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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:367.9 nTPM
HPA:367.9 nTPM
GTEx:195.3 nTPM
FANTOM5:1414.9 Scaled Tags Per Million
Pig:468.0 nTPM
Mouse:178.9 nTPM
Allen mouse:10.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 367.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 266.9
1870 Female, age 42, unknown 382.9
1830 Male, age 51, unknown 370.9
1833 Male, age 53, unknown 359.5
2411 Female, age 72, unknown 307.6
2019 Male, age 18, unknown 288.1
2828 Female, age 72, unknown 250.1
1827 Male, age 72, unknown 195.6
2666 Male, age 74, left hemisphere 189.7
2219 Male, age 76, both hemispheres 175.8
2586 Male, age 75, left hemisphere 148.6
Dorsal raphe nucleus
nTPM: 206.9
2750 Male, age 76, both hemispheres 326.1
2016 Female, age 72, unknown 259.8
1828 Male, age 53, unknown 212.1
2047 Male, age 72, unknown 124.8
2298 Female, age 72, unknown 111.8
Inferior colliculus
nTPM: 209.9
1848 Female, age 42, unknown 228.0
2849 Male, age 72, unknown 222.9
1890 Male, age 53, unknown 211.0
2097 Female, age 72, unknown 177.6
Median raphe nucleus
nTPM: 200.3
2220 Male, age 76, midline 200.3
Pedunculopontine tegmental nucleus
nTPM: 275.8
2338 Male, age 61, both hemispheres 337.3
2334 Male, age 80, both hemispheres 275.2
1921 Female, age 85, both hemispheres 215.0
Periaquaductal grey, anterior
nTPM: 136.9
2502 Female, age 75, unknown 155.9
1947 Male, age 18, unknown 152.3
1795 Male, age 51, unknown 102.5
Periaquaductal grey, dorsal
nTPM: 186.2
2850 Male, age 76, both hemispheres 260.6
2464 Female, age 72, unknown 205.5
1831 Male, age 72, unknown 164.5
1840 Male, age 53, unknown 114.2
Periaquaductal grey, lateral
nTPM: 187.4
2140 Male, age 76, both hemispheres 214.8
2053 Male, age 18, unknown 184.5
2272 Male, age 74, both hemispheres 162.8
Pretectal area
nTPM: 185.3
2316 Male, age 76, right hemisphere 266.5
1815 Male, age 53, unknown 248.6
2667 Female, age 75, unknown 231.2
1817 Female, age 42, unknown 199.2
2825 Male, age 18, unknown 192.8
2407 Male, age 75, both hemispheres 189.1
2273 Male, age 74, both hemispheres 174.3
2224 Female, age 72, unknown 173.2
2007 Male, age 72, unknown 145.5
1944 Female, age 72, unknown 130.1
1816 Male, age 51, unknown 88.3
Red nucleus
nTPM: 367.9
1865 Male, age 51, unknown 468.2
1904 Male, age 53, unknown 452.6
1954 Female, age 42, unknown 433.2
1821 Female, age 72, unknown 427.5
2823 Male, age 76, right hemisphere 411.8
2227 Male, age 72, unknown 410.7
2503 Female, age 72, unknown 402.5
2769 Male, age 72, unknown 401.3
2785 Male, age 18, unknown 337.1
2725 Female, age 75, unknown 260.0
2588 Male, age 74, left hemisphere 243.5
2584 Male, age 75, left hemisphere 166.0
Substantia nigra
nTPM: 210.1
2699 Male, age 18, unknown 309.3
2409 Female, age 72, unknown 265.0
2583 Male, age 75, right hemisphere 231.3
1851 Male, age 51, unknown 225.1
1889 Female, age 72, unknown 219.5
2241 Male, age 72, unknown 202.7
2590 Female, age 75, unknown 201.3
1941 Male, age 53, unknown 162.6
1916 Female, age 42, unknown 152.3
2665 Male, age 74, both hemispheres 131.3
Superior colliculus
nTPM: 230.0
1913 Female, age 42, unknown 388.6
1995 Male, age 72, unknown 384.8
1895 Male, age 76, right hemisphere 279.8
1839 Male, age 51, unknown 243.8
2587 Male, age 74, left hemisphere 238.9
2668 Female, age 75, unknown 219.2
1796 Male, age 53, unknown 161.6
2087 Female, age 72, unknown 149.7
2664 Male, age 75, both hemispheres 127.6
2261 Male, age 18, unknown 105.8
Ventral tegmental area
nTPM: 230.0
2223 Female, age 72, unknown 334.0
2410 Female, age 72, unknown 245.2
2218 Male, age 76, both hemispheres 216.0
1942 Male, age 51, unknown 200.2
2021 Male, age 53, unknown 195.8
1915 Female, age 42, unknown 188.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 195.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 195.3
Samples: 139

