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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:170.9 nTPM
HPA:170.9 nTPM
GTEx:156.9 nTPM
FANTOM5:373.0 Scaled Tags Per Million
Pig:222.3 nTPM
Mouse:92.8 nTPM
Allen mouse:1.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 170.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 137.5
2586 Male, age 75, left hemisphere 154.0
2828 Female, age 72, unknown 154.0
1870 Female, age 42, unknown 152.0
1833 Male, age 53, unknown 142.0
1827 Male, age 72, unknown 139.0
1830 Male, age 51, unknown 135.5
2411 Female, age 72, unknown 131.2
2666 Male, age 74, left hemisphere 125.5
2019 Male, age 18, unknown 124.5
2219 Male, age 76, both hemispheres 117.1
Dorsal raphe nucleus
nTPM: 157.6
2016 Female, age 72, unknown 176.0
2298 Female, age 72, unknown 164.4
1828 Male, age 53, unknown 161.3
2047 Male, age 72, unknown 151.0
2750 Male, age 76, both hemispheres 135.3
Inferior colliculus
nTPM: 152.5
1848 Female, age 42, unknown 161.4
2849 Male, age 72, unknown 154.7
2097 Female, age 72, unknown 150.6
1890 Male, age 53, unknown 143.3
Median raphe nucleus
nTPM: 144.3
2220 Male, age 76, midline 144.3
Pedunculopontine tegmental nucleus
nTPM: 148.7
2338 Male, age 61, both hemispheres 156.5
2334 Male, age 80, both hemispheres 153.4
1