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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:412.3 nTPM
HPA:412.3 nTPM
GTEx:419.5 nTPM
FANTOM5:312.4 Scaled Tags Per Million
Pig:72.5 nTPM
Mouse:123.2 nTPM
Allen mouse:4.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 412.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 391.5
1870 Female, age 42, unknown 399.3
1827 Male, age 72, unknown 397.3
2586 Male, age 75, left hemisphere 393.0
2219 Male, age 76, both hemispheres 392.9
2666 Male, age 74, left hemisphere 392.5
2019 Male, age 18, unknown 388.9
2828 Female, age 72, unknown 388.7
1830 Male, age 51, unknown 388.5
1833 Male, age 53, unknown 387.3
2411 Female, age 72, unknown 386.4
Dorsal raphe nucleus
nTPM: 389.9
2047 Male, age 72, unknown 396.0
1828 Male, age 53, unknown 393.7
2750 Male, age 76, both hemispheres 393.2
2298 Female, age 72, unknown 388.9
2016 Female, age 72, unknown 377.5
Inferior colliculus
nTPM: 392.0
2849 Male, age 72, unknown 400.3
1890 Male, age 53, unknown 390.3
1848 Female, age 42, unknown 389.3
2097 Female, age 72, unknown 388.0
Median raphe nucleus
nTPM: 412.3
2220 Male, age 76, midline 412.3
Pedunculopontine tegmental nucleus
nTPM: 407.9
2338 Male, age 61, both hemispheres 424.6
2334 Male, age 80, both hemispheres 404.9
1921 Female, age 85, both hemispheres 394.1
Periaquaductal grey, anterior
nTPM: 390.1
1795 Male, age 51, unknown 394.4
1947 Male, age 18, unknown 390.6
2502 Female, age 75, unknown 385.3
Periaquaductal grey, dorsal
nTPM: 386.1
2850 Male, age 76, both hemispheres 403.2
1840 Male, age 53, unknown 385.4
1831 Male, age 72, unknown 382.9
2464 Female, age 72, unknown 372.7
Periaquaductal grey, lateral
nTPM: 384.7
2140 Male, age 76, both hemispheres 388.9
2053 Male, age 18, unknown 384.7
2272 Male, age 74, both hemispheres 380.5
Pretectal area
nTPM: 396.9
1817 Female, age 42, unknown 412.0
1816 Male, age 51, unknown 405.1
1944 Female, age 72, unknown 405.0
2007 Male, age 72, unknown 403.2
2667 Female, age 75, unknown 401.1
2407 Male, age 75, both hemispheres 400.7
1815 Male, age 53, unknown 397.2
2825 Male, age 18, unknown 390.5
2224 Female, age 72, unknown 387.8
2273 Male, age 74, both hemispheres 384.1
2316 Male, age 76, right hemisphere 379.0
Red nucleus
nTPM: 398.0
2725 Female, age 75, unknown 405.9
1821 Female, age 72, unknown 403.1
1865 Male, age 51, unknown 402.9
2584 Male, age 75, left hemisphere 400.1
2785 Male, age 18, unknown 398.4
2769 Male, age 72, unknown 398.1
1904 Male, age 53, unknown 397.4
2503 Female, age 72, unknown 396.7
2227 Male, age 72, unknown 396.3
1954 Female, age 42, unknown 394.3
2588 Male, age 74, left hemisphere 392.2
2823 Male, age 76, right hemisphere 391.2
Substantia nigra
nTPM: 398.3
1916 Female, age 42, unknown 421.7
2699 Male, age 18, unknown 411.1
1889 Female, age 72, unknown 405.5
1851 Male, age 51, unknown 404.6
1941 Male, age 53, unknown 401.5
2665 Male, age 74, both hemispheres 399.5
2409 Female, age 72, unknown 392.2
2583 Male, age 75, right hemisphere 383.7
2590 Female, age 75, unknown 383.0
2241 Male, age 72, unknown 379.9
Superior colliculus
nTPM: 392.9
2587 Male, age 74, left hemisphere 404.7
2668 Female, age 75, unknown 401.2
1796 Male, age 53, unknown 399.1
1913 Female, age 42, unknown 398.0
1895 Male, age 76, right hemisphere 392.8
2087 Female, age 72, unknown 390.7
1995 Male, age 72, unknown 388.4
2261 Male, age 18, unknown 387.8
2664 Male, age 75, both hemispheres 386.3
1839 Male, age 51, unknown 380.5
Ventral tegmental area
nTPM: 397.2
2223 Female, age 72, unknown 408.1
2218 Male, age 76, both hemispheres 403.9
1915 Female, age 42, unknown 403.5
2410 Female, age 72, unknown 390.6
1942 Male, age 51, unknown 389.4
2021 Male, age 53, unknown 387.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 419.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 419.5
Samples: 139

Max nTPM: 962.0
Min nTPM: 239.0
Std nTPM: 95.3
Median nTPM: 408.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 962.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 741.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 678.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 631.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 616.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 609.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 591.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 584.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 569.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 565.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 563.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 555.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 552.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 534.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 517.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 516.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 513.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 507.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 503.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 500.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 496.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 495.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 494.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 488.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 486.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 480.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 473.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 470.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 465.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 465.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 464.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 461.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 461.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 461.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 460.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 459.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 455.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 454.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 454.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 450.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 444.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 444.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 444.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 444.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 441.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 435.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 434.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 431.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 430.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 428.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 428.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 428.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 427.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 425.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 423.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 421.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 421.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 420.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 418.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 416.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 415.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 414.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 414.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 414.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 414.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 412.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 411.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 410.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 409.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 408.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 407.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 406.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 402.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 399.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 398.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 398.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 397.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 396.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 394.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 393.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 391.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 390.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 390.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 389.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 388.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 388.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 387.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 386.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 380.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 379.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 375.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 375.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 374.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 373.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 370.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 364.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 364.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 360.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 358.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 357.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 356.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 356.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 356.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 355.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 355.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 355.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 354.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 353.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 351.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 351.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 349.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 349.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 348.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 348.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 347.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 347.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 346.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 346.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 345.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 343.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 338.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 331.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 329.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 328.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 327.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 322.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 318.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 314.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 310.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 309.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 307.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 304.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 303.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 295.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 289.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 281.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 270.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 269.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 239.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 312.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 312.4
FF:10158-103A5 76 years, female 312.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.5
Pig sample Sample description nTPM
Midbrain
nTPM: 72.5
Samples: 4

Max nTPM: 117.9
Min nTPM: 51.4
Sample A Female 117.9
Sample B Female 57.3
Sample C Male 63.5
Sample D Male 51.4
Periaqueductal gray
nTPM: 52.2
Samples: 3

Max nTPM: 59.5
Min nTPM: 46.3
Sample B Female 46.3
Sample C Male 59.5
Sample D Male 50.8
Substantia nigra
nTPM: 64.7
Samples: 4

Max nTPM: 79.3
Min nTPM: 47.6
Sample A Female 79.3
Sample B Female 47.6
Sample C Male 70.9
Sample D Male 60.9
Superior colliculi
nTPM: 69.3
Samples: 4

Max nTPM: 84.0
Min nTPM: 54.6
Sample A Female 84.0
Sample B Female 54.6
Sample C Male 71.5
Sample D Male 67.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 123.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 123.2
Samples: 4

Max nTPM: 138.1
Min nTPM: 104.3
Sample A Male 138.1
Sample B Male 104.3
Sample C Female 114.9
Sample D Female 135.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.0
68117986 Antisense, RP_040929_01_H04, Mouse strain C57BL/6J (56 days, male) 4.0

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