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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:156.9 nTPM
HPA:156.9 nTPM
GTEx:182.4 nTPM
FANTOM5:93.2 Scaled Tags Per Million
Pig:207.9 nTPM
Mouse:191.0 nTPM
Allen mouse:15.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 156.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 153.6
2586 Male, age 75, left hemisphere 169.8
2019 Male, age 18, unknown 165.1
2411 Female, age 72, unknown 159.9
2666 Male, age 74, left hemisphere 159.9
1827 Male, age 72, unknown 156.1
1870 Female, age 42, unknown 155.3
2828 Female, age 72, unknown 152.7
1830 Male, age 51, unknown 147.2
1833 Male, age 53, unknown 143.9
2219 Male, age 76, both hemispheres 126.2
Dorsal raphe nucleus
nTPM: 144.5
2750 Male, age 76, both hemispheres 149.2
2298 Female, age 72, unknown 147.6
1828 Male, age 53, unknown 146.6
2047 Male, age 72, unknown 139.7
2016 Female, age 72, unknown 139.5
Inferior colliculus
nTPM: 146.4
2097 Female, age 72, unknown 152.6
1848 Female, age 42, unknown 147.0
1890 Male, age 53, unknown 143.8
2849 Male, age 72, unknown 142.3
Median raphe nucleus
nTPM: 135.1
2220 Male, age 76, midline 135.1
Pedunculopontine tegmental nucleus
nTPM: 139.2
2334 Male, age 80, both hemispheres 147.4
1921 Female, age 85, both hemispheres 138.6
2338 Male, age 61, both hemispheres 131.5
Periaquaductal grey, anterior
nTPM: 145.4
2502 Female, age 75, unknown 147.5
1795 Male, age 51, unknown 145.5
1947 Male, age 18, unknown 143.2
Periaquaductal grey, dorsal
nTPM: 137.5
1840 Male, age 53, unknown 141.5
1831 Male, age 72, unknown 140.2
2464 Female, age 72, unknown 137.5
2850 Male, age 76, both hemispheres 130.7
Periaquaductal grey, lateral
nTPM: 134.9
2053 Male, age 18, unknown 138.4
2140 Male, age 76, both hemispheres 134.4
2272 Male, age 74, both hemispheres 131.9
Pretectal area
nTPM: 150.1
2007 Male, age 72, unknown 164.9
1817 Female, age 42, unknown 164.5
1816 Male, age 51, unknown 163.2
1815 Male, age 53, unknown 159.2
1944 Female, age 72, unknown 151.2
2667 Female, age 75, unknown 146.6
2825 Male, age 18, unknown 145.1
2407 Male, age 75, both hemispheres 143.4
2273 Male, age 74, both hemispheres 138.9
2316 Male, age 76, right hemisphere 138.6
2224 Female, age 72, unknown 135.6
Red nucleus
nTPM: 156.9
1821 Female, age 72, unknown 171.4
2588 Male, age 74, left hemisphere 164.6
2785 Male, age 18, unknown 160.6
1954 Female, age 42, unknown 157.6
1865 Male, age 51, unknown 157.3
2584 Male, age 75, left hemisphere 155.9
1904 Male, age 53, unknown 155.8
2769 Male, age 72, unknown 155.6
2227 Male, age 72, unknown 155.5
2503 Female, age 72, unknown 152.6
2823 Male, age 76, right hemisphere 149.2
2725 Female, age 75, unknown 147.1
Substantia nigra
nTPM: 149.1
2583 Male, age 75, right hemisphere 161.5
1889 Female, age 72, unknown 158.4
2590 Female, age 75, unknown 154.1
1851 Male, age 51, unknown 153.0
2665 Male, age 74, both hemispheres 152.8
1916 Female, age 42, unknown 151.9
1941 Male, age 53, unknown 150.3
2241 Male, age 72, unknown 140.5
2699 Male, age 18, unknown 134.9
2409 Female, age 72, unknown 133.9
Superior colliculus
nTPM: 151.1
2664 Male, age 75, both hemispheres 157.2
2668 Female, age 75, unknown 155.8
2261 Male, age 18, unknown 154.2
1895 Male, age 76, right hemisphere 151.3
2087 Female, age 72, unknown 150.7
1995 Male, age 72, unknown 150.6
1796 Male, age 53, unknown 150.1
1913 Female, age 42, unknown 149.4
2587 Male, age 74, left hemisphere 146.3
1839 Male, age 51, unknown 145.1
Ventral tegmental area
nTPM: 145.9
2410 Female, age 72, unknown 156.6
2223 Female, age 72, unknown 156.0
1915 Female, age 42, unknown 147.1
2021 Male, age 53, unknown 141.2
1942 Male, age 51, unknown 139.9
2218 Male, age 76, both hemispheres 134.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 182.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 182.4
Samples: 139

Max nTPM: 282.8
Min nTPM: 141.4
Std nTPM: 26.6
Median nTPM: 178.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 282.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 277.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 256.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 253.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 239.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 231.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 230.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 229.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 227.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 224.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 222.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 216.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 215.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 213.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 213.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 211.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 211.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 210.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 209.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 208.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 207.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 205.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 205.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 205.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 204.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 203.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 202.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 201.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 199.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 199.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 198.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 198.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 198.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 198.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 196.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 196.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 196.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 196.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 195.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 195.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 194.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 193.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 192.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 192.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 191.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 191.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 190.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 189.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 189.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 188.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 188.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 187.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 187.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 186.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 186.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 186.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 185.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 183.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 183.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 182.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 182.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 181.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 181.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 180.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 179.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 179.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 179.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 178.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 178.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 178.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 178.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 177.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 177.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 175.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 174.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 174.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 174.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 173.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 173.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 172.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 171.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 171.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 171.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 170.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 170.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 170.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 170.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 170.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 169.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 169.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 168.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 168.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 168.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 168.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 166.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 166.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 165.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 165.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 165.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 164.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 163.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 163.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 162.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 162.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 161.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 161.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 161.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 160.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 159.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 159.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 159.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 157.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 156.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 156.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 156.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 156.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 155.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 155.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 154.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 153.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 153.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 152.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 151.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 150.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 150.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 149.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 148.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 148.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 146.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 145.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 145.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 144.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 143.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 142.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 141.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 141.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 93.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 93.2
FF:10158-103A5 76 years, female 93.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 207.9
Pig sample Sample description nTPM
Midbrain
nTPM: 207.9
Samples: 4

Max nTPM: 273.8
Min nTPM: 178.5
Sample A Female 273.8
Sample B Female 178.5
Sample C Male 195.1
Sample D Male 184.1
Periaqueductal gray
nTPM: 167.7
Samples: 3

Max nTPM: 183.6
Min nTPM: 152.5
Sample B Female 167.1
Sample C Male 183.6
Sample D Male 152.5
Substantia nigra
nTPM: 179.8
Samples: 4

Max nTPM: 209.8
Min nTPM: 147.9
Sample A Female 209.8
Sample B Female 147.9
Sample C Male 183.7
Sample D Male 177.7
Superior colliculi
nTPM: 197.4
Samples: 4

Max nTPM: 223.7
Min nTPM: 154.0
Sample A Female 223.7
Sample B Female 154.0
Sample C Male 210.3
Sample D Male 201.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 191.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 191.0
Samples: 4

Max nTPM: 196.6
Min nTPM: 185.0
Sample A Male 196.6
Sample B Male 186.0
Sample C Female 196.2
Sample D Female 185.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.8
513227 Antisense, RP_040810_01_C03, Mouse strain C57BL/6J (56 days, male) 15.8

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