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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:115.7 nTPM
HPA:115.7 nTPM
FANTOM5:249.6 Scaled Tags Per Million
Pig:67.0 nTPM
Allen mouse:14.3 Expression energy

PONS - Annotated protein expression
Pending normal tissue analysis

PONS - HPA Brain RNA-seq
Max nTPM 115.7
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 58.7
1984 Male, age 76, both hemispheres 86.2
2301 Female, age 85, both hemispheres 59.4
2188 Female, age 91, both hemispheres 54.5
2090 Male, age 80, both hemispheres 34.9
Dorsal cochlear nucleus
nTPM: 55.4
2802 Male, age 74, right hemisphere 78.1
2370 Male, age 61, both hemispheres 58.9
2378 Male, age 80, both hemispheres 54.7
2187 Female, age 91, both hemispheres 42.9
2058 Male, age 76, both hemispheres 42.6
Dorsal tegmental nucleus
nTPM: 43.5
2083 Male, age 80, both hemispheres 55.7
1936 Male, age 76, left hemisphere 43.3
2358 Male, age 61, both hemispheres 40.3
2326 Male, age 74, both hemispheres 34.5
Dorsolateral tegmental area
nTPM: 35.6
2654 Male, age 80, both hemispheres 56.6
2751 Female, age 85, both hemispheres 38.8
2337 Male, age 61, both hemispheres 32.3
2141 Male, age 76, both hemispheres 27.0
2360 Male, age 74, both hemispheres 23.6
Kolliker-Fuse nucleus
nTPM: 64.7
2793 Female, age 91, left hemisphere 80.2
2163 Male, age 80, both hemispheres 79.2
2315 Male, age 76, right hemisphere 34.8
Lateral lemniscal nuclei
nTPM: 103.7
2453 Male, age 74, right hemisphere 133.7
2169 Male, age 76, both hemispheres 114.5
2036 Male, age 80, both hemispheres 101.0
2746 Female, age 85, left hemisphere 86.4
2320 Female, age 91, left hemisphere 82.7
Lateral parabrachial nucleus
nTPM: 58.7
2139 Female, age 85, right hemisphere 93.6
2013 Male, age 80, both hemispheres 56.3
2790 Male, age 61, both hemispheres 56.3
2792 Male, age 76, both hemispheres 28.7
Lateral vestibular nucleus
nTPM: 64.6
2184 Male, age 76, both hemispheres 83.0
2311 Male, age 80, both hemispheres 46.2
Locus coeruleus
nTPM: 19.8
2123 Female, age 91, both hemispheres 31.8
2720 Male, age 74, both hemispheres 28.0
2162 Male, age 80, both hemispheres 22.0
2317 Female, age 72, unknown 17.4
1980 Male, age 76, both hemispheres 14.3
2014 Male, age 55, unknown 14.0
2788 Male, age 74, unknown 11.4
Medial olivary nucleus
nTPM: 28.0
2851 Male, age 80, both hemispheres 45.5
2138 Female, age 91, both hemispheres 23.8
1962 Male, age 76, both hemispheres 22.6
1943 Male, age 61, both hemispheres 20.2
Medial parabrachial nucleus
nTPM: 53.4
2854 Male, age 80, both hemispheres 70.7
2156 Male, age 61, both hemispheres 58.7
2463 Female, age 85, right hemisphere 50.6
2170 Female, age 91, both hemispheres 44.9
2786 Male, age 76, both hemispheres 42.0
Medial periolivary nuclei
nTPM: 93.5
2171 Female, age 85, both hemispheres 145.1
2063 Male, age 76, both hemispheres 106.4
2791 Male, age 74, right hemisphere 79.7
2458 Female, age 91, both hemispheres 79.2
2081 Male, age 80, both hemispheres 56.9
Motor facial nucleus
nTPM: 95.5
2062 Male, age 76, both hemispheres 119.1
2795 Female, age 91, both hemispheres 105.1
2365 Male, age 74, right hemisphere 97.8
2327 Male, age 80, both hemispheres 96.4
2697 Female, age 85, both hemispheres 92.7
2126 Male, age 61, both hemispheres 61.7
Motor trigeminal nucleus
nTPM: 67.8
2560 Male, age 74, both hemispheres 103.1
2079 Male, age 80, both hemispheres 83.6
2321 Female, age 91, both hemispheres 56.2
2335 Male, age 61, both hemispheres 50.0
2309 Male, age 76, both hemispheres 46.0
Nuclei of the trapezoid body
nTPM: 115.7
2159 Male, age 61, both hemispheres 163.5
2735 Female, age 85, both hemispheres 126.8
1983 Male, age 76, both hemispheres 106.2
2368 Female, age 91, both hemispheres 95.8
2166 Male, age 80, both hemispheres 86.2
Paramedian reticular nucleus
nTPM: 58.4
