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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:1224.8 nTPM
HPA:1224.8 nTPM
FANTOM5:2580.5 Scaled Tags Per Million
Pig:737.8 nTPM
Allen mouse:8.2 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 1224.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 695.1
2301 Female, age 85, both hemispheres 1181.9
2090 Male, age 80, both hemispheres 606.3
2188 Female, age 91, both hemispheres 538.4
1984 Male, age 76, both hemispheres 453.7
Dorsal cochlear nucleus
nTPM: 694.7
2187 Female, age 91, both hemispheres 966.8
2802 Male, age 74, right hemisphere 728.3
2370 Male, age 61, both hemispheres 694.8
2378 Male, age 80, both hemispheres 577.9
2058 Male, age 76, both hemispheres 505.7
Dorsal tegmental nucleus
nTPM: 1020.6
2083 Male, age 80, both hemispheres 1114.2
1936 Male, age 76, left hemisphere 1047.2
2326 Male, age 74, both hemispheres 982.1
2358 Male, age 61, both hemispheres 939.0
Dorsolateral tegmental area
nTPM: 880.7
2360 Male, age 74, both hemispheres 970.8
2654 Male, age 80, both hemispheres 967.0
2141 Male, age 76, both hemispheres 950.9
2751 Female, age 85, both hemispheres 768.6
2337 Male, age 61, both hemispheres 746.3
Kolliker-Fuse nucleus
nTPM: 1060.2
2315 Male, age 76, right hemisphere 1866.3
2163 Male, age 80, both hemispheres 836.9
2793 Female, age 91, left hemisphere 477.5
Lateral lemniscal nuclei
nTPM: 424.6
2746 Female, age 85, left hemisphere 578.5
2169 Male, age 76, both hemispheres 461.9
2320 Female, age 91, left hemisphere 383.3
2036 Male, age 80, both hemispheres 359.7
2453 Male, age 74, right hemisphere 339.6
Lateral parabrachial nucleus
nTPM: 868.3
2792 Male, age 76, both hemispheres 1169.5
2139 Female, age 85, right hemisphere 836.7
2013 Male, age 80, both hemispheres 764.8
2790 Male, age 61, both hemispheres 702.2
Lateral vestibular nucleus
nTPM: 956.2
2311 Male, age 80, both hemispheres 1126.3
2184 Male, age 76, both hemispheres 786.0
Locus coeruleus
nTPM: 912.8
2317 Female, age 72, unknown 1069.1
2123 Female, age 91, both hemispheres 1003.1
2162 Male, age 80, both hemispheres 985.0
1980 Male, age 76, both hemispheres 959.1
2720 Male, age 74, both hemispheres 880.2
2014 Male, age 55, unknown 763.0
2788 Male, age 74, unknown 729.9
Medial olivary nucleus
nTPM: 1090.9
2138 Female, age 91, both hemispheres 1312.5
1943 Male, age 61, both hemispheres 1241.7
2851 Male, age 80, both hemispheres 928.4
1962 Male, age 76, both hemispheres 880.9
Medial parabrachial nucleus
nTPM: 857.5
2170 Female, age 91, both hemispheres 929.8
2156 Male, age 61, both hemispheres 929.3
2786 Male, age 76, both hemispheres 889.1
2854 Male, age 80, both hemispheres 808.4
2463 Female, age 85, right hemisphere 731.0
Medial periolivary nuclei
nTPM: 520.1
2791 Male, age 74, right hemisphere 628.7
2063 Male, age 76, both hemispheres 536.4
2458 Female, age 91, both hemispheres 504.2
2081 Male, age 80, both hemispheres 474.5
2171 Female, age 85, both hemispheres 456.8
Motor facial nucleus
nTPM: 606.9
2126 Male, age 61, both hemispheres 741.7
2795 Female, age 91, both hemispheres 690.4
2697 Female, age 85, both hemispheres 633.6
2365 Male, age 74, right hemisphere 581.7
2062 Male, age 76, both hemispheres 573.4
2327 Male, age 80, both hemispheres 420.6
Motor trigeminal nucleus
nTPM: 597.3
2309 Male, age 76, both hemispheres 778.5
2335 Male, age 61, both hemispheres 777.2
2321 Female, age 91, both hemispheres 583.1
2560 Male, age 74, both hemispheres 454.6
2079 Male, age 80, both hemispheres 393.0
Nuclei of the trapezoid body
nTPM: 577.4
2368 Female, age 91, both hemispheres 644.5
1983 Male, age 76, both hemispheres 637.4
2166 Male, age 80, both hemispheres 566.9
2159 Male, age 61, both hemispheres 560.7
2735 Female, age 85, both hemispheres 477.8
Paramedian reticular nucleus
nTPM: 702.6
2057 Male, age 80, both hemispheres 848.4
2313 Male, age 61, both hemispheres 713.0
2052 Male, age 76, both hemispheres 639.7
2050 Female, age 85, both hemispheres 609.2
