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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:243.1 nTPM
HPA:243.1 nTPM
GTEx:109.9 nTPM
FANTOM5:58.9 Scaled Tags Per Million
Pig:117.6 nTPM
Mouse:128.7 nTPM
Allen mouse:3.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 243.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 210.4
2586 Male, age 75, left hemisphere 273.2
2828 Female, age 72, unknown 251.6
1827 Male, age 72, unknown 211.8
2666 Male, age 74, left hemisphere 209.6
1870 Female, age 42, unknown 203.8
2219 Male, age 76, both hemispheres 198.2
1833 Male, age 53, unknown 196.8
2411 Female, age 72, unknown 193.8
1830 Male, age 51, unknown 191.2
2019 Male, age 18, unknown 174.0
Dorsal raphe nucleus
nTPM: 231.7
2016 Female, age 72, unknown 251.9
2047 Male, age 72, unknown 242.3
2298 Female, age 72, unknown 237.0
1828 Male, age 53, unknown 231.7
2750 Male, age 76, both hemispheres 195.6
Inferior colliculus
nTPM: 214.3
1848 Female, age 42, unknown 225.7
2849 Male, age 72, unknown 222.8
1890 Male, age 53, unknown 207.1
2097 Female, age 72, unknown 201.6
Median raphe nucleus
nTPM: 206.4
2220 Male, age 76, midline 206.4
Pedunculopontine tegmental nucleus
nTPM: 188.8
1921 Female, age 85, both hemispheres 197.5
2334 Male, age 80, both hemispheres 195.6
2338 Male, age 61, both hemispheres 173.1
Periaquaductal grey, anterior
nTPM: 227.2
1795 Male, age 51, unknown 236.0
2502 Female, age 75, unknown 225.0
1947 Male, age 18, unknown 220.4
Periaquaductal grey, dorsal
nTPM: 243.1
1840 Male, age 53, unknown 268.0
2850 Male, age 76, both hemispheres 259.9
1831 Male, age 72, unknown 224.9
2464 Female, age 72, unknown 219.8
Periaquaductal grey, lateral
nTPM: 237.6
2053 Male, age 18, unknown 266.4
2140 Male, age 76, both hemispheres 253.7
2272 Male, age 74, both hemispheres 192.6
Pretectal area
nTPM: 210.6
2825 Male, age 18, unknown 239.8
2407 Male, age 75, both hemispheres 230.9
2316 Male, age 76, right hemisphere 216.0
2224 Female, age 72, unknown 214.5
2273 Male, age 74, both hemispheres 210.7
1816 Male, age 51, unknown 206.7
1815 Male, age 53, unknown 205.5
1944 Female, age 72, unknown 205.3
2667 Female, age 75, unknown 202.3
1817 Female, age 42, unknown 201.3
2007 Male, age 72, unknown 183.7
Red nucleus
nTPM: 200.2
2503 Female, age 72, unknown 212.9
2769 Male, age 72, unknown 207.5
2588 Male, age 74, left hemisphere 206.6
2227 Male, age 72, unknown 205.9
1954 Female, age 42, unknown 205.5
2584 Male, age 75, left hemisphere 201.7
1821 Female, age 72, unknown 200.5
1904 Male, age 53, unknown 199.3
2725 Female, age 75, unknown 198.4
1865 Male, age 51, unknown 195.5
2823 Male, age 76, right hemisphere 192.0
2785 Male, age 18, unknown 177.1
Substantia nigra
nTPM: 208.7
2699 Male, age 18, unknown 246.5
1916 Female, age 42, unknown 219.7
2590 Female, age 75, unknown 219.0
2583 Male, age 75, right hemisphere 218.2
1851 Male, age 51, unknown 209.3
2665 Male, age 74, both hemispheres 208.2
1889 Female, age 72, unknown 197.0
2241 Male, age 72, unknown 192.8
1941 Male, age 53, unknown 191.7
2409 Female, age 72, unknown 184.9
Superior colliculus
nTPM: 225.2
2664 Male, age 75, both hemispheres 307.7
1995 Male, age 72, unknown 248.0
1796 Male, age 53, unknown 225.6
1839 Male, age 51, unknown 220.4
2261 Male, age 18, unknown 219.9
2668 Female, age 75, unknown 219.2
2087 Female, age 72, unknown 211.4
1913 Female, age 42, unknown 210.2
2587 Male, age 74, left hemisphere 205.6
1895 Male, age 76, right hemisphere 184.0
Ventral tegmental area
nTPM: 212.3
1942 Male, age 51, unknown 229.1
2021 Male, age 53, unknown 229.1
1915 Female, age 42, unknown 215.0
2410 Female, age 72, unknown 203.6
2223 Female, age 72, unknown 198.6
2218 Male, age 76, both hemispheres 198.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 109.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 109.9
Samples: 139

