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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:78.3 nTPM
HPA:78.3 nTPM
GTEx:68.2 nTPM
FANTOM5:76.7 Scaled Tags Per Million
Pig:65.6 nTPM
Mouse:99.9 nTPM
Allen mouse:13.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 78.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 56.2
1827 Male, age 72, unknown 73.4
2411 Female, age 72, unknown 67.3
2666 Male, age 74, left hemisphere 65.8
1870 Female, age 42, unknown 64.1
1833 Male, age 53, unknown 58.7
2586 Male, age 75, left hemisphere 55.4
2219 Male, age 76, both hemispheres 52.7
2828 Female, age 72, unknown 51.2
1830 Male, age 51, unknown 46.7
2019 Male, age 18, unknown 26.8
Dorsal raphe nucleus
nTPM: 61.9
2298 Female, age 72, unknown 82.9
2047 Male, age 72, unknown 65.9
2750 Male, age 76, both hemispheres 56.2
1828 Male, age 53, unknown 55.7
2016 Female, age 72, unknown 48.7
Inferior colliculus
nTPM: 71.1
2849 Male, age 72, unknown 78.7
2097 Female, age 72, unknown 77.6
1848 Female, age 42, unknown 73.8
1890 Male, age 53, unknown 54.5
Median raphe nucleus
nTPM: 71.3
2220 Male, age 76, midline 71.3
Pedunculopontine tegmental nucleus
nTPM: 60.1
1921 Female, age 85, both hemispheres 73.0
2334 Male, age 80, both hemispheres 72.0
2338 Male, age 61, both hemispheres 35.3
Periaquaductal grey, anterior
nTPM: 78.3
1947 Male, age 18, unknown 90.5
1795 Male, age 51, unknown 73.8
2502 Female, age 75, unknown 70.6
Periaquaductal grey, dorsal
nTPM: 68.1
1840 Male, age 53, unknown 88.1
2850 Male, age 76, both hemispheres 63.4
1831 Male, age 72, unknown 60.5
2464 Female, age 72, unknown 60.2
Periaquaductal grey, lateral
nTPM: 65.9
2053 Male, age 18, unknown 73.7
2140 Male, age 76, both hemispheres 63.8
2272 Male, age 74, both hemispheres 60.1
Pretectal area
nTPM: 63.0
2825 Male, age 18, unknown 85.8
2224 Female, age 72, unknown 85.2
1816 Male, age 51, unknown 71.6
2667 Female, age 75, unknown 65.4
1944 Female, age 72, unknown 60.2
2273 Male, age 74, both hemispheres 59.0
2316 Male, age 76, right hemisphere 58.1
2007 Male, age 72, unknown 53.4
1815 Male, age 53, unknown 52.6
1817 Female, age 42, unknown 51.5
2407 Male, age 75, both hemispheres 50.3
Red nucleus
nTPM: 43.1
1821 Female, age 72, unknown 54.1
2584 Male, age 75, left hemisphere 49.4
2725 Female, age 75, unknown 47.7
2769 Male, age 72, unknown 45.6
1954 Female, age 42, unknown 45.3
2227 Male, age 72, unknown 45.0
2503 Female, age 72, unknown 43.7
2588 Male, age 74, left hemisphere 42.3
1904 Male, age 53, unknown 41.0
2823 Male, age 76, right hemisphere 36.2
1865 Male, age 51, unknown 35.9
2785 Male, age 18, unknown 31.0
Substantia nigra
nTPM: 53.9
1916 Female, age 42, unknown 68.6
2241 Male, age 72, unknown 63.0
1851 Male, age 51, unknown 58.6
1889 Female, age 72, unknown 55.1
2699 Male, age 18, unknown 53.7
2590 Female, age 75, unknown 52.3
2665 Male, age 74, both hemispheres 49.8
1941 Male, age 53, unknown 48.0
2583 Male, age 75, right hemisphere 46.8
2409 Female, age 72, unknown 43.6
Superior colliculus
nTPM: 57.2
1796 Male, age 53, unknown 76.3
2261 Male, age 18, unknown 74.7
1839 Male, age 51, unknown 67.1
1895 Male, age 76, right hemisphere 66.9
2087 Female, age 72, unknown 58.3
2664 Male, age 75, both hemispheres 55.3
2668 Female, age 75, unknown 54.3
2587 Male, age 74, left hemisphere 50.5
1913 Female, age 42, unknown 36.3
1995 Male, age 72, unknown 32.6
Ventral tegmental area
nTPM: 64.4
1915 Female, age 42, unknown 70.8
2218 Male, age 76, both hemispheres 68.1
2021 Male, age 53, unknown 64.0
2410 Female, age 72, unknown 63.4
1942 Male, age 51, unknown 61.3
2223 Female, age 72, unknown 59.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 68.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 68.2
Samples: 139

