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CD81
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  • CD81
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:640.8 nTPM
HPA:640.8 nTPM
GTEx:738.0 nTPM
FANTOM5:767.0 Scaled Tags Per Million
Pig:555.6 nTPM
Mouse:616.2 nTPM
Allen mouse:12.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 640.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 571.7
2586 Male, age 75, left hemisphere 657.1
2828 Female, age 72, unknown 655.7
2411 Female, age 72, unknown 577.7
2666 Male, age 74, left hemisphere 572.1
1870 Female, age 42, unknown 570.7
1827 Male, age 72, unknown 565.0
1833 Male, age 53, unknown 550.0
2019 Male, age 18, unknown 548.8
1830 Male, age 51, unknown 537.2
2219 Male, age 76, both hemispheres 482.7
Dorsal raphe nucleus
nTPM: 632.7
2298 Female, age 72, unknown 707.0
2016 Female, age 72, unknown 680.2
1828 Male, age 53, unknown 603.5
2047 Male, age 72, unknown 594.7
2750 Male, age 76, both hemispheres 578.1
Inferior colliculus
nTPM: 567.1
2097 Female, age 72, unknown 601.4
1890 Male, age 53, unknown 569.5
1848 Female, age 42, unknown 563.6
2849 Male, age 72, unknown 533.9
Median raphe nucleus
nTPM: 518.1
2220 Male, age 76, midline 518.1
Pedunculopontine tegmental nucleus
nTPM: 539.3
1921 Female, age 85, both hemispheres 548.0
2334 Male, age 80, both hemispheres 547.2
2338 Male, age 61, both hemispheres 522.8
Periaquaductal grey, anterior
nTPM: 628.0
1795 Male, age 51, unknown 655.3
1947 Male, age 18, unknown 628.6
2502 Female, age 75, unknown 600.1
Periaquaductal grey, dorsal
nTPM: 613.7
2850 Male, age 76, both hemispheres 635.1
1840 Male, age 53, unknown 632.8
2464 Female, age 72, unknown 603.1
1831 Male, age 72, unknown 583.8
Periaquaductal grey, lateral
nTPM: 640.8
2140 Male, age 76, both hemispheres 668.4
2053 Male, age 18, unknown 630.9
2272 Male, age 74, both hemispheres 623.2
Pretectal area
nTPM: 595.6
2273 Male, age 74, both hemispheres 673.6
2316 Male, age 76, right hemisphere 619.0
2224 Female, age 72, unknown 615.2
2825 Male, age 18, unknown 601.1
2667 Female, age 75, unknown 599.0
1817 Female, age 42, unknown 595.9
1815 Male, age 53, unknown 588.9
1944 Female, age 72, unknown 584.8
2007 Male, age 72, unknown 567.0
1816 Male, age 51, unknown 566.3
2407 Male, age 75, both hemispheres 540.5
Red nucleus
nTPM: 584.2
2503 Female, age 72, unknown 637.7
2227 Male, age 72, unknown 624.4
2769 Male, age 72, unknown 619.1
1954 Female, age 42, unknown 598.9
1821 Female, age 72, unknown 591.4
1904 Male, age 53, unknown 590.1
1865 Male, age 51, unknown 585.7
2725 Female, age 75, unknown 585.5
2785 Male, age 18, unknown 570.1
2823 Male, age 76, right hemisphere 557.9
2588 Male, age 74, left hemisphere 542.9
2584 Male, age 75, left hemisphere 506.7
Substantia nigra
nTPM: 571.0
1851 Male, age 51, unknown 605.3
2590 Female, age 75, unknown 598.6
1916 Female, age 42, unknown 595.2
2699 Male, age 18, unknown 586.9
2583 Male, age 75, right hemisphere 572.4
2665 Male, age 74, both hemispheres 570.8
1889 Female, age 72, unknown 568.3
2241 Male, age 72, unknown 543.7
2409 Female, age 72, unknown 534.7
1941 Male, age 53, unknown 534.4
Superior colliculus
nTPM: 590.7
1995 Male, age 72, unknown 679.9
1796 Male, age 53, unknown 617.5
2087 Female, age 72, unknown 606.3
2261 Male, age 18, unknown 603.3
2664 Male, age 75, both hemispheres 592.1
1913 Female, age 42, unknown 591.1
2668 Female, age 75, unknown 575.2
2587 Male, age 74, left hemisphere 575.1
1839 Male, age 51, unknown 559.4
1895 Male, age 76, right hemisphere 507.4
Ventral tegmental area
nTPM: 591.6
2021 Male, age 53, unknown 621.7
1942 Male, age 51, unknown 621.3
2410 Female, age 72, unknown 608.4
1915 Female, age 42, unknown 595.2
2218 Male, age 76, both hemispheres 557.1
2223 Female, age 72, unknown 546.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 738.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 738.0
Samples: 139

