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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:47.5 nTPM
HPA:47.5 nTPM
GTEx:44.1 nTPM
FANTOM5:31.5 Scaled Tags Per Million
Pig:72.3 nTPM
Mouse:66.9 nTPM
Allen mouse:8.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 47.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 44.5
2019 Male, age 18, unknown 46.0
2411 Female, age 72, unknown 45.7
1870 Female, age 42, unknown 45.0
1827 Male, age 72, unknown 44.5
1830 Male, age 51, unknown 44.2
1833 Male, age 53, unknown 44.2
2666 Male, age 74, left hemisphere 44.2
2219 Male, age 76, both hemispheres 44.1
2828 Female, age 72, unknown 43.9
2586 Male, age 75, left hemisphere 42.8
Dorsal raphe nucleus
nTPM: 45.9
2298 Female, age 72, unknown 47.3
2047 Male, age 72, unknown 46.5
2750 Male, age 76, both hemispheres 45.8
1828 Male, age 53, unknown 45.2
2016 Female, age 72, unknown 44.5
Inferior colliculus
nTPM: 45.5
2097 Female, age 72, unknown 46.0
2849 Male, age 72, unknown 45.4
1848 Female, age 42, unknown 45.3
1890 Male, age 53, unknown 45.2
Median raphe nucleus
nTPM: 45.7
2220 Male, age 76, midline 45.7
Pedunculopontine tegmental nucleus
nTPM: 46.9
2338 Male, age 61, both hemispheres 48.4
2334 Male, age 80, both hemispheres 46.8
1921 Female, age 85, both hemispheres 45.5
Periaquaductal grey, anterior
nTPM: 44.4
1795 Male, age 51, unknown 45.0
1947 Male, age 18, unknown 44.7
2502 Female, age 75, unknown 43.4
Periaquaductal grey, dorsal
nTPM: 44.7
2850 Male, age 76, both hemispheres 46.5
1840 Male, age 53, unknown 46.0
1831 Male, age 72, unknown 43.7
2464 Female, age 72, unknown 42.8
Periaquaductal grey, lateral
nTPM: 44.4
2272 Male, age 74, both hemispheres 45.8
2053 Male, age 18, unknown 43.7
2140 Male, age 76, both hemispheres 43.6
Pretectal area
nTPM: 46.1
1817 Female, age 42, unknown 49.4
1944 Female, age 72, unknown 48.3
2667 Female, age 75, unknown 47.0
1815 Male, age 53, unknown 46.7
1816 Male, age 51, unknown 46.5
2007 Male, age 72, unknown 46.3
2273 Male, age 74, both hemispheres 45.9
2224 Female, age 72, unknown 45.7
2407 Male, age 75, both hemispheres 44.5
2825 Male, age 18, unknown 44.3
2316 Male, age 76, right hemisphere 42.3
Red nucleus
nTPM: 45.0
1821 Female, age 72, unknown 48.2
2725 Female, age 75, unknown 46.6
2503 Female, age 72, unknown 45.6
2785 Male, age 18, unknown 45.4
1865 Male, age 51, unknown 45.1
1954 Female, age 42, unknown 45.1
2823 Male, age 76, right hemisphere 44.8
2769 Male, age 72, unknown 44.7
1904 Male, age 53, unknown 44.5
2588 Male, age 74, left hemisphere 43.8
2227 Male, age 72, unknown 43.3
2584 Male, age 75, left hemisphere 42.4
Substantia nigra
nTPM: 47.5
1916 Female, age 42, unknown 50.9
2241 Male, age 72, unknown 50.4
1851 Male, age 51, unknown 49.3
1889 Female, age 72, unknown 48.6
1941 Male, age 53, unknown 47.3
2699 Male, age 18, unknown 47.3
2665 Male, age 74, both hemispheres 46.3
2409 Female, age 72, unknown 45.7
2590 Female, age 75, unknown 45.6
2583 Male, age 75, right hemisphere 43.8
Superior colliculus
nTPM: 44.7
2587 Male, age 74, left hemisphere 46.6
1796 Male, age 53, unknown 46.2
1895 Male, age 76, right hemisphere 45.1
2668 Female, age 75, unknown 44.8
2261 Male, age 18, unknown 44.7
2087 Female, age 72, unknown 44.5
1839 Male, age 51, unknown 44.4
1995 Male, age 72, unknown 44.2
1913 Female, age 42, unknown 43.8
2664 Male, age 75, both hemispheres 43.3
Ventral tegmental area
nTPM: 46.2
2410 Female, age 72, unknown 50.5
2218 Male, age 76, both hemispheres 47.9
1915 Female, age 42, unknown 46.6
2021 Male, age 53, unknown 44.4
2223 Female, age 72, unknown 44.0
1942 Male, age 51, unknown 43.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 44.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 44.1
Samples: 139

Max nTPM: 68.9
Min nTPM: 32.7
Std nTPM: 7.3
Median nTPM: 42.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 68.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 67.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 67.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 66.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 66.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 59.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 59.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 56.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 55.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 55.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 54.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 54.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 53.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 52.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 52.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 52.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 52.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 51.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 50.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 50.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 50.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 50.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 50.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 49.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 49.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 49.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 49.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 49.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 48.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 48.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 48.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 48.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 48.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 47.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 47.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 47.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 47.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 47.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 47.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 47.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 46.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 46.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 46.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 46.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 46.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 45.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 45.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 45.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 45.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 44.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 44.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 44.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 44.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 44.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 44.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 43.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 43.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 43.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 42.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 42.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 42.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 42.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 42.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 42.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 42.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 41.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 41.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 41.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 41.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 41.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 41.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 41.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 41.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 41.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 41.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 40.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 40.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 40.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 40.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 40.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 40.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 40.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 40.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 40.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 40.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 39.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 39.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 39.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 39.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 39.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 39.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 39.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 39.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 38.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 38.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 38.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 38.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 38.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 37.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 37.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 37.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 37.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 36.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 36.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 36.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 36.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 36.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 35.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 35.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 35.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 35.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 35.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 35.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 34.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 34.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 33.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 33.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 33.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 31.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.5
FF:10158-103A5 76 years, female 31.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.3
Pig sample Sample description nTPM
Midbrain
nTPM: 65.0
Samples: 4

Max nTPM: 84.8
Min nTPM: 55.0
Sample A Female 84.8
Sample B Female 57.3
Sample C Male 62.9
Sample D Male 55.0
Periaqueductal gray
nTPM: 50.7
Samples: 3

Max nTPM: 54.3
Min nTPM: 44.9
Sample B Female 53.0
Sample C Male 54.3
Sample D Male 44.9
Substantia nigra
nTPM: 63.2
Samples: 4

Max nTPM: 74.5
Min nTPM: 57.1
Sample A Female 74.5
Sample B Female 62.3
Sample C Male 58.9
Sample D Male 57.1
Superior colliculi
nTPM: 72.3
Samples: 4

Max nTPM: 83.2
Min nTPM: 68.1
Sample A Female 83.2
Sample B Female 68.1
Sample C Male 69.3
Sample D Male 68.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 66.9
Samples: 4

Max nTPM: 68.1
Min nTPM: 65.5
Sample A Male 66.8
Sample B Male 68.1
Sample C Female 65.5
Sample D Female 67.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.4
68546272 Antisense, RP_050120_02_C07, Mouse strain C57BL/6J (56 days, male) 11.7
68499524 Antisense, RP_050118_01_G04, Mouse strain C57BL/6J (56 days, male) 5.0

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