Max nTPM: 152.8
Min nTPM: 33.0
Std nTPM: 21.5
Median nTPM: 63.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 152.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 132.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 127.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 118.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 116.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 116.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 114.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 113.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 107.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 107.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 106.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 103.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 101.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 101.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 98.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 97.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 96.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 94.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 94.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 88.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 88.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 85.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 85.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 84.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 82.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 82.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 82.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 82.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 81.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 81.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 81.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 80.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 79.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 78.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 77.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 77.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 76.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 76.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 75.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 75.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 75.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 73.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 73.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 71.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 71.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 71.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 71.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 70.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 69.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 69.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 68.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 67.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 67.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 67.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 66.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 65.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 65.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 65.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 64.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 64.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 64.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 63.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 63.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 62.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 62.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 62.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 61.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 61.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 60.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 60.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 60.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 60.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 59.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 58.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 58.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 58.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 57.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 57.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 57.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 56.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 56.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 56.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 55.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 55.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 55.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 55.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 54.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 54.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 53.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 53.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 52.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 52.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 52.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 51.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 51.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 51.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 51.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 51.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 50.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 50.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 50.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 50.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 50.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 49.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 49.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 48.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 48.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 48.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 47.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 47.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 47.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 46.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 46.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 46.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 45.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 45.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 45.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 44.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 42.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 42.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 42.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 40.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 38.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 38.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 38.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 38.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 33.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 76.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 76.7
FF:10158-103A5 76 years, female 76.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 65.6
Pig sample Sample description nTPM
Midbrain
nTPM: 59.6
Samples: 4

Max nTPM: 80.7
Min nTPM: 38.6
Sample A Female 38.6
Sample B Female 45.7
Sample C Male 80.7
Sample D Male 73.4
Periaqueductal gray
nTPM: 51.0
Samples: 3

Max nTPM: 61.3
Min nTPM: 43.1
Sample B Female 48.6
Sample C Male 61.3
Sample D Male 43.1
Substantia nigra
nTPM: 52.1
Samples: 4

Max nTPM: 70.2
Min nTPM: 31.8
Sample A Female 70.2
Sample B Female 40.2
Sample C Male 66.3
Sample D Male 31.8
Superior colliculi
nTPM: 65.6
Samples: 4

Max nTPM: 74.0
Min nTPM: 50.1
Sample A Female 74.0
Sample B Female 50.1
Sample C Male 71.7
Sample D Male 66.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 99.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 99.9
Samples: 4

Max nTPM: 102.7
Min nTPM: 95.1
Sample A Male 95.1
Sample B Male 102.3
Sample C Female 102.7
Sample D Female 99.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.0
77620309 Antisense, RP_070205_01_A10, Mouse strain C57BL/6J (56 days, male) 14.3
355883 Antisense, RP_040617_01_F01, Mouse strain C57BL/6J (56 days, male) 11.6
293903 Antisense, RP_040617_01_F01, Mouse strain C57BL/6J (56 days, male) 10.6
77869130 Antisense, RP_070205_01_A10, Mouse strain C57BL/6J (56 days, male) 8.4

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