Max nTPM: 1803.2
Min nTPM: 266.4
Std nTPM: 286.9
Median nTPM: 683.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1803.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1769.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1691.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1685.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1571.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1539.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1404.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1225.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1146.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1112.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1102.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1096.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1092.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1083.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1078.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1074.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1016.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 994.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 980.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 978.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 968.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 960.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 956.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 937.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 932.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 927.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 925.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 925.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 908.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 889.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 880.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 878.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 858.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 848.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 847.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 846.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 844.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 843.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 842.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 831.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 830.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 818.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 810.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 802.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 802.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 783.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 779.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 778.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 775.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 763.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 760.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 757.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 756.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 747.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 741.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 740.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 737.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 737.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 734.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 724.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 717.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 701.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 698.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 698.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 696.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 696.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 693.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 691.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 691.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 683.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 673.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 671.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 669.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 667.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 656.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 652.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 647.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 645.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 642.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 639.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 637.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 636.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 632.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 629.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 623.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 622.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 613.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 611.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 609.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 601.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 599.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 593.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 593.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 589.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 584.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 584.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 583.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 579.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 579.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 578.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 577.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 572.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 567.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 566.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 560.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 559.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 549.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 548.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 538.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 535.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 529.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 528.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 527.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 523.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 510.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 508.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 507.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 504.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 498.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 493.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 489.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 478.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 476.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 474.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 469.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 463.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 461.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 431.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 411.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 401.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 397.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 385.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 373.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 344.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 330.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 328.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 310.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 287.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 266.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 767.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 767.0
FF:10158-103A5 76 years, female 767.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 555.6
Pig sample Sample description nTPM
Midbrain
nTPM: 500.1
Samples: 4

Max nTPM: 859.4
Min nTPM: 340.3
Sample A Female 859.4
Sample B Female 421.2
Sample C Male 379.5
Sample D Male 340.3
Periaqueductal gray
nTPM: 460.8
Samples: 3

Max nTPM: 539.5
Min nTPM: 409.6
Sample B Female 433.3
Sample C Male 539.5
Sample D Male 409.6
Substantia nigra
nTPM: 555.6
Samples: 4

Max nTPM: 634.5
Min nTPM: 443.0
Sample A Female 634.5
Sample B Female 443.0
Sample C Male 525.4
Sample D Male 619.4
Superior colliculi
nTPM: 417.6
Samples: 4

Max nTPM: 547.1
Min nTPM: 291.4
Sample A Female 547.1
Sample B Female 291.4
Sample C Male 385.7
Sample D Male 446.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 616.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 616.2
Samples: 4

Max nTPM: 636.2
Min nTPM: 578.8
Sample A Male 628.4
Sample B Male 578.8
Sample C Female 621.4
Sample D Female 636.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.1
227 Antisense, RP_Baylor_102672, Mouse strain C57BL/6J (56 days, male) 12.1
68269526 Antisense, RP_041129_01_G04, Mouse strain C57BL/6J (56 days, male) 12.1
226 Antisense, RP_Baylor_102672, Mouse strain C57BL/6J (56 days, male) 9.0

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