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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:524.8 nTPM
HPA:524.8 nTPM
FANTOM5:1126.1 Scaled Tags Per Million
Pig:549.7 nTPM
Mouse:357.0 nTPM
Allen mouse:14.6 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 524.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 431.5
2188 Female, age 91, both hemispheres 490.5
2301 Female, age 85, both hemispheres 457.1
2090 Male, age 80, both hemispheres 392.6
1984 Male, age 76, both hemispheres 385.7
Area postrema
nTPM: 408.7
2799 Male, age 61, both hemispheres 467.1
2306 Male, age 80, both hemispheres 405.9
2054 Male, age 76, both hemispheres 353.3
Cuneate nuclei
nTPM: 438.2
2376 Male, age 61, both hemispheres 461.8
2131 Male, age 76, both hemispheres 433.4
2381 Male, age 80, both hemispheres 419.3
Dorsal cochlear nucleus
nTPM: 412.4
2187 Female, age 91, both hemispheres 462.2
2802 Male, age 74, right hemisphere 435.5
2378 Male, age 80, both hemispheres 400.5
2370 Male, age 61, both hemispheres 394.5
2058 Male, age 76, both hemispheres 369.5
Dorsal medullary reticular nucleus
nTPM: 425.0
2040 Female, age 85, both hemispheres 502.4
2373 Male, age 61, both hemispheres 403.3
2088 Male, age 76, both hemispheres 369.4
Dorsal motor vagal complex
nTPM: 394.9
2000 Male, age 74, unknown 458.4
2133 Female, age 91, both hemispheres 450.9
2844 Male, age 55, unknown 414.8
2643 Male, age 74, both hemispheres 392.7
2813 Female, age 72, unknown 385.8
2797 Male, age 61, both hemispheres 365.0
2185 Male, age 76, both hemispheres 358.8
2807 Female, age 85, both hemispheres 332.6
Dorsal tegmental nucleus
nTPM: 418.2
2083 Male, age 80, both hemispheres 450.7
2326 Male, age 74, both hemispheres 437.2
2358 Male, age 61, both hemispheres 403.2
1936 Male, age 76, left hemisphere 381.9
Dorsolateral tegmental area
nTPM: 414.1
2751 Female, age 85, both hemispheres 462.9
2654 Male, age 80, both hemispheres 460.5
2337 Male, age 61, both hemispheres 409.8
2360 Male, age 74, both hemispheres 373.5
2141 Male, age 76, both hemispheres 364.0
Gigantocellular reticular nuclei, medullary
nTPM: 452.9
2314 Male, age 61, both hemispheres 493.2
2387 Female, age 91, both hemispheres 484.3
1876 Female, age 85, both hemispheres 452.1
2462 Male, age 74, both hemispheres 442.3
2310 Male, age 80, both hemispheres 441.3
2022 Male, age 76, right hemisphere 404.0
Gigantocellular reticular nuclei, pars
nTPM: 447.6
2168 Male, age 76, both hemispheres 511.5
2336 Male, age 61, both hemispheres 440.2
2084 Female, age 85, both hemispheres 438.5
2706 Male, age 80, both hemispheres 428.9
2330 Male, age 80, both hemispheres 418.7
Inferior olive
nTPM: 449.2
2563 Male, age 74, both hemispheres 487.8
2628 Female, age 91, both hemispheres 460.2
2178 Male, age 61, both hemispheres 451.4
2085 Female, age 85, both hemispheres 446.5
2379 Male, age 80, both hemispheres 400.3
Kolliker-Fuse nucleus
nTPM: 461.1
2793 Female, age 91, left hemisphere 534.0
2163 Male, age 80, both hemispheres 477.6
2315 Male, age 76, right hemisphere 371.7
Lateral lemniscal nuclei
nTPM: 493.0
2169 Male, age 76, both hemispheres 535.3
2036 Male, age 80, both hemispheres 503.2
2320 Female, age 91, left hemisphere 490.1
2746 Female, age 85, left hemisphere 469.6
2453 Male, age 74, right hemisphere 466.8
Lateral medullary reticular nucleus
nTPM: 463.6
2305 Male, age 74, both hemispheres 523.4
2044 Male, age 76, both hemispheres 499.7
2852 Male, age 80, both hemispheres 455.7
2374 Male, age 61, both hemispheres 448.5
2804 Female, age 91, both hemispheres 432.2
2190 Female, age 85, both hemispheres 421.9
Lateral parabrachial nucleus
nTPM: 437.3
2139 Female, age 85, right hemisphere 462.9
2013 Male, age 80, both hemispheres 449.3
2790 Male, age 61, both hemispheres 419.1
2792 Male, age 76, both hemispheres 417.7
Lateral vestibular nucleus
nTPM: 448.7
2184 Male, age 76, both hemispheres 471.4
2311 Male, age 80, both hemispheres 426.0
Locus coeruleus
nTPM: 436.6
2014 Male, age 55, unknown 469.3
2123 Female, age 91, both hemispheres 460.8
2720 Male, age 74, both hemispheres 453.8
2317 Female, age 72, unknown 438.8
1980 Male, age 76, both hemispheres 416.1
2162 Male, age 80, both hemispheres 411.7
2788 Male, age 74, unknown 405.7
