 188.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 185.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 184.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 180.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 179.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 178.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 173.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 172.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 171.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 170.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 167.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 162.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 158.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 157.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 157.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 149.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 146.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 145.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 144.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 143.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 141.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 139.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 138.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 137.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 137.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 137.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 136.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 136.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 136.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 134.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 134.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 134.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 132.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 132.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 131.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 129.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 126.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 126.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 125.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 124.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 124.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 124.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 124.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 123.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 123.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 123.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 120.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 120.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 120.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 119.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 118.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 118.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 117.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 115.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 114.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 114.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 113.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 112.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 112.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 110.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 110.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 109.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 107.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 107.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 107.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 106.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 105.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 105.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 104.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 104.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 102.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 99.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 98.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 98.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 97.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 97.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 97.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 95.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 95.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 95.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 94.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 94.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 93.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 92.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 91.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 89.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 89.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 87.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 87.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 86.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 85.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 85.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 83.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 83.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 82.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 82.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 81.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 81.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 80.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 80.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 79.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 78.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 77.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 77.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 77.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 75.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 74.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 74.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 73.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 73.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 72.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 71.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 70.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 67.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 67.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 67.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 64.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 62.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 60.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 56.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 105.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 105.3
FF:10158-103A5 76 years, female 105.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.8
Pig sample Sample description nTPM
Midbrain
nTPM: 74.0
Samples: 4

Max nTPM: 77.5
Min nTPM: 67.7
Sample A Female 77.5
Sample B Female 74.3
Sample C Male 76.6
Sample D Male 67.7
Periaqueductal gray
nTPM: 68.5
Samples: 3

Max nTPM: 83.3
Min nTPM: 60.1
Sample B Female 62.2
Sample C Male 83.3
Sample D Male 60.1
Substantia nigra
nTPM: 84.8
Samples: 4

Max nTPM: 128.2
Min nTPM: 45.7
Sample A Female 128.2
Sample B Female 69.0
Sample C Male 96.4
Sample D Male 45.7
Superior colliculi
nTPM: 67.7
Samples: 4

Max nTPM: 84.7
Min nTPM: 43.3
Sample A Female 84.7
Sample B Female 43.3
Sample C Male 76.9
Sample D Male 66.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 97.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 97.2
Samples: 4

Max nTPM: 102.0
Min nTPM: 90.7
Sample A Male 99.2
Sample B Male 102.0
Sample C Female 90.7
Sample D Female 96.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
71232582 Antisense, RP_050412_01_E11, Mouse strain C57BL/6J (56 days, male) 1.7

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