Max nTPM: 370.8
Min nTPM: 54.9
Std nTPM: 63.8
Median nTPM: 183.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 370.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 369.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 342.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 325.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 325.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 324.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 321.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 319.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 316.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 310.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 310.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 304.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 296.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 295.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 293.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 291.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 287.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 281.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 277.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 276.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 264.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 263.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 254.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 250.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 250.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 249.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 246.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 246.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 243.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 242.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 242.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 239.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 238.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 237.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 237.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 236.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 236.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 232.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 232.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 227.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 221.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 219.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 216.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 214.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 214.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 211.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 211.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 207.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 203.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 203.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 203.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 202.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 202.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 200.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 199.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 198.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 197.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 194.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 194.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 193.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 193.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 193.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 192.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 189.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 187.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 186.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 186.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 183.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 183.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 183.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 182.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 182.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 181.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 180.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 180.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 179.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 179.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 178.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 177.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 177.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 174.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 173.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 173.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 173.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 172.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 171.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 169.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 168.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 166.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 166.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 166.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 165.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 164.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 162.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 162.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 160.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 159.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 158.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 158.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 155.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 154.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 154.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 154.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 153.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 152.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 150.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 147.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 147.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 146.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 143.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 143.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 143.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 142.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 142.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 140.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 136.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 135.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 134.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 132.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 126.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 122.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 121.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 121.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 121.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 119.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 115.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 113.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 113.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 111.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 107.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 106.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 101.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 100.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 99.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 98.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 77.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 54.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1414.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1414.9
FF:10158-103A5 76 years, female 1414.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 468.0
Pig sample Sample description nTPM
Midbrain
nTPM: 468.1
Samples: 4

Max nTPM: 755.1
Min nTPM: 301.8
Sample A Female 755.1
Sample B Female 495.8
Sample C Male 319.5
Sample D Male 301.8
Periaqueductal gray
nTPM: 378.2
Samples: 3

Max nTPM: 429.6
Min nTPM: 323.7
Sample B Female 429.6
Sample C Male 323.7
Sample D Male 381.2
Substantia nigra
nTPM: 432.4
Samples: 4

Max nTPM: 582.5
Min nTPM: 334.6
Sample A Female 430.5
Sample B Female 334.6
Sample C Male 381.9
Sample D Male 582.5
Superior colliculi
nTPM: 332.8
Samples: 4

Max nTPM: 401.9
Min nTPM: 194.3
Sample A Female 371.3
Sample B Female 194.3
Sample C Male 363.5
Sample D Male 401.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 178.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 178.9
Samples: 4

Max nTPM: 188.3
Min nTPM: 168.5
Sample A Male 168.5
Sample B Male 178.0
Sample C Female 188.3
Sample D Female 180.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.4
1151 Antisense, RP_Baylor_102604, Mouse strain C57BL/6J (56 days, male) 15.5
68797858 Antisense, RP_050215_01_C08, Mouse strain C57BL/6J (56 days, male) 13.3
73635471 Antisense, RP_051130_02_F07, Mouse strain C57BL/6J (56 days, male) 2.4

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