Pontine nuclei
nTPM: 445.1
2115 Male, age 80, left hemisphere 554.8
2109 Female, age 72, unknown 484.9
1968 Male, age 76, left hemisphere 455.7
1863 Male, age 55, unknown 430.4
2787 Female, age 85, both hemispheres 425.6
2319 Female, age 91, both hemispheres 420.9
2727 Male, age 61, right hemisphere 417.1
2454 Male, age 74, left hemisphere 371.8
Pontine raphe nucleus
nTPM: 797.1
2853 Male, age 76, midline 1051.0
2122 Female, age 85, midline 543.2
Posteroventral cochlear nucleus
nTPM: 651.2
2752 Female, age 85, both hemispheres 842.2
2371 Male, age 61, both hemispheres 771.0
2070 Male, age 76, both hemispheres 590.7
2341 Male, age 80, both hemispheres 563.1
2135 Female, age 91, both hemispheres 489.1
Principal sensory trigeminal nucleus
nTPM: 620.3
2324 Male, age 76, both hemispheres 996.6
2158 Male, age 61, both hemispheres 626.7
2008 Male, age 80, left hemisphere 453.6
2367 Female, age 91, left hemisphere 404.3
Reticular pontine nucleus, caudal
nTPM: 481.2
2092 Male, age 76, both hemispheres 643.0
2559 Male, age 74, both hemispheres 473.3
2457 Female, age 91, both hemispheres 423.7
2332 Male, age 80, right hemisphere 384.8
Reticular pontine nucleus, oral
nTPM: 651.8
1939 Male, age 80, both hemispheres 937.7
2167 Male, age 76, both hemispheres 889.7
2012 Female, age 85, both hemispheres 591.6
2366 Female, age 91, both hemispheres 433.9
2361 Male, age 74, both hemispheres 406.2
Reticulotegmental nucleus
nTPM: 709.0
2322 Female, age 91, both hemispheres 816.4
2333 Male, age 80, both hemispheres 755.1
2325 Male, age 76, both hemispheres 713.7
2452 Male, age 74, both hemispheres 550.9
Spinal trigeminal nucleus, oral
nTPM: 582.9
2737 Female, age 85, both hemispheres 659.2
2164 Male, age 80, both hemispheres 615.5
1978 Male, age 76, both hemispheres 474.0
Subcoeruleus area
nTPM: 770.1
2323 Female, age 91, left hemisphere 906.4
2451 Male, age 74, both hemispheres 852.2
1958 Male, age 80, both hemispheres 775.2
2369 Female, age 85, left hemisphere 770.7
2089 Male, age 76, left hemisphere 546.1
Superior olive
nTPM: 533.2
2364 Male, age 74, right hemisphere 666.1
2561 Female, age 91, both hemispheres 530.9
2020 Male, age 76, both hemispheres 500.2
2329 Male, age 80, right hemisphere 496.6
1875 Female, age 85, both hemispheres 472.3
Superior vestibular nucleus
nTPM: 1224.8
2061 Male, age 76, both hemispheres 1404.6
2383 Male, age 74, both hemispheres 1304.6
2015 Male, age 80, both hemispheres 965.1
Ventral periolivary nuclei
nTPM: 517.6
2130 Female, age 85, both hemispheres 596.6
2165 Male, age 80, both hemispheres 563.2
2023 Male, age 76, both hemispheres 473.1
2794 Female, age 91, left hemisphere 437.5
Ventrolateral tegmental area, A5 NE cell group
nTPM: 628.9
2359 Male, age 61, both hemispheres 884.4
2840 Female, age 85, both hemispheres 710.4
2456 Female, age 91, both hemispheres 591.1
1959 Male, age 76, both hemispheres 563.3
2161 Male, age 80, both hemispheres 546.1
2449 Male, age 74, both hemispheres 478.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 2580.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 2580.5
FF:10165-103B3 76 years, female 2912.2
FF:10182-103D2 60 years, female 2248.8
Pons
Scaled Tags Per Million: 1440.1
FF:10033-101E6 18-54 years, mixed 1440.1

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 737.8
Pig sample Sample description nTPM
Pons
nTPM: 737.8
Samples: 4

Max nTPM: 885.8
Min nTPM: 567.9
Sample A Female 732.4
Sample B Female 567.9
Sample C Male 765.2
Sample D Male 885.8

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 8.2
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 8.2
73788443 Antisense, RP_051213_01_B02, Mouse strain C57BL/6J (56 days, male) 9.7
73512200 Antisense, RP_050712_04_F12, Mouse strain C57BL/6J (56 days, male) 7.9
70429441 Antisense, RP_050614_01_F09, Mouse strain C57BL/6J (56 days, male) 7.1
70918880 Antisense, RP_050712_04_F12, Mouse strain C57BL/6J (56 days, male) 3.3

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.