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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1168.8 nTPM
HPA:1168.8 nTPM
GTEx:1020.9 nTPM
FANTOM5:101.8 Scaled Tags Per Million
Pig:317.1 nTPM
Mouse:616.0 nTPM
Allen mouse:12.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1168.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1155.1
1870 Female, age 42, unknown 1172.0
2411 Female, age 72, unknown 1165.0
1827 Male, age 72, unknown 1164.3
2666 Male, age 74, left hemisphere 1163.0
2828 Female, age 72, unknown 1157.4
1833 Male, age 53, unknown 1153.6
2019 Male, age 18, unknown 1148.0
1830 Male, age 51, unknown 1147.4
2586 Male, age 75, left hemisphere 1142.6
2219 Male, age 76, both hemispheres 1137.1
Dorsal raphe nucleus
nTPM: 1154.9
2298 Female, age 72, unknown 1167.5
2750 Male, age 76, both hemispheres 1156.1
1828 Male, age 53, unknown 1154.6
2016 Female, age 72, unknown 1152.0
2047 Male, age 72, unknown 1144.1
Inferior colliculus
nTPM: 1165.9
2849 Male, age 72, unknown 1174.8
1890 Male, age 53, unknown 1170.4
2097 Female, age 72, unknown 1161.2
1848 Female, age 42, unknown 1157.1
Median raphe nucleus
nTPM: 1152.0
2220 Male, age 76, midline 1152.0
Pedunculopontine tegmental nucleus
nTPM: 1168.8
2334 Male, age 80, both hemispheres 1182.8
2338 Male, age 61, both hemispheres 1172.3
1921 Female, age 85, both hemispheres 1151.4
Periaquaductal grey, anterior
nTPM: 1153.6
2502 Female, age 75, unknown 1171.3
1795 Male, age 51, unknown 1145.9
1947 Male, age 18, unknown 1143.6
Periaquaductal grey, dorsal
nTPM: 1155.9
1840 Male, age 53, unknown 1177.8
1831 Male, age 72, unknown 1155.2
2850 Male, age 76, both hemispheres 1153.7
2464 Female, age 72, unknown 1136.8
Periaquaductal grey, lateral
nTPM: 1141.8
2053 Male, age 18, unknown 1163.3
2140 Male, age 76, both hemispheres 1139.7
2272 Male, age 74, both hemispheres 1122.3
Pretectal area
nTPM: 1150.1
1817 Female, age 42, unknown 1156.0
2825 Male, age 18, unknown 1155.5
1815 Male, age 53, unknown 1155.4
2224 Female, age 72, unknown 1154.2
2407 Male, age 75, both hemispheres 1152.3
1816 Male, age 51, unknown 1151.5
1944 Female, age 72, unknown 1151.3
2007 Male, age 72, unknown 1150.4
2316 Male, age 76, right hemisphere 1150.3
2667 Female, age 75, unknown 1144.4
2273 Male, age 74, both hemispheres 1130.1
Red nucleus
nTPM: 1160.3
1821 Female, age 72, unknown 1181.3
2725 Female, age 75, unknown 1181.1
2503 Female, age 72, unknown 1174.6
2584 Male, age 75, left hemisphere 1167.7
1865 Male, age 51, unknown 1165.1
2769 Male, age 72, unknown 1159.5
2588 Male, age 74, left hemisphere 1156.7
1904 Male, age 53, unknown 1152.7
2227 Male, age 72, unknown 1149.9
1954 Female, age 42, unknown 1148.2
2785 Male, age 18, unknown 1144.2
2823 Male, age 76, right hemisphere 1142.9
Substantia nigra
nTPM: 1167.2
2665 Male, age 74, both hemispheres 1193.8
2699 Male, age 18, unknown 1189.1
2409 Female, age 72, unknown 1184.2
1851 Male, age 51, unknown 1182.9
2241 Male, age 72, unknown 1168.6
1889 Female, age 72, unknown 1167.3
1916 Female, age 42, unknown 1162.8
1941 Male, age 53, unknown 1148.4
2590 Female, age 75, unknown 1138.9
2583 Male, age 75, right hemisphere 1136.4
Superior colliculus
nTPM: 1158.2
2587 Male, age 74, left hemisphere 1197.8
1895 Male, age 76, right hemisphere 1169.0
1913 Female, age 42, unknown 1160.6
1839 Male, age 51, unknown 1159.0
1995 Male, age 72, unknown 1157.9
1796 Male, age 53, unknown 1155.1
2668 Female, age 75, unknown 1154.2
2664 Male, age 75, both hemispheres 1145.8
2261 Male, age 18, unknown 1141.8
2087 Female, age 72, unknown 1140.8
Ventral tegmental area
nTPM: 1157.1
1915 Female, age 42, unknown 1182.8
2223 Female, age 72, unknown 1157.3
2410 Female, age 72, unknown 1155.5
2021 Male, age 53, unknown 1153.5
1942 Male, age 51, unknown 1148.5
2218 Male, age 76, both hemispheres 1145.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1020.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1020.9
Samples: 139

