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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:500.0 nTPM
HPA:500.0 nTPM
GTEx:350.7 nTPM
FANTOM5:1152.7 Scaled Tags Per Million
Pig:192.2 nTPM
Mouse:141.6 nTPM
Allen mouse:7.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 500.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 352.8
2019 Male, age 18, unknown 435.7
1830 Male, age 51, unknown 432.7
1833 Male, age 53, unknown 398.6
1870 Female, age 42, unknown 380.7
2411 Female, age 72, unknown 372.2
2828 Female, age 72, unknown 348.3
2666 Male, age 74, left hemisphere 341.9
2586 Male, age 75, left hemisphere 332.1
1827 Male, age 72, unknown 254.2
2219 Male, age 76, both hemispheres 231.6
Dorsal raphe nucleus
nTPM: 269.7
2750 Male, age 76, both hemispheres 465.4
2016 Female, age 72, unknown 249.0
1828 Male, age 53, unknown 247.7
2047 Male, age 72, unknown 206.9
2298 Female, age 72, unknown 179.4
Inferior colliculus
nTPM: 236.1
1890 Male, age 53, unknown 257.3
2849 Male, age 72, unknown 252.4
1848 Female, age 42, unknown 250.2
2097 Female, age 72, unknown 184.5
Median raphe nucleus
nTPM: 289.6
2220 Male, age 76, midline 289.6
Pedunculopontine tegmental nucleus
nTPM: 349.7
2338 Male, age 61, both hemispheres 391.5
2334 Male, age 80, both hemispheres 380.1
1921 Female, age 85, both hemispheres 277.5
Periaquaductal grey, anterior
nTPM: 228.4
2502 Female, age 75, unknown 272.5
1947 Male, age 18, unknown 212.5
1795 Male, age 51, unknown 200.3
Periaquaductal grey, dorsal
nTPM: 197.2
2464 Female, age 72, unknown 258.5
1831 Male, age 72, unknown 206.2
2850 Male, age 76, both hemispheres 166.4
1840 Male, age 53, unknown 157.7
Periaquaductal grey, lateral
nTPM: 206.5
2272 Male, age 74, both hemispheres 249.7
2053 Male, age 18, unknown 212.5
2140 Male, age 76, both hemispheres 157.2
Pretectal area
nTPM: 256.6
1815 Male, age 53, unknown 333.8
2007 Male, age 72, unknown 322.3
1817 Female, age 42, unknown 311.0
2316 Male, age 76, right hemisphere 293.7
2407 Male, age 75, both hemispheres 278.2
2825 Male, age 18, unknown 244.1
1944 Female, age 72, unknown 218.9
2667 Female, age 75, unknown 213.1
1816 Male, age 51, unknown 212.4
2273 Male, age 74, both hemispheres 201.1
2224 Female, age 72, unknown 194.0
Red nucleus
nTPM: 500.0
2823 Male, age 76, right hemisphere 599.8
1865 Male, age 51, unknown 557.7
1904 Male, age 53, unknown 552.8
2785 Male, age 18, unknown 537.8
2769 Male, age 72, unknown 525.9
2588 Male, age 74, left hemisphere 513.2
2503 Female, age 72, unknown 510.2
1821 Female, age 72, unknown 499.7
2227 Male, age 72, unknown 499.6
1954 Female, age 42, unknown 438.6
2584 Male, age 75, left hemisphere 389.3
2725 Female, age 75, unknown 375.0
Substantia nigra
nTPM: 281.4
2590 Female, age 75, unknown 346.6
1889 Female, age 72, unknown 331.3
2583 Male, age 75, right hemisphere 312.7
1851 Male, age 51, unknown 305.8
2409 Female, age 72, unknown 294.6
2699 Male, age 18, unknown 278.5
2665 Male, age 74, both hemispheres 261.2
1941 Male, age 53, unknown 238.1
1916 Female, age 42, unknown 227.8
2241 Male, age 72, unknown 217.2
Superior colliculus
nTPM: 293.8
1995 Male, age 72, unknown 384.2
1913 Female, age 42, unknown 382.4
2587 Male, age 74, left hemisphere 332.6
1895 Male, age 76, right hemisphere 304.9
1839 Male, age 51, unknown 301.0
2668 Female, age 75, unknown 289.9
1796 Male, age 53, unknown 255.4
2087 Female, age 72, unknown 237.8
2664 Male, age 75, both hemispheres 228.2
2261 Male, age 18, unknown 221.8
Ventral tegmental area
nTPM: 317.5
2223 Female, age 72, unknown 424.9
2410 Female, age 72, unknown 386.5
2218 Male, age 76, both hemispheres 299.3
2021 Male, age 53, unknown 279.8
1942 Male, age 51, unknown 265.0
1915 Female, age 42, unknown 249.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 350.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 350.7
Samples: 139

Max nTPM: 871.4
Min nTPM: 115.4
Std nTPM: 145.4
Median nTPM: 319.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 871.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 788.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 742.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 669.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 652.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 632.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 629.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 628.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 619.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 601.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 600.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 587.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 583.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 580.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 578.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 576.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 574.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 555.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 527.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 517.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 489.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 489.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 476.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 473.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 460.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 458.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 455.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 450.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 449.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 448.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 447.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 441.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 435.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 433.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 432.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 432.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 432.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 428.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 427.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 416.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 413.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 396.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 394.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 387.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 378.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 377.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 375.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 372.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 372.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 370.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 368.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 366.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 366.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 363.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 362.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 361.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 358.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 344.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 342.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 341.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 341.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 338.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 337.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 337.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 336.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 336.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 327.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 325.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 324.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 319.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 318.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 318.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 314.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 313.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 312.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 299.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 297.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 297.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 297.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 296.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 295.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 294.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 293.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 292.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 290.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 290.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 288.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 283.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 282.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 280.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 279.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 277.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 275.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 273.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 271.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 270.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 269.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 269.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 267.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 262.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 262.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 260.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 256.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 251.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 251.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 250.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 245.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 242.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 242.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 240.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 239.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 231.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 230.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 228.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 223.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 219.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 213.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 212.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 196.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 196.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 194.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 192.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 189.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 189.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 186.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 183.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 182.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 181.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 177.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 176.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 174.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 171.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 170.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 154.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 141.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 123.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 118.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 117.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 115.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1152.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1152.7
FF:10158-103A5 76 years, female 1152.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 192.2
Pig sample Sample description nTPM
Midbrain
nTPM: 192.3
Samples: 4

Max nTPM: 442.4
Min nTPM: 84.2
Sample A Female 442.4
Sample B Female 147.4
Sample C Male 95.0
Sample D Male 84.2
Periaqueductal gray
nTPM: 110.0
Samples: 3

Max nTPM: 132.5
Min nTPM: 91.4
Sample B Female 132.5
Sample C Male 91.4
Sample D Male 106.2
Substantia nigra
nTPM: 171.5
Samples: 4

Max nTPM: 222.6
Min nTPM: 132.3
Sample A Female 194.0
Sample B Female 137.2
Sample C Male 132.3
Sample D Male 222.6
Superior colliculi
nTPM: 155.3
Samples: 4

Max nTPM: 188.4
Min nTPM: 140.3
Sample A Female 188.4
Sample B Female 143.0
Sample C Male 140.3
Sample D Male 149.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 141.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 141.6
Samples: 4

Max nTPM: 142.8
Min nTPM: 140.3
Sample A Male 141.5
Sample B Male 142.8
Sample C Female 140.3
Sample D Female 141.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.6
70429303 Antisense, RP_050614_01_D08, Mouse strain C57BL/6J (56 days, male) 7.6

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