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RPL28
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:879.5 nTPM
HPA:879.5 nTPM
GTEx:1296.0 nTPM
FANTOM5:506.9 Scaled Tags Per Million
Pig:118.9 nTPM
Mouse:128.2 nTPM
Allen mouse:10.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 879.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 864.1
2586 Male, age 75, left hemisphere 916.5
2666 Male, age 74, left hemisphere 898.3
1870 Female, age 42, unknown 894.2
1830 Male, age 51, unknown 865.4
2411 Female, age 72, unknown 865.1
1833 Male, age 53, unknown 856.6
2828 Female, age 72, unknown 854.3
2219 Male, age 76, both hemispheres 836.1
1827 Male, age 72, unknown 834.6
2019 Male, age 18, unknown 819.8
Dorsal raphe nucleus
nTPM: 852.3
2750 Male, age 76, both hemispheres 874.5
2047 Male, age 72, unknown 859.3
1828 Male, age 53, unknown 848.8
2016 Female, age 72, unknown 846.5
2298 Female, age 72, unknown 832.2
Inferior colliculus
nTPM: 853.9
2849 Male, age 72, unknown 878.2
1848 Female, age 42, unknown 860.2
1890 Male, age 53, unknown 859.2
2097 Female, age 72, unknown 817.9
Median raphe nucleus
nTPM: 875.8
2220 Male, age 76, midline 875.8
Pedunculopontine tegmental nucleus
nTPM: 876.4
2338 Male, age 61, both hemispheres 911.7
2334 Male, age 80, both hemispheres 897.6
1921 Female, age 85, both hemispheres 819.8
Periaquaductal grey, anterior
nTPM: 873.7
2502 Female, age 75, unknown 899.5
1947 Male, age 18, unknown 867.1
1795 Male, age 51, unknown 854.5
Periaquaductal grey, dorsal
nTPM: 846.1
2850 Male, age 76, both hemispheres 863.0
1840 Male, age 53, unknown 854.0
1831 Male, age 72, unknown 834.5
2464 Female, age 72, unknown 832.9
Periaquaductal grey, lateral
nTPM: 843.1
2053 Male, age 18, unknown 867.9
2272 Male, age 74, both hemispheres 832.8
2140 Male, age 76, both hemispheres 828.6
Pretectal area
nTPM: 830.2
2825 Male, age 18, unknown 853.5
2407 Male, age 75, both hemispheres 851.1
1817 Female, age 42, unknown 844.2
2007 Male, age 72, unknown 842.9
1815 Male, age 53, unknown 835.3
2224 Female, age 72, unknown 833.9
2316 Male, age 76, right hemisphere 828.2
1944 Female, age 72, unknown 820.8
1816 Male, age 51, unknown 812.2
2667 Female, age 75, unknown 809.7
2273 Male, age 74, both hemispheres 800.8
Red nucleus
nTPM: 877.3
2503 Female, age 72, unknown 932.7
2584 Male, age 75, left hemisphere 895.5
1865 Male, age 51, unknown 894.2
2227 Male, age 72, unknown 890.0
2769 Male, age 72, unknown 889.9
1904 Male, age 53, unknown 886.3
2725 Female, age 75, unknown 872.7
1821 Female, age 72, unknown 869.4
2588 Male, age 74, left hemisphere 858.4
2785 Male, age 18, unknown 856.9
1954 Female, age 42, unknown 854.5
2823 Male, age 76, right hemisphere 827.8
Substantia nigra
nTPM: 877.5
2699 Male, age 18, unknown 957.0
1851 Male, age 51, unknown 921.4
2665 Male, age 74, both hemispheres 898.7
1916 Female, age 42, unknown 885.7
2590 Female, age 75, unknown 877.4
2409 Female, age 72, unknown 870.2
2583 Male, age 75, right hemisphere 863.3
1889 Female, age 72, unknown 853.3
1941 Male, age 53, unknown 842.2
2241 Male, age 72, unknown 806.2
Superior colliculus
nTPM: 858.2
1995 Male, age 72, unknown 904.0
1913 Female, age 42, unknown 893.1
2587 Male, age 74, left hemisphere 886.6
1796 Male, age 53, unknown 877.0
2664 Male, age 75, both hemispheres 864.9
2668 Female, age 75, unknown 856.4
1839 Male, age 51, unknown 851.1
1895 Male, age 76, right hemisphere 829.1
2261 Male, age 18, unknown 814.1
2087 Female, age 72, unknown 806.1
Ventral tegmental area
nTPM: 879.5
2223 Female, age 72, unknown 911.1
2410 Female, age 72, unknown 896.0
1915 Female, age 42, unknown 878.0
2021 Male, age 53, unknown 865.8
2218 Male, age 76, both hemispheres 864.2
1942 Male, age 51, unknown 862.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1296.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1296.0
Samples: 139

Max nTPM: 4516.1
Min nTPM: 408.1
Std nTPM: 567.1
Median nTPM: 1225.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4516.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3182.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3084.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3040.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2444.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2321.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2314.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2196.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2185.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2154.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2134.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2132.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2005.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1942.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1929.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1916.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1905.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1805.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1782.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1749.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1749.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1739.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1734.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1716.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1660.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1614.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1603.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1580.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1568.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1562.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1561.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1542.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1536.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1519.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1513.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1462.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1458.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1458.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1453.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1431.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1429.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1425.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1405.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1394.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1386.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1383.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1377.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1377.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1366.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1361.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1360.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1348.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1344.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1343.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1342.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1338.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1330.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1322.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1303.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1302.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1289.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1289.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1289.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1266.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1265.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1254.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1243.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1242.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1228.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1225.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1216.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1205.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1196.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1175.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1171.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1159.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1145.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1105.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1091.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1075.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1065.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1049.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1049.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1040.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1026.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1020.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1019.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1018.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1013.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1011.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1007.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 995.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 979.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 955.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 946.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 945.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 939.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 932.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 930.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 922.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 920.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 919.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 917.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 917.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 910.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 896.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 892.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 889.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 882.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 877.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 874.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 852.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 849.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 842.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 841.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 832.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 828.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 823.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 822.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 806.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 801.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 784.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 782.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 778.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 776.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 775.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 758.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 758.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 749.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 740.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 737.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 735.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 734.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 706.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 653.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 563.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 547.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 493.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 408.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 506.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 506.9
FF:10158-103A5 76 years, female 506.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.9
Pig sample Sample description nTPM
Midbrain
nTPM: 117.4
Samples: 4

Max nTPM: 177.4
Min nTPM: 88.0
Sample A Female 177.4
Sample B Female 107.7
Sample C Male 96.4
Sample D Male 88.0
Periaqueductal gray
nTPM: 98.3
Samples: 3

Max nTPM: 112.1
Min nTPM: 90.2
Sample B Female 92.6
Sample C Male 112.1
Sample D Male 90.2
Substantia nigra
nTPM: 110.6
Samples: 4

Max nTPM: 143.2
Min nTPM: 92.5
Sample A Female 143.2
Sample B Female 107.6
Sample C Male 92.5
Sample D Male 99.1
Superior colliculi
nTPM: 118.9
Samples: 4

Max nTPM: 146.4
Min nTPM: 103.8
Sample A Female 146.4
Sample B Female 103.8
Sample C Male 109.3
Sample D Male 116.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 128.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.2
Samples: 4

Max nTPM: 147.2
Min nTPM: 116.2
Sample A Male 147.2
Sample B Male 116.3
Sample C Female 116.2
Sample D Female 133.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.6
69173436 Antisense, RP_050329_01_E12, Mouse strain C57BL/6J (56 days, male) 10.6

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