Medial olivary nucleus
nTPM: 427.2
1943 Male, age 61, both hemispheres 469.4
2851 Male, age 80, both hemispheres 426.7
1962 Male, age 76, both hemispheres 418.2
2138 Female, age 91, both hemispheres 394.4
Medial parabrachial nucleus
nTPM: 439.1
2170 Female, age 91, both hemispheres 506.8
2854 Male, age 80, both hemispheres 465.8
2156 Male, age 61, both hemispheres 419.4
2463 Female, age 85, right hemisphere 418.5
2786 Male, age 76, both hemispheres 385.1
Medial periolivary nuclei
nTPM: 477.4
2063 Male, age 76, both hemispheres 524.4
2171 Female, age 85, both hemispheres 521.5
2791 Male, age 74, right hemisphere 464.8
2458 Female, age 91, both hemispheres 445.0
2081 Male, age 80, both hemispheres 431.4
Medial vestibular nucleus
nTPM: 480.8
2624 Male, age 61, both hemispheres 518.6
2801 Male, age 74, both hemispheres 515.0
2803 Female, age 91, both hemispheres 493.3
2134 Male, age 76, both hemispheres 462.9
2093 Male, age 80, both hemispheres 455.2
2743 Female, age 85, both hemispheres 439.5
Motor facial nucleus
nTPM: 474.0
2062 Male, age 76, both hemispheres 550.9
2365 Male, age 74, right hemisphere 491.2
2697 Female, age 85, both hemispheres 490.3
2327 Male, age 80, both hemispheres 449.0
2795 Female, age 91, both hemispheres 441.2
2126 Male, age 61, both hemispheres 421.1
Motor hypoglossal nucleus
nTPM: 445.1
2125 Female, age 91, both hemispheres 512.8
2132 Female, age 85, both hemispheres 474.5
2182 Male, age 80, both hemispheres 466.4
2461 Male, age 61, both hemispheres 427.9
2277 Male, age 76, both hemispheres 344.0
Motor trigeminal nucleus
nTPM: 444.7
2560 Male, age 74, both hemispheres 521.7
2321 Female, age 91, both hemispheres 448.9
2079 Male, age 80, both hemispheres 443.5
2335 Male, age 61, both hemispheres 411.9
2309 Male, age 76, both hemispheres 397.4
Nuclei of the trapezoid body
nTPM: 488.0
2159 Male, age 61, both hemispheres 549.6
1983 Male, age 76, both hemispheres 499.1
2735 Female, age 85, both hemispheres 484.2
2368 Female, age 91, both hemispheres 455.0
2166 Male, age 80, both hemispheres 452.2
Nucleus ambiguus
nTPM: 433.5
2096 Female, age 85, both hemispheres 469.5
2071 Male, age 76, both hemispheres 397.4
Nucleus cuneatus
nTPM: 415.0
2564 Male, age 74, both hemispheres 472.2
2380 Male, age 80, both hemispheres 435.5
2100 Male, age 76, both hemispheres 399.1
2562 Male, age 61, both hemispheres 396.7
2808 Female, age 85, both hemispheres 394.4
2805 Female, age 91, both hemispheres 391.8
Nucleus gracilis
nTPM: 428.7
2627 Male, age 74, both hemispheres 467.3
2382 Male, age 80, both hemispheres 446.4
2299 Female, age 85, both hemispheres 372.5
Nucleus raphe magnus
nTPM: 498.6
2160 Male, age 61, both hemispheres 579.7
2172 Female, age 85, both hemispheres 507.4
2455 Male, age 74, both hemispheres 485.0
2328 Male, age 80, both hemispheres 481.1
2051 Male, age 76, both hemispheres 475.7
2459 Female, age 91, both hemispheres 462.9
Nucleus raphe obscurus
nTPM: 454.9
2845 Female, age 85, midline 502.0
2800 Male, age 61, midline 475.1
2142 Male, age 76, midline 387.5
Nucleus raphe pallidus
nTPM: 461.0
1924 Male, age 61, midline 513.3
2183 Male, age 80, midline 479.8
2145 Male, age 76, midline 389.8
Nucleus tractus solitarii
nTPM: 374.6
2144 Female, age 91, right hemisphere 442.2
2656 Male, age 76, both hemispheres 363.6
2307 Male, age 80, both hemispheres 349.7
2191 Female, age 85, both hemispheres 342.9
Paramedian reticular nucleus
nTPM: 477.0
2050 Female, age 85, both hemispheres 535.1
2057 Male, age 80, both hemispheres 476.3
2313 Male, age 61, both hemispheres 448.4
2052 Male, age 76, both hemispheres 448.2
Parvicellular reticular nuclei
nTPM: 472.1
2558 Male, age 74, both hemispheres 501.0
2119 Male, age 80, both hemispheres 459.1
2095 Male, age 76, both hemispheres 456.1
Parvicellular reticular nuclei, medullary
nTPM: 436.0
2189 Female, age 91, both hemispheres 470.1
2091 Female, age 85, both hemispheres 439.3
2181 Male, age 80, left hemisphere 398.5
Peritrigeminal nucleus
nTPM: 462.5
2179 Male, age 61, both hemispheres 483.1
2136 Male, age 76, both hemispheres 459.6
2067 Female, age 85, both hemispheres 445.0
Pontine nuclei
nTPM: 524.8
1863 Male, age 55, unknown 590.5
2727 Male, age 61, right hemisphere 571.0
