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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:301.1 nTPM
HPA:301.1 nTPM
GTEx:178.9 nTPM
FANTOM5:84.1 Scaled Tags Per Million
Pig:199.0 nTPM
Mouse:403.5 nTPM
Allen mouse:14.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 301.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 288.1
2666 Male, age 74, left hemisphere 318.0
2586 Male, age 75, left hemisphere 307.1
2019 Male, age 18, unknown 298.3
1827 Male, age 72, unknown 297.9
2828 Female, age 72, unknown 292.5
2411 Female, age 72, unknown 284.9
2219 Male, age 76, both hemispheres 282.0
1870 Female, age 42, unknown 270.7
1833 Male, age 53, unknown 267.1
1830 Male, age 51, unknown 262.6
Dorsal raphe nucleus
nTPM: 277.8
2298 Female, age 72, unknown 289.1
2047 Male, age 72, unknown 282.1
2750 Male, age 76, both hemispheres 276.2
1828 Male, age 53, unknown 276.0
2016 Female, age 72, unknown 265.4
Inferior colliculus
nTPM: 277.5
2097 Female, age 72, unknown 293.9
1890 Male, age 53, unknown 278.0
1848 Female, age 42, unknown 273.1
2849 Male, age 72, unknown 265.0
Median raphe nucleus
nTPM: 281.3
2220 Male, age 76, midline 281.3
Pedunculopontine tegmental nucleus
nTPM: 278.2
1921 Female, age 85, both hemispheres 285.9
2334 Male, age 80, both hemispheres 280.9
2338 Male, age 61, both hemispheres 267.7
Periaquaductal grey, anterior
nTPM: 287.1
1795 Male, age 51, unknown 298.8
2502 Female, age 75, unknown 282.2
1947 Male, age 18, unknown 280.4
Periaquaductal grey, dorsal
nTPM: 272.5
1831 Male, age 72, unknown 280.1
1840 Male, age 53, unknown 273.5
2464 Female, age 72, unknown 270.9
2850 Male, age 76, both hemispheres 265.4
Periaquaductal grey, lateral
nTPM: 269.0
2053 Male, age 18, unknown 277.6
2272 Male, age 74, both hemispheres 265.2
2140 Male, age 76, both hemispheres 264.3
Pretectal area
nTPM: 301.1
1816 Male, age 51, unknown 350.2
1944 Female, age 72, unknown 339.0
2007 Male, age 72, unknown 332.0
1817 Female, age 42, unknown 330.8
1815 Male, age 53, unknown 313.3
2667 Female, age 75, unknown 292.7
2407 Male, age 75, both hemispheres 283.3
2224 Female, age 72, unknown 273.0
2825 Male, age 18, unknown 270.9
2273 Male, age 74, both hemispheres 264.9
2316 Male, age 76, right hemisphere 261.4
Red nucleus
nTPM: 278.5
2785 Male, age 18, unknown 295.5
2584 Male, age 75, left hemisphere 292.5
2588 Male, age 74, left hemisphere 282.3
1821 Female, age 72, unknown 282.0
2503 Female, age 72, unknown 279.9
1954 Female, age 42, unknown 278.6
2227 Male, age 72, unknown 274.2
1904 Male, age 53, unknown 273.4
2769 Male, age 72, unknown 272.4
2823 Male, age 76, right hemisphere 270.9
1865 Male, age 51, unknown 270.7
2725 Female, age 75, unknown 270.0
Substantia nigra
nTPM: 291.5
1916 Female, age 42, unknown 313.6
1941 Male, age 53, unknown 309.8
1889 Female, age 72, unknown 305.7
1851 Male, age 51, unknown 299.9
2583 Male, age 75, right hemisphere 297.2
2665 Male, age 74, both hemispheres 293.5
2590 Female, age 75, unknown 278.7
2241 Male, age 72, unknown 275.8
2409 Female, age 72, unknown 270.5
2699 Male, age 18, unknown 270.5
Superior colliculus
nTPM: 294.1
2668 Female, age 75, unknown 329.1
2087 Female, age 72, unknown 323.9
2261 Male, age 18, unknown 309.8
1796 Male, age 53, unknown 299.7
2664 Male, age 75, both hemispheres 291.9
1913 Female, age 42, unknown 282.8
1995 Male, age 72, unknown 280.7
1895 Male, age 76, right hemisphere 278.4
2587 Male, age 74, left hemisphere 274.4
1839 Male, age 51, unknown 270.4
Ventral tegmental area
nTPM: 285.9
2410 Female, age 72, unknown 298.3
1915 Female, age 42, unknown 294.1
2218 Male, age 76, both hemispheres 291.4
1942 Male, age 51, unknown 286.7
2021 Male, age 53, unknown 274.1
2223 Female, age 72, unknown 270.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 178.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 178.9
Samples: 139

Max nTPM: 383.2
Min nTPM: 49.6
Std nTPM: 66.3
Median nTPM: 170.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 383.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 363.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 362.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 357.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 354.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 346.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 330.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 315.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 301.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 282.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 260.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 258.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 257.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 255.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 252.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 250.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 250.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 249.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 249.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 246.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 241.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 239.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 238.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 236.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 233.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 231.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 230.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 230.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 228.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 223.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 221.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 220.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 217.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 216.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 216.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 212.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 210.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 209.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 208.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 208.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 207.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 206.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 205.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 204.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 203.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 201.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 200.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 200.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 199.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 199.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 197.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 197.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 196.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 196.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 195.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 194.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 193.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 190.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 189.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 189.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 187.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 186.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 184.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 181.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 177.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 176.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 175.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 173.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 171.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 170.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 166.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 164.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 163.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 161.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 158.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 158.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 157.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 157.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 156.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 156.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 151.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 150.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 148.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 147.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 147.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 145.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 145.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 145.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 142.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 142.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 142.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 140.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 140.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 139.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 139.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 139.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 139.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 138.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 137.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 137.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 137.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 136.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 135.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 133.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 133.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 132.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 131.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 130.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 129.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 126.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 125.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 124.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 123.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 123.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 122.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 117.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 114.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 113.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 111.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 110.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 110.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 109.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 109.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 106.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 102.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 102.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 101.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 99.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 94.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 92.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 86.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 84.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 81.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 81.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 78.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 77.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 69.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 49.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 84.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 84.1
FF:10158-103A5 76 years, female 84.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 199.0
Pig sample Sample description nTPM
Midbrain
nTPM: 198.7
Samples: 4

Max nTPM: 323.1
Min nTPM: 138.3
Sample A Female 155.7
Sample B Female 138.3
Sample C Male 323.1
Sample D Male 177.7
Periaqueductal gray
nTPM: 121.9
Samples: 3

Max nTPM: 149.5
Min nTPM: 102.3
Sample B Female 114.0
Sample C Male 149.5
Sample D Male 102.3
Substantia nigra
nTPM: 175.3
Samples: 4

Max nTPM: 243.3
Min nTPM: 96.8
Sample A Female 243.3
Sample B Female 134.5
Sample C Male 226.5
Sample D Male 96.8
Superior colliculi
nTPM: 199.0
Samples: 4

Max nTPM: 252.0
Min nTPM: 150.9
Sample A Female 210.7
Sample B Female 150.9
Sample C Male 252.0
Sample D Male 182.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 403.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 403.5
Samples: 4

Max nTPM: 406.6
Min nTPM: 401.6
Sample A Male 402.6
Sample B Male 401.6
Sample C Female 406.6
Sample D Female 403.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.2
68667946 Antisense, RP_050203_01_B05, Mouse strain C57BL/6J (56 days, male) 14.2

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