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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:670.8 nTPM
HPA:670.8 nTPM
GTEx:719.5 nTPM
FANTOM5:1561.9 Scaled Tags Per Million
Pig:113.6 nTPM
Mouse:115.4 nTPM
Allen mouse:1.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 670.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 564.8
2411 Female, age 72, unknown 694.1
1830 Male, age 51, unknown 674.0
1870 Female, age 42, unknown 656.4
1833 Male, age 53, unknown 622.1
2019 Male, age 18, unknown 593.6
2828 Female, age 72, unknown 538.9
1827 Male, age 72, unknown 487.3
2666 Male, age 74, left hemisphere 486.7
2219 Male, age 76, both hemispheres 454.0
2586 Male, age 75, left hemisphere 441.4
Dorsal raphe nucleus
nTPM: 500.9
2750 Male, age 76, both hemispheres 711.3
2016 Female, age 72, unknown 492.4
1828 Male, age 53, unknown 473.5
2298 Female, age 72, unknown 419.6
2047 Male, age 72, unknown 407.6
Inferior colliculus
nTPM: 460.7
1848 Female, age 42, unknown 479.4
1890 Male, age 53, unknown 461.2
2849 Male, age 72, unknown 452.9
2097 Female, age 72, unknown 449.2
Median raphe nucleus
nTPM: 477.7
2220 Male, age 76, midline 477.7
Pedunculopontine tegmental nucleus
nTPM: 543.8
2334 Male, age 80, both hemispheres 581.5
2338 Male, age 61, both hemispheres 536.9
1921 Female, age 85, both hemispheres 512.9
Periaquaductal grey, anterior
nTPM: 446.1
1947 Male, age 18, unknown 473.5
2502 Female, age 75, unknown 468.1
1795 Male, age 51, unknown 396.6
Periaquaductal grey, dorsal
nTPM: 419.0
2464 Female, age 72, unknown 488.5
1831 Male, age 72, unknown 435.8
1840 Male, age 53, unknown 378.4
2850 Male, age 76, both hemispheres 373.5
Periaquaductal grey, lateral
nTPM: 423.4
2053 Male, age 18, unknown 450.8
2272 Male, age 74, both hemispheres 449.3
2140 Male, age 76, both hemispheres 370.0
Pretectal area
nTPM: 456.7
2316 Male, age 76, right hemisphere 545.1
1815 Male, age 53, unknown 529.5
2825 Male, age 18, unknown 477.8
1817 Female, age 42, unknown 475.1
2407 Male, age 75, both hemispheres 463.4
2273 Male, age 74, both hemispheres 459.1
2007 Male, age 72, unknown 458.4
2224 Female, age 72, unknown 435.7
2667 Female, age 75, unknown 413.9
1944 Female, age 72, unknown 388.2
1816 Male, age 51, unknown 377.2
Red nucleus
nTPM: 670.8
1865 Male, age 51, unknown 806.7
1821 Female, age 72, unknown 805.2
1904 Male, age 53, unknown 756.1
2823 Male, age 76, right hemisphere 709.4
1954 Female, age 42, unknown 679.9
2769 Male, age 72, unknown 679.6
2227 Male, age 72, unknown 674.7
2503 Female, age 72, unknown 667.3
2785 Male, age 18, unknown 616.9
2588 Male, age 74, left hemisphere 579.7
2725 Female, age 75, unknown 576.7
2584 Male, age 75, left hemisphere 497.9
Substantia nigra
nTPM: 497.7
1851 Male, age 51, unknown 568.3
2409 Female, age 72, unknown 543.2
2590 Female, age 75, unknown 540.4
1889 Female, age 72, unknown 526.9
2241 Male, age 72, unknown 500.3
2699 Male, age 18, unknown 494.9
2583 Male, age 75, right hemisphere 485.8
1916 Female, age 42, unknown 448.7
1941 Male, age 53, unknown 441.1
2665 Male, age 74, both hemispheres 427.0
Superior colliculus
nTPM: 516.4
1913 Female, age 42, unknown 657.4
1995 Male, age 72, unknown 607.7
1895 Male, age 76, right hemisphere 606.6
2587 Male, age 74, left hemisphere 561.1
2668 Female, age 75, unknown 528.5
1839 Male, age 51, unknown 521.4
1796 Male, age 53, unknown 457.6
2087 Female, age 72, unknown 412.9
2664 Male, age 75, both hemispheres 410.1
2261 Male, age 18, unknown 400.9
Ventral tegmental area
nTPM: 540.3
2223 Female, age 72, unknown 654.9
2410 Female, age 72, unknown 618.6
2021 Male, age 53, unknown 519.9
1915 Female, age 42, unknown 494.7
1942 Male, age 51, unknown 482.6
2218 Male, age 76, both hemispheres 470.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 719.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 719.5
Samples: 139

Max nTPM: 2326.5
Min nTPM: 246.7
Std nTPM: 390.8
Median nTPM: 598.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2326.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1915.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1878.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1767.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1672.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1654.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1594.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1478.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1421.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1399.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1364.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1363.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1303.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1289.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1281.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1258.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1219.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1191.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1181.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1178.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1147.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1145.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1098.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1063.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1032.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1030.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1021.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1019.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 981.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 957.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 947.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 946.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 945.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 909.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 908.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 881.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 865.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 853.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 826.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 824.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 813.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 789.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 786.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 776.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 770.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 770.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 768.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 759.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 742.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 741.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 735.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 726.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 711.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 669.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 664.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 658.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 648.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 646.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 633.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 633.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 632.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 628.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 622.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 622.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 620.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 620.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 614.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 605.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 603.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 598.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 598.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 596.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 588.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 586.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 584.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 573.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 562.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 561.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 559.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 555.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 552.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 540.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 536.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 532.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 530.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 527.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 525.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 524.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 522.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 518.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 498.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 497.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 491.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 491.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 487.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 486.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 476.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 476.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 462.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 459.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 456.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 449.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 446.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 440.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 438.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 437.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 436.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 430.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 422.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 409.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 405.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 403.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 402.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 398.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 394.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 393.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 389.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 389.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 388.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 386.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 380.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 376.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 373.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 360.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 353.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 338.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 337.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 323.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 309.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 309.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 308.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 307.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 301.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 298.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 289.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 279.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 272.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 252.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 246.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1561.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1561.9
FF:10158-103A5 76 years, female 1561.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 113.6
Pig sample Sample description nTPM
Midbrain
nTPM: 113.6
Samples: 4

Max nTPM: 188.2
Min nTPM: 64.1
Sample A Female 188.2
Sample B Female 121.0
Sample C Male 64.1
Sample D Male 81.0
Periaqueductal gray
nTPM: 83.6
Samples: 3

Max nTPM: 97.4
Min nTPM: 66.1
Sample B Female 97.4
Sample C Male 66.1
Sample D Male 87.2
Substantia nigra
nTPM: 110.4
Samples: 4

Max nTPM: 134.1
Min nTPM: 85.0
Sample A Female 134.1
Sample B Female 90.9
Sample C Male 85.0
Sample D Male 131.6
Superior colliculi
nTPM: 101.2
Samples: 4

Max nTPM: 128.5
Min nTPM: 76.1
Sample A Female 128.5
Sample B Female 76.1
Sample C Male 90.7
Sample D Male 109.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 115.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.4
Samples: 4

Max nTPM: 120.8
Min nTPM: 111.3
Sample A Male 115.9
Sample B Male 113.4
Sample C Female 111.3
Sample D Female 120.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.8
71656904 Antisense, RP_050927_04_E05, Mouse strain C57BL/6J (56 days, male) 1.8

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