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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:145.3 nTPM
HPA:145.3 nTPM
GTEx:122.0 nTPM
FANTOM5:163.1 Scaled Tags Per Million
Pig:162.0 nTPM
Mouse:398.9 nTPM
Allen mouse:12.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 145.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 137.6
2828 Female, age 72, unknown 159.3
2586 Male, age 75, left hemisphere 157.0
2019 Male, age 18, unknown 143.0
2411 Female, age 72, unknown 141.2
1827 Male, age 72, unknown 138.2
2666 Male, age 74, left hemisphere 137.8
1870 Female, age 42, unknown 129.8
1833 Male, age 53, unknown 125.5
2219 Male, age 76, both hemispheres 124.3
1830 Male, age 51, unknown 119.7
Dorsal raphe nucleus
nTPM: 134.4
2298 Female, age 72, unknown 142.7
1828 Male, age 53, unknown 141.2
2047 Male, age 72, unknown 132.0
2750 Male, age 76, both hemispheres 130.2
2016 Female, age 72, unknown 125.7
Inferior colliculus
nTPM: 132.7
2097 Female, age 72, unknown 138.8
1890 Male, age 53, unknown 135.8
1848 Female, age 42, unknown 134.2
2849 Male, age 72, unknown 122.0
Median raphe nucleus
nTPM: 125.9
2220 Male, age 76, midline 125.9
Pedunculopontine tegmental nucleus
nTPM: 127.1
1921 Female, age 85, both hemispheres 133.4
2334 Male, age 80, both hemispheres 130.1
2338 Male, age 61, both hemispheres 118.0
Periaquaductal grey, anterior
nTPM: 141.2
1795 Male, age 51, unknown 146.1
2502 Female, age 75, unknown 140.4
1947 Male, age 18, unknown 137.1
Periaquaductal grey, dorsal
nTPM: 128.1
2850 Male, age 76, both hemispheres 129.8
2464 Female, age 72, unknown 128.0
1831 Male, age 72, unknown 127.9
1840 Male, age 53, unknown 126.8
Periaquaductal grey, lateral
nTPM: 123.7
2272 Male, age 74, both hemispheres 125.6
2053 Male, age 18, unknown 125.2
2140 Male, age 76, both hemispheres 120.4
Pretectal area
nTPM: 145.3
1816 Male, age 51, unknown 165.6
1944 Female, age 72, unknown 161.5
1817 Female, age 42, unknown 160.7
2007 Male, age 72, unknown 160.7
2667 Female, age 75, unknown 158.8
1815 Male, age 53, unknown 149.6
2273 Male, age 74, both hemispheres 135.4
2224 Female, age 72, unknown 131.1
2407 Male, age 75, both hemispheres 128.9
2316 Male, age 76, right hemisphere 123.7
2825 Male, age 18, unknown 122.6
Red nucleus
nTPM: 129.9
2785 Male, age 18, unknown 141.8
1821 Female, age 72, unknown 139.4
2503 Female, age 72, unknown 135.5
2823 Male, age 76, right hemisphere 134.5
2725 Female, age 75, unknown 133.6
2769 Male, age 72, unknown 131.8
2227 Male, age 72, unknown 129.8
1954 Female, age 42, unknown 128.1
1865 Male, age 51, unknown 127.5
1904 Male, age 53, unknown 124.4
2588 Male, age 74, left hemisphere 117.5
2584 Male, age 75, left hemisphere 114.5
Substantia nigra
nTPM: 135.5
1916 Female, age 42, unknown 164.3
1889 Female, age 72, unknown 156.7
1851 Male, age 51, unknown 150.4
1941 Male, age 53, unknown 144.3
2699 Male, age 18, unknown 136.5
2241 Male, age 72, unknown 134.2
2409 Female, age 72, unknown 126.6
2665 Male, age 74, both hemispheres 119.4
2590 Female, age 75, unknown 114.9
2583 Male, age 75, right hemisphere 107.9
Superior colliculus
nTPM: 140.9
2087 Female, age 72, unknown 162.3
1796 Male, age 53, unknown 147.3
2668 Female, age 75, unknown 147.0
2587 Male, age 74, left hemisphere 142.6
2261 Male, age 18, unknown 142.0
2664 Male, age 75, both hemispheres 139.7
1995 Male, age 72, unknown 134.4
1913 Female, age 42, unknown 133.5
1895 Male, age 76, right hemisphere 130.0
1839 Male, age 51, unknown 129.9
Ventral tegmental area
nTPM: 137.1
1915 Female, age 42, unknown 148.0
2410 Female, age 72, unknown 145.1
2218 Male, age 76, both hemispheres 142.0
2223 Female, age 72, unknown 132.8
1942 Male, age 51, unknown 130.7
2021 Male, age 53, unknown 123.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 122.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 122.0
Samples: 139

Max nTPM: 266.3
Min nTPM: 40.0
Std nTPM: 35.7
Median nTPM: 120.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 266.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 238.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 216.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 202.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 198.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 196.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 192.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 191.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 189.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 176.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 174.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 168.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 167.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 167.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 165.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 164.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 163.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 160.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 160.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 159.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 154.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 152.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 152.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 150.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 149.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 148.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 148.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 148.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 145.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 144.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 142.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 141.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 138.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 136.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 136.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 135.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 133.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 133.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 133.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 133.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 133.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 133.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 132.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 132.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 131.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 131.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 131.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 130.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 130.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 130.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 129.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 129.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 128.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 127.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 127.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 126.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 125.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 125.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 125.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 124.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 124.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 124.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 123.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 123.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 121.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 121.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 121.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 120.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 120.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 120.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 119.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 119.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 118.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 117.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 116.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 115.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 114.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 113.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 113.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 113.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 111.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 111.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 111.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 110.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 110.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 110.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 109.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 108.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 107.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 106.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 105.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 105.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 104.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 104.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 103.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 102.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 101.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 101.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 101.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 100.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 100.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 100.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 99.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 99.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 97.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 97.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 97.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 97.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 96.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 95.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 94.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 93.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 92.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 92.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 91.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 91.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 91.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 91.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 89.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 86.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 86.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 83.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 82.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 80.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 80.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 79.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 78.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 77.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 74.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 73.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 72.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 72.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 71.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 68.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 67.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 62.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 48.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 40.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 163.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 163.1
FF:10158-103A5 76 years, female 163.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 162.0
Pig sample Sample description nTPM
Midbrain
nTPM: 142.5
Samples: 4

Max nTPM: 186.9
Min nTPM: 126.1
Sample A Female 126.1
Sample B Female 129.5
Sample C Male 186.9
Sample D Male 127.3
Periaqueductal gray
nTPM: 101.1
Samples: 3

Max nTPM: 120.3
Min nTPM: 80.0
Sample B Female 120.3
Sample C Male 102.9
Sample D Male 80.0
Substantia nigra
nTPM: 123.6
Samples: 4

Max nTPM: 146.8
Min nTPM: 104.6
Sample A Female 146.8
Sample B Female 104.6
Sample C Male 133.9
Sample D Male 108.9
Superior colliculi
nTPM: 161.9
Samples: 4

Max nTPM: 204.5
Min nTPM: 136.6
Sample A Female 163.6
Sample B Female 136.6
Sample C Male 204.5
Sample D Male 143.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 398.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 398.9
Samples: 4

Max nTPM: 416.0
Min nTPM: 376.9
Sample A Male 408.0
Sample B Male 376.9
Sample C Female 394.8
Sample D Female 416.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.6
67978674 Antisense, RP_040923_01_E08, Mouse strain C57BL/6J (56 days, male) 12.6

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