2109 Female, age 72, unknown 566.2
2454 Male, age 74, left hemisphere 533.7
2787 Female, age 85, both hemispheres 523.2
1968 Male, age 76, left hemisphere 514.0
2319 Female, age 91, both hemispheres 478.4
2115 Male, age 80, left hemisphere 421.9
Pontine raphe nucleus
nTPM: 438.3
2122 Female, age 85, midline 452.1
2853 Male, age 76, midline 424.6
Posteroventral cochlear nucleus
nTPM: 441.3
2135 Female, age 91, both hemispheres 487.5
2341 Male, age 80, both hemispheres 436.0
2752 Female, age 85, both hemispheres 434.9
2371 Male, age 61, both hemispheres 426.5
2070 Male, age 76, both hemispheres 421.3
Prepositus hypoglossal nucleus
nTPM: 446.2
2855 Female, age 85, right hemisphere 503.3
2086 Male, age 80, both hemispheres 389.1
Principal sensory trigeminal nucleus
nTPM: 483.2
2158 Male, age 61, both hemispheres 541.8
2367 Female, age 91, left hemisphere 481.3
2008 Male, age 80, left hemisphere 471.9
2324 Male, age 76, both hemispheres 437.8
Reticular pontine nucleus, caudal
nTPM: 474.9
2559 Male, age 74, both hemispheres 483.7
2332 Male, age 80, right hemisphere 477.8
2092 Male, age 76, both hemispheres 475.3
2457 Female, age 91, both hemispheres 462.8
Reticular pontine nucleus, oral
nTPM: 456.8
2012 Female, age 85, both hemispheres 484.8
2366 Female, age 91, both hemispheres 480.4
2361 Male, age 74, both hemispheres 459.6
1939 Male, age 80, both hemispheres 455.2
2167 Male, age 76, both hemispheres 404.1
Reticulotegmental nucleus
nTPM: 457.1
2452 Male, age 74, both hemispheres 471.6
2322 Female, age 91, both hemispheres 462.6
2325 Male, age 76, both hemispheres 456.9
2333 Male, age 80, both hemispheres 437.1
Spinal trigeminal nucleus, caudal
nTPM: 453.9
2390 Female, age 91, both hemispheres 537.4
2447 Male, age 76, both hemispheres 444.1
2312 Male, age 61, both hemispheres 436.2
2642 Male, age 74, both hemispheres 430.6
2308 Male, age 80, both hemispheres 421.1
Spinal trigeminal nucleus, interpolar
nTPM: 490.6
2625 Male, age 61, both hemispheres 579.4
2066 Male, age 76, right hemisphere 525.1
2389 Female, age 91, both hemispheres 471.7
2033 Male, age 80, both hemispheres 451.4
2386 Female, age 85, both hemispheres 425.3
Spinal trigeminal nucleus, oral
nTPM: 417.8
2164 Male, age 80, both hemispheres 463.4
2737 Female, age 85, both hemispheres 410.6
1978 Male, age 76, both hemispheres 379.5
Spinal vestibular nucleus
nTPM: 449.9
2384 Male, age 74, both hemispheres 469.7
2186 Female, age 91, both hemispheres 465.2
2806 Female, age 85, both hemispheres 463.1
2780 Male, age 80, both hemispheres 441.3
2748 Male, age 76, both hemispheres 438.3
2796 Male, age 61, both hemispheres 422.0
Subcoeruleus area
nTPM: 430.6
2369 Female, age 85, left hemisphere 458.8
1958 Male, age 80, both hemispheres 452.4
2089 Male, age 76, left hemisphere 425.9
2323 Female, age 91, left hemisphere 413.6
2451 Male, age 74, both hemispheres 402.3
Superior olive
nTPM: 491.4
1875 Female, age 85, both hemispheres 526.0
2020 Male, age 76, both hemispheres 491.6
2364 Male, age 74, right hemisphere 488.7
2561 Female, age 91, both hemispheres 479.2
2329 Male, age 80, right hemisphere 471.6
Superior vestibular nucleus
nTPM: 408.5
2015 Male, age 80, both hemispheres 448.7
2383 Male, age 74, both hemispheres 389.9
2061 Male, age 76, both hemispheres 387.0
Ventral medullary reticular nucleus
nTPM: 425.4
2372 Male, age 61, both hemispheres 445.8
2060 Male, age 76, both hemispheres 405.0
Ventral periolivary nuclei
nTPM: 461.0
2023 Male, age 76, both hemispheres 493.1
2165 Male, age 80, both hemispheres 491.2
2130 Female, age 85, both hemispheres 433.7
2794 Female, age 91, left hemisphere 426.0
Ventrolateral medulla, A1-C1 cell groups
nTPM: 449.4
2180 Male, age 61, both hemispheres 463.9
2741 Female, age 85, both hemispheres 462.3
1986 Male, age 76, both hemispheres 458.9
2302 Female, age 91, both hemispheres 437.7
2118 Male, age 80, both hemispheres 424.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 462.1
2449 Male, age 74, both hemispheres 485.5
2840 Female, age 85, both hemispheres 474.5
1959 Male, age 76, both hemispheres 463.5
2456 Female, age 91, both hemispheres 460.3
2161 Male, age 80, both hemispheres 451.7
2359 Male, age 61, both hemispheres 437.2

