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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:317.3 nTPM
HPA:317.3 nTPM
GTEx:276.7 nTPM
FANTOM5:658.6 Scaled Tags Per Million
Pig:306.9 nTPM
Mouse:622.0 nTPM
Allen mouse:12.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 317.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 209.6
2411 Female, age 72, unknown 303.1
1830 Male, age 51, unknown 295.7
1833 Male, age 53, unknown 278.1
2019 Male, age 18, unknown 270.4
1870 Female, age 42, unknown 248.1
2828 Female, age 72, unknown 199.5
2219 Male, age 76, both hemispheres 155.8
1827 Male, age 72, unknown 135.3
2666 Male, age 74, left hemisphere 114.8
2586 Male, age 75, left hemisphere 95.7
Dorsal raphe nucleus
nTPM: 152.0
2750 Male, age 76, both hemispheres 338.4
2016 Female, age 72, unknown 141.2
1828 Male, age 53, unknown 135.3
2047 Male, age 72, unknown 75.5
2298 Female, age 72, unknown 69.5
Inferior colliculus
nTPM: 124.8
2849 Male, age 72, unknown 140.1
1848 Female, age 42, unknown 136.5
1890 Male, age 53, unknown 131.5
2097 Female, age 72, unknown 91.1
Median raphe nucleus
nTPM: 135.5
2220 Male, age 76, midline 135.5
Pedunculopontine tegmental nucleus
nTPM: 228.0
2338 Male, age 61, both hemispheres 281.5
2334 Male, age 80, both hemispheres 238.8
1921 Female, age 85, both hemispheres 163.6
Periaquaductal grey, anterior
nTPM: 85.2
1947 Male, age 18, unknown 103.1
1795 Male, age 51, unknown 81.0
2502 Female, age 75, unknown 71.5
Periaquaductal grey, dorsal
nTPM: 75.6
2464 Female, age 72, unknown 142.7
1831 Male, age 72, unknown 86.0
2850 Male, age 76, both hemispheres 37.1
1840 Male, age 53, unknown 36.7
Periaquaductal grey, lateral
nTPM: 104.5
2272 Male, age 74, both hemispheres 166.9
2053 Male, age 18, unknown 101.2
2140 Male, age 76, both hemispheres 45.4
Pretectal area
nTPM: 121.6
2316 Male, age 76, right hemisphere 187.7
1815 Male, age 53, unknown 187.6
2407 Male, age 75, both hemispheres 173.2
1817 Female, age 42, unknown 137.1
2273 Male, age 74, both hemispheres 136.8
2007 Male, age 72, unknown 123.5
2825 Male, age 18, unknown 122.4
2224 Female, age 72, unknown 95.7
2667 Female, age 75, unknown 62.3
1944 Female, age 72, unknown 61.3
1816 Male, age 51, unknown 49.9
Red nucleus
nTPM: 317.3
2823 Male, age 76, right hemisphere 413.4
1904 Male, age 53, unknown 372.2
1865 Male, age 51, unknown 372.1
1821 Female, age 72, unknown 370.4
2227 Male, age 72, unknown 341.2
2769 Male, age 72, unknown 340.1
2725 Female, age 75, unknown 304.4
2785 Male, age 18, unknown 299.5
1954 Female, age 42, unknown 298.4
2503 Female, age 72, unknown 280.7
2588 Male, age 74, left hemisphere 221.3
2584 Male, age 75, left hemisphere 193.3
Substantia nigra
nTPM: 147.0
2590 Female, age 75, unknown 246.1
2583 Male, age 75, right hemisphere 191.6
1851 Male, age 51, unknown 177.1
1889 Female, age 72, unknown 169.9
2409 Female, age 72, unknown 159.5
2699 Male, age 18, unknown 145.0
1941 Male, age 53, unknown 120.0
1916 Female, age 42, unknown 103.7
2241 Male, age 72, unknown 95.7
2665 Male, age 74, both hemispheres 61.8
Superior colliculus
nTPM: 168.4
1995 Male, age 72, unknown 271.0
1913 Female, age 42, unknown 252.3
1895 Male, age 76, right hemisphere 245.6
2587 Male, age 74, left hemisphere 191.4
1839 Male, age 51, unknown 181.3
2668 Female, age 75, unknown 177.0
1796 Male, age 53, unknown 130.3
2087 Female, age 72, unknown 90.2
2261 Male, age 18, unknown 74.4
2664 Male, age 75, both hemispheres 70.7
Ventral tegmental area
nTPM: 196.5
2223 Female, age 72, unknown 369.8
2410 Female, age 72, unknown 237.6
2218 Male, age 76, both hemispheres 166.4
1942 Male, age 51, unknown 143.1
1915 Female, age 42, unknown 135.9
2021 Male, age 53, unknown 126.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 276.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 276.7
Samples: 139

Max nTPM: 1225.3
Min nTPM: 48.8
Std nTPM: 186.3
Median nTPM: 215.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1225.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 870.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 850.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 806.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 785.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 730.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 715.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 679.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 613.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 607.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 590.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 558.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 545.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 515.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 473.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 467.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 444.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 440.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 427.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 422.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 417.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 410.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 397.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 392.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 390.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 390.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 382.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 374.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 372.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 371.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 363.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 362.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 352.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 351.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 351.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 337.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 334.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 331.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 326.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 324.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 322.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 316.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 312.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 305.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 299.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 295.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 294.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 291.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 288.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 279.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 275.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 275.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 274.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 274.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 270.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 268.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 261.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 259.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 256.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 256.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 255.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 238.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 234.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 224.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 222.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 217.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 217.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 217.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 216.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 215.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 214.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 214.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 214.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 214.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 213.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 212.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 210.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 210.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 210.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 209.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 209.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 201.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 200.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 200.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 195.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 192.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 192.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 189.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 187.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 186.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 183.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 181.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 179.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 179.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 179.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 176.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 175.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 166.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 164.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 161.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 161.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 156.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 153.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 152.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 150.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 145.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 144.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 144.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 141.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 141.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 140.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 134.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 133.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 132.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 129.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 128.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 127.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 124.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 124.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 122.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 122.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 121.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 119.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 117.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 115.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 114.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 107.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 106.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 102.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 98.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 96.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 94.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 88.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 78.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 75.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 71.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 53.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 48.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 658.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 658.6
FF:10158-103A5 76 years, female 658.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 306.9
Pig sample Sample description nTPM
Midbrain
nTPM: 306.9
Samples: 4

Max nTPM: 694.5
Min nTPM: 135.4
Sample A Female 694.5
Sample B Female 241.8
Sample C Male 135.4
Sample D Male 155.8
Periaqueductal gray
nTPM: 156.7
Samples: 3

Max nTPM: 186.7
Min nTPM: 122.0
Sample B Female 186.7
Sample C Male 122.0
Sample D Male 161.5
Substantia nigra
nTPM: 285.7
Samples: 4

Max nTPM: 502.0
Min nTPM: 145.6
Sample A Female 278.8
Sample B Female 145.6
Sample C Male 216.3
Sample D Male 502.0
Superior colliculi
nTPM: 215.9
Samples: 4

Max nTPM: 278.8
Min nTPM: 90.3
Sample A Female 278.8
Sample B Female 90.3
Sample C Male 219.1
Sample D Male 275.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 622.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 622.0
Samples: 4

Max nTPM: 685.4
Min nTPM: 524.2
Sample A Male 603.2
Sample B Male 524.2
Sample C Female 675.2
Sample D Female 685.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.3
69736418 Antisense, RP_050503_04_G05, Mouse strain C57BL/6J (56 days, male) 12.3

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