Max nTPM: 3642.6
Min nTPM: 434.7
Std nTPM: 424.9
Median nTPM: 930.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3642.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2448.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2427.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2202.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2134.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2098.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2011.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1657.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1633.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1616.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1517.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1496.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1480.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1439.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1424.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1372.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1346.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1340.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1319.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1305.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1288.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1285.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1263.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1233.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1230.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1227.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1224.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1223.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1192.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1180.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1176.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1172.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1168.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1159.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1151.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1150.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1148.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1146.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1142.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1141.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1136.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1135.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1120.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1116.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1080.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1072.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1072.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1064.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1059.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1042.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1041.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1031.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1026.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1011.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1008.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1006.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 999.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 999.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 994.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 988.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 984.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 977.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 975.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 967.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 964.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 962.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 955.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 943.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 930.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 930.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 926.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 908.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 904.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 903.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 894.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 889.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 887.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 886.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 881.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 875.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 856.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 855.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 849.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 849.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 844.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 828.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 821.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 819.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 816.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 815.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 810.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 809.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 796.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 796.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 793.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 791.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 787.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 785.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 784.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 776.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 773.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 771.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 769.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 761.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 754.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 753.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 751.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 746.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 743.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 739.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 739.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 733.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 731.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 716.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 714.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 712.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 711.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 694.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 694.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 692.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 682.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 680.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 679.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 675.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 662.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 662.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 652.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 646.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 642.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 638.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 610.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 602.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 597.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 577.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 569.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 530.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 501.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 492.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 434.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 101.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 101.8
FF:10158-103A5 76 years, female 101.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 317.1
Pig sample Sample description nTPM
Midbrain
nTPM: 304.0
Samples: 4

Max nTPM: 386.8
Min nTPM: 245.9
Sample A Female 386.8
Sample B Female 334.1
Sample C Male 245.9
Sample D Male 249.0
Periaqueductal gray
nTPM: 241.0
Samples: 3

Max nTPM: 253.2
Min nTPM: 232.0
Sample B Female 253.2
Sample C Male 237.8
Sample D Male 232.0
Substantia nigra
nTPM: 295.8
Samples: 4

Max nTPM: 384.7
Min nTPM: 240.2
Sample A Female 384.7
Sample B Female 299.8
Sample C Male 258.4
Sample D Male 240.2
Superior colliculi
nTPM: 317.1
Samples: 4

Max nTPM: 355.3
Min nTPM: 283.5
Sample A Female 355.3
Sample B Female 318.2
Sample C Male 311.4
Sample D Male 283.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 616.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 616.1
Samples: 4

Max nTPM: 654.7
Min nTPM: 575.2
Sample A Male 654.7
Sample B Male 607.2
Sample C Female 575.2
Sample D Female 627.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.9
69262115 Antisense, RP_050224_01_A12, Mouse strain C57BL/6J (56 days, male) 12.9

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