2050 Female, age 85, both hemispheres 107.4
2057 Male, age 80, both hemispheres 50.3
2313 Male, age 61, both hemispheres 45.9
2052 Male, age 76, both hemispheres 30.2
Pontine nuclei
nTPM: 108.5
1863 Male, age 55, unknown 162.3
2787 Female, age 85, both hemispheres 161.9
2727 Male, age 61, right hemisphere 119.2
1968 Male, age 76, left hemisphere 107.4
2109 Female, age 72, unknown 101.8
2454 Male, age 74, left hemisphere 83.6
2115 Male, age 80, left hemisphere 75.5
2319 Female, age 91, both hemispheres 56.1
Pontine raphe nucleus
nTPM: 51.6
2122 Female, age 85, midline 81.5
2853 Male, age 76, midline 21.7
Posteroventral cochlear nucleus
nTPM: 49.6
2752 Female, age 85, both hemispheres 68.1
2371 Male, age 61, both hemispheres 55.0
2070 Male, age 76, both hemispheres 51.2
2341 Male, age 80, both hemispheres 45.4
2135 Female, age 91, both hemispheres 28.1
Principal sensory trigeminal nucleus
nTPM: 94.9
2158 Male, age 61, both hemispheres 147.4
2008 Male, age 80, left hemisphere 90.3
2324 Male, age 76, both hemispheres 73.3
2367 Female, age 91, left hemisphere 68.6
Reticular pontine nucleus, caudal
nTPM: 80.6
2332 Male, age 80, right hemisphere 124.7
2092 Male, age 76, both hemispheres 78.9
2457 Female, age 91, both hemispheres 76.1
2559 Male, age 74, both hemispheres 42.8
Reticular pontine nucleus, oral
nTPM: 59.5
2361 Male, age 74, both hemispheres 83.1
2012 Female, age 85, both hemispheres 73.0
2366 Female, age 91, both hemispheres 60.0
1939 Male, age 80, both hemispheres 44.9
2167 Male, age 76, both hemispheres 36.8
Reticulotegmental nucleus
nTPM: 75.7
2452 Male, age 74, both hemispheres 86.8
2333 Male, age 80, both hemispheres 80.7
2322 Female, age 91, both hemispheres 73.3
2325 Male, age 76, both hemispheres 62.2
Spinal trigeminal nucleus, oral
nTPM: 69.8
2164 Male, age 80, both hemispheres 86.9
2737 Female, age 85, both hemispheres 80.8
1978 Male, age 76, both hemispheres 41.8
Subcoeruleus area
nTPM: 47.5
2089 Male, age 76, left hemisphere 69.9
1958 Male, age 80, both hemispheres 62.6
2323 Female, age 91, left hemisphere 40.0
2451 Male, age 74, both hemispheres 34.0
2369 Female, age 85, left hemisphere 31.2
Superior olive
nTPM: 87.6
1875 Female, age 85, both hemispheres 106.5
2561 Female, age 91, both hemispheres 100.1
2329 Male, age 80, right hemisphere 90.4
2364 Male, age 74, right hemisphere 70.6
2020 Male, age 76, both hemispheres 70.4
Superior vestibular nucleus
nTPM: 38.0
2015 Male, age 80, both hemispheres 50.8
2061 Male, age 76, both hemispheres 36.8
2383 Male, age 74, both hemispheres 26.4
Ventral periolivary nuclei
nTPM: 93.8
2165 Male, age 80, both hemispheres 114.9
2130 Female, age 85, both hemispheres 103.1
2794 Female, age 91, left hemisphere 96.3
2023 Male, age 76, both hemispheres 60.9
Ventrolateral tegmental area, A5 NE cell group
nTPM: 79.2
2449 Male, age 74, both hemispheres 116.7
2161 Male, age 80, both hemispheres 84.4
2840 Female, age 85, both hemispheres 84.0
1959 Male, age 76, both hemispheres 83.5
2456 Female, age 91, both hemispheres 81.0
2359 Male, age 61, both hemispheres 25.5

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 249.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 66.6
FF:10182-103D2 60 years, female 98.1
FF:10165-103B3 76 years, female 35.1
Pons
Scaled Tags Per Million: 249.6
FF:10033-101E6 18-54 years, mixed 249.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 67.0
Pig sample Sample description nTPM
Pons
nTPM: 67.0
Samples: 4

Max nTPM: 113.3
Min nTPM: 20.5
Sample A Female 113.3
Sample B Female 20.5
Sample C Male 23.7
Sample D Male 110.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.3
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 14.3
77454673 Antisense, RP_070129_01_C06, Mouse strain C57BL/6J (56 days, male) 14.3

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.