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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:268.7 nTPM
HPA:268.7 nTPM
GTEx:159.6 nTPM
FANTOM5:401.0 Scaled Tags Per Million
Pig:97.4 nTPM
Mouse:20.3 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 268.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 215.3
2586 Male, age 75, left hemisphere 304.5
2666 Male, age 74, left hemisphere 304.0
1833 Male, age 53, unknown 247.8
1830 Male, age 51, unknown 239.6
2828 Female, age 72, unknown 232.9
1870 Female, age 42, unknown 185.4
2219 Male, age 76, both hemispheres 182.1
2411 Female, age 72, unknown 156.1
1827 Male, age 72, unknown 152.3
2019 Male, age 18, unknown 148.0
Dorsal raphe nucleus
nTPM: 139.7
2016 Female, age 72, unknown 194.5
2750 Male, age 76, both hemispheres 175.0
1828 Male, age 53, unknown 146.3
2047 Male, age 72, unknown 113.6
2298 Female, age 72, unknown 69.3
Inferior colliculus
nTPM: 142.4
2849 Male, age 72, unknown 214.8
1848 Female, age 42, unknown 148.9
1890 Male, age 53, unknown 135.3
2097 Female, age 72, unknown 70.7
Median raphe nucleus
nTPM: 115.0
2220 Male, age 76, midline 115.0
Pedunculopontine tegmental nucleus
nTPM: 152.6
2334 Male, age 80, both hemispheres 176.1
2338 Male, age 61, both hemispheres 163.1
1921 Female, age 85, both hemispheres 118.6
Periaquaductal grey, anterior
nTPM: 139.2
2502 Female, age 75, unknown 152.6
1947 Male, age 18, unknown 135.1
1795 Male, age 51, unknown 129.8
Periaquaductal grey, dorsal
nTPM: 147.4
1831 Male, age 72, unknown 156.5
2464 Female, age 72, unknown 156.4
2850 Male, age 76, both hemispheres 156.4
1840 Male, age 53, unknown 120.3
Periaquaductal grey, lateral
nTPM: 143.1
2053 Male, age 18, unknown 173.6
2140 Male, age 76, both hemispheres 135.5
2272 Male, age 74, both hemispheres 120.1
Pretectal area
nTPM: 142.3
2407 Male, age 75, both hemispheres 205.5
1815 Male, age 53, unknown 195.2
2316 Male, age 76, right hemisphere 187.3
2825 Male, age 18, unknown 181.3
1817 Female, age 42, unknown 151.3
2007 Male, age 72, unknown 118.1
2667 Female, age 75, unknown 116.4
1944 Female, age 72, unknown 113.9
2224 Female, age 72, unknown 109.2
1816 Male, age 51, unknown 98.9
2273 Male, age 74, both hemispheres 88.6
Red nucleus
nTPM: 268.7
2588 Male, age 74, left hemisphere 337.4
2503 Female, age 72, unknown 325.9
1904 Male, age 53, unknown 313.6
2823 Male, age 76, right hemisphere 301.7
1865 Male, age 51, unknown 291.9
2769 Male, age 72, unknown 272.0
2227 Male, age 72, unknown 267.9
2584 Male, age 75, left hemisphere 236.9
1954 Female, age 42, unknown 228.2
2785 Male, age 18, unknown 218.8
2725 Female, age 75, unknown 217.2
1821 Female, age 72, unknown 213.2
Substantia nigra
nTPM: 184.4
2699 Male, age 18, unknown 285.4
2665 Male, age 74, both hemispheres 245.1
2590 Female, age 75, unknown 231.5
2583 Male, age 75, right hemisphere 216.1
2409 Female, age 72, unknown 190.6
1851 Male, age 51, unknown 180.2
1889 Female, age 72, unknown 139.3
2241 Male, age 72, unknown 124.3
1916 Female, age 42, unknown 118.6
1941 Male, age 53, unknown 113.0
Superior colliculus
nTPM: 194.7
1995 Male, age 72, unknown 277.2
2664 Male, age 75, both hemispheres 229.7
1913 Female, age 42, unknown 227.5
2587 Male, age 74, left hemisphere 221.9
1839 Male, age 51, unknown 207.4
2668 Female, age 75, unknown 190.6
1895 Male, age 76, right hemisphere 185.4
1796 Male, age 53, unknown 154.1
2261 Male, age 18, unknown 127.7
2087 Female, age 72, unknown 125.6
Ventral tegmental area
nTPM: 154.3
2410 Female, age 72, unknown 180.8
2021 Male, age 53, unknown 159.4
1942 Male, age 51, unknown 157.1
2223 Female, age 72, unknown 148.8
1915 Female, age 42, unknown 147.9
2218 Male, age 76, both hemispheres 131.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 159.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 159.6
Samples: 139

Max nTPM: 442.7
Min nTPM: 29.0
Std nTPM: 89.2
Median nTPM: 135.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 442.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 422.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 407.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 383.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 372.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 365.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 362.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 358.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 328.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 301.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 300.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 299.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 294.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 287.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 282.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 273.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 270.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 262.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 261.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 254.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 253.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 252.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 248.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 241.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 241.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 240.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 239.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 238.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 236.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 234.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 231.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 229.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 221.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 218.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 218.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 217.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 211.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 206.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 200.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 194.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 194.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 194.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 185.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 180.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 177.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 174.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 174.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 171.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 170.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 168.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 167.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 166.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 161.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 159.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 158.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 158.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 157.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 156.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 153.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 153.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 147.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 146.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 144.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 143.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 142.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 141.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 139.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 136.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 135.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 135.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 132.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 131.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 131.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 129.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 128.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 125.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 123.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 123.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 122.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 122.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 122.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 119.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 119.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 118.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 118.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 117.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 116.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 115.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 111.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 111.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 109.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 109.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 109.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 107.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 104.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 101.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 101.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 98.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 95.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 94.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 92.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 86.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 85.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 85.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 85.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 83.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 82.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 82.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 80.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 80.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 79.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 79.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 78.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 77.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 76.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 76.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 75.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 73.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 70.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 70.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 67.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 65.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 63.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 62.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 60.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 59.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 59.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 58.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 57.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 51.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 46.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 44.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 39.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 32.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 29.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 401.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 401.0
FF:10158-103A5 76 years, female 401.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 97.4
Pig sample Sample description nTPM
Midbrain
nTPM: 84.4
Samples: 4

Max nTPM: 111.5
Min nTPM: 61.7
Sample A Female 87.4
Sample B Female 111.5
Sample C Male 61.7
Sample D Male 77.1
Periaqueductal gray
nTPM: 82.2
Samples: 3

Max nTPM: 94.9
Min nTPM: 70.9
Sample B Female 94.9
Sample C Male 70.9
Sample D Male 80.9
Substantia nigra
nTPM: 97.4
Samples: 4

Max nTPM: 145.5
Min nTPM: 72.3
Sample A Female 77.6
Sample B Female 72.3
Sample C Male 94.2
Sample D Male 145.5
Superior colliculi
nTPM: 76.2
Samples: 4

Max nTPM: 104.3
Min nTPM: 51.9
Sample A Female 74.6
Sample B Female 51.9
Sample C Male 73.9
Sample D Male 104.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 20.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 20.3
Samples: 4

Max nTPM: 22.6
Min nTPM: 16.8
Sample A Male 16.8
Sample B Male 21.6
Sample C Female 20.1
Sample D Female 22.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
68196925 Antisense, RP_041116_01_F03, Mouse strain C57BL/6J (56 days, male) 0.6

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