Max nTPM: 349.2
Min nTPM: 8.8
Std nTPM: 59.1
Median nTPM: 100.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 349.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 266.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 249.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 249.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 243.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 233.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 232.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 221.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 220.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 210.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 203.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 190.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 188.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 183.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 183.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 182.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 182.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 177.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 170.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 168.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 167.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 167.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 164.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 162.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 161.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 160.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 157.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 157.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 155.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 153.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 153.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 153.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 148.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 144.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 143.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 143.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 138.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 138.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 136.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 134.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 134.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 131.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 128.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 128.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 126.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 125.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 124.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 123.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 122.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 121.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 119.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 116.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 116.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 116.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 115.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 111.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 110.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 109.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 108.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 107.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 106.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 105.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 105.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 104.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 103.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 103.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 103.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 101.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 100.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 99.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 99.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 98.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 98.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 97.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 96.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 95.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 93.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 92.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 91.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 91.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 91.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 89.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 88.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 88.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 88.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 85.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 82.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 81.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 79.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 78.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 77.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 75.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 75.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 75.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 74.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 74.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 72.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 70.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 69.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 66.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 66.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 65.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 63.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 63.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 62.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 61.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 60.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 60.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 58.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 58.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 58.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 56.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 56.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 55.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 55.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 51.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 48.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 46.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 45.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 45.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 44.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 39.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 37.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 35.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 34.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 28.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 27.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 27.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 26.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 26.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 23.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 11.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 8.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 58.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 58.9
FF:10158-103A5 76 years, female 58.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 117.6
Pig sample Sample description nTPM
Midbrain
nTPM: 115.5
Samples: 4

Max nTPM: 150.4
Min nTPM: 81.2
Sample A Female 150.4
Sample B Female 122.9
Sample C Male 107.5
Sample D Male 81.2
Periaqueductal gray
nTPM: 117.6
Samples: 3

Max nTPM: 134.0
Min nTPM: 103.4
Sample B Female 134.0
Sample C Male 115.4
Sample D Male 103.4
Substantia nigra
nTPM: 115.9
Samples: 4

Max nTPM: 130.0
Min nTPM: 98.3
Sample A Female 130.0
Sample B Female 98.3
Sample C Male 109.7
Sample D Male 125.4
Superior colliculi
nTPM: 99.5
Samples: 4

Max nTPM: 116.6
Min nTPM: 56.0
Sample A Female 115.2
Sample B Female 56.0
Sample C Male 110.2
Sample D Male 116.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 128.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.7
Samples: 4

Max nTPM: 140.7
Min nTPM: 118.2
Sample A Male 140.7
Sample B Male 124.0
Sample C Female 118.2
Sample D Female 131.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.0
1770 Antisense, RP_040526_02_G02, Mouse strain C57BL/6J (56 days, male) 3.0
1771 Antisense, RP_040526_02_G02, Mouse strain C57BL/6J (56 days, male) 2.1

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