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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:627.4 nTPM
HPA:627.4 nTPM
GTEx:493.0 nTPM
FANTOM5:653.7 Scaled Tags Per Million
Pig:662.0 nTPM
Mouse:657.4 nTPM
Allen mouse:26.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 627.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 500.9
2411 Female, age 72, unknown 645.8
1870 Female, age 42, unknown 576.8
1830 Male, age 51, unknown 574.2
2019 Male, age 18, unknown 557.7
1833 Male, age 53, unknown 550.7
2828 Female, age 72, unknown 456.8
2666 Male, age 74, left hemisphere 421.9
2586 Male, age 75, left hemisphere 414.9
1827 Male, age 72, unknown 413.2
2219 Male, age 76, both hemispheres 396.7
Dorsal raphe nucleus
nTPM: 423.9
2750 Male, age 76, both hemispheres 646.6
1828 Male, age 53, unknown 396.3
2016 Female, age 72, unknown 380.6
2047 Male, age 72, unknown 354.3
2298 Female, age 72, unknown 341.5
Inferior colliculus
nTPM: 392.5
1848 Female, age 42, unknown 408.2
1890 Male, age 53, unknown 397.6
2849 Male, age 72, unknown 384.7
2097 Female, age 72, unknown 379.6
Median raphe nucleus
nTPM: 405.8
2220 Male, age 76, midline 405.8
Pedunculopontine tegmental nucleus
nTPM: 469.7
2334 Male, age 80, both hemispheres 519.3
2338 Male, age 61, both hemispheres 445.4
1921 Female, age 85, both hemispheres 444.5
Periaquaductal grey, anterior
nTPM: 360.2
1947 Male, age 18, unknown 391.6
2502 Female, age 75, unknown 344.7
1795 Male, age 51, unknown 344.3
Periaquaductal grey, dorsal
nTPM: 329.5
2464 Female, age 72, unknown 403.8
1831 Male, age 72, unknown 346.0
1840 Male, age 53, unknown 295.6
2850 Male, age 76, both hemispheres 272.7
Periaquaductal grey, lateral
nTPM: 362.8
2272 Male, age 74, both hemispheres 427.0
2053 Male, age 18, unknown 383.2
2140 Male, age 76, both hemispheres 278.2
Pretectal area
nTPM: 393.0
2316 Male, age 76, right hemisphere 449.5
2407 Male, age 75, both hemispheres 448.6
1815 Male, age 53, unknown 448.1
2007 Male, age 72, unknown 426.0
1817 Female, age 42, unknown 414.9
2825 Male, age 18, unknown 397.6
2273 Male, age 74, both hemispheres 394.4
2224 Female, age 72, unknown 359.0
2667 Female, age 75, unknown 346.4
1944 Female, age 72, unknown 320.2
1816 Male, age 51, unknown 318.1
Red nucleus
nTPM: 627.4
1865 Male, age 51, unknown 697.2
1904 Male, age 53, unknown 680.8
2769 Male, age 72, unknown 672.9
1821 Female, age 72, unknown 669.5
2227 Male, age 72, unknown 657.1
2823 Male, age 76, right hemisphere 654.0
2503 Female, age 72, unknown 631.7
2785 Male, age 18, unknown 618.6
2588 Male, age 74, left hemisphere 596.1
1954 Female, age 42, unknown 586.5
2584 Male, age 75, left hemisphere 548.5
2725 Female, age 75, unknown 516.5
Substantia nigra
nTPM: 408.8
2583 Male, age 75, right hemisphere 546.9
2590 Female, age 75, unknown 517.9
1851 Male, age 51, unknown 443.7
1889 Female, age 72, unknown 440.5
2409 Female, age 72, unknown 410.4
1941 Male, age 53, unknown 385.1
1916 Female, age 42, unknown 353.5
2699 Male, age 18, unknown 350.2
2241 Male, age 72, unknown 336.2
2665 Male, age 74, both hemispheres 303.6
Superior colliculus
nTPM: 449.3
1913 Female, age 42, unknown 569.8
1995 Male, age 72, unknown 561.0
2587 Male, age 74, left hemisphere 504.1
1895 Male, age 76, right hemisphere 487.8
2668 Female, age 75, unknown 474.6
1839 Male, age 51, unknown 457.0
1796 Male, age 53, unknown 415.2
2261 Male, age 18, unknown 365.5
2087 Female, age 72, unknown 338.3
2664 Male, age 75, both hemispheres 319.3
Ventral tegmental area
nTPM: 480.6
2223 Female, age 72, unknown 695.4
2410 Female, age 72, unknown 537.0
2218 Male, age 76, both hemispheres 418.8
1942 Male, age 51, unknown 415.6
2021 Male, age 53, unknown 413.6
1915 Female, age 42, unknown 403.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 493.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 493.0
Samples: 139

Max nTPM: 1779.3
Min nTPM: 112.9
Std nTPM: 284.0
Median nTPM: 430.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1779.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1489.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1303.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1274.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1078.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1052.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1039.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1014.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1014.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1005.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1002.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 983.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 920.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 906.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 887.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 859.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 815.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 815.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 800.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 792.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 766.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 746.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 734.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 732.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 729.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 713.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 708.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 706.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 702.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 696.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 691.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 685.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 644.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 601.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 599.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 584.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 574.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 572.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 569.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 564.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 557.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 554.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 553.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 551.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 545.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 536.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 536.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 521.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 510.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 500.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 490.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 488.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 487.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 481.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 470.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 468.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 460.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 458.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 455.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 452.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 447.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 446.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 445.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 444.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 443.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 442.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 436.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 435.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 435.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 430.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 428.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 426.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 422.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 420.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 411.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 403.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 391.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 385.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 383.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 369.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 368.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 364.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 363.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 359.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 350.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 344.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 338.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 335.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 333.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 329.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 329.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 325.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 321.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 314.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 312.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 308.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 303.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 301.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 298.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 297.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 295.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 294.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 283.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 281.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 280.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 279.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 279.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 276.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 274.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 271.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 270.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 270.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 268.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 257.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 256.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 252.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 252.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 250.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 250.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 249.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 242.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 240.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 239.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 232.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 232.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 228.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 224.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 222.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 221.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 218.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 217.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 198.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 178.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 177.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 172.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 171.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 157.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 148.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 112.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 653.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 653.7
FF:10158-103A5 76 years, female 653.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 662.0
Pig sample Sample description nTPM
Midbrain
nTPM: 662.0
Samples: 4

Max nTPM: 1351.9
Min nTPM: 381.2
Sample A Female 1351.9
Sample B Female 492.1
Sample C Male 381.2
Sample D Male 422.9
Periaqueductal gray
nTPM: 362.3
Samples: 3

Max nTPM: 402.2
Min nTPM: 317.6
Sample B Female 402.2
Sample C Male 317.6
Sample D Male 367.1
Substantia nigra
nTPM: 526.6
Samples: 4

Max nTPM: 833.3
Min nTPM: 273.8
Sample A Female 563.7
Sample B Female 273.8
Sample C Male 435.6
Sample D Male 833.3
Superior colliculi
nTPM: 497.7
Samples: 4

Max nTPM: 630.6
Min nTPM: 251.9
Sample A Female 630.6
Sample B Female 251.9
Sample C Male 497.6
Sample D Male 610.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 657.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 657.4
Samples: 4

Max nTPM: 679.0
Min nTPM: 614.1
Sample A Male 667.3
Sample B Male 614.1
Sample C Female 669.2
Sample D Female 679.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 26.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 26.8
69015613 Antisense, RP_050315_01_C12, Mouse strain C57BL/6J (56 days, male) 26.8

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