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1126.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 795.5
FF:10182-103D2 60 years, female 901.9
FF:10165-103B3 76 years, female 689.1
Medulla oblongata
Scaled Tags Per Million: 545.7
FF:10155-103A2 76 years, female 598.9
FF:10038-101F2 18-64 years, mixed 552.1
FF:10174-103C3 60 years, female 486.1
Pons
Scaled Tags Per Million: 1126.1
FF:10033-101E6 18-54 years, mixed 1126.1

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 549.7
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 476.9
Samples: 4

Max nTPM: 612.0
Min nTPM: 409.7
Sample A Female 612.0
Sample B Female 441.4
Sample C Male 444.4
Sample D Male 409.7
Pons
nTPM: 549.7
Samples: 4

Max nTPM: 634.5
Min nTPM: 396.9
Sample A Female 634.5
Sample B Female 396.9
Sample C Male 569.3
Sample D Male 598.0

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 357.0
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 357.0
Samples: 4

Max nTPM: 384.5
Min nTPM: 339.1
Sample A Male 340.6
Sample B Male 384.5
Sample C Female 339.1
Sample D Female 363.6

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.6
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 14.3
70805906 Antisense, RP_050725_02_E03, Mouse strain C57BL/6J (56 days, male) 15.7
68162204 Antisense, RP_041122_01_G02, Mouse strain C57BL/6J (56 days, male) 12.9
Pons
Expression energy: 14.6
70805906 Antisense, RP_050725_02_E03, Mouse strain C57BL/6J (56 days, male) 15.8
68162204 Antisense, RP_041122_01_G02, Mouse strain C57BL/6J (56 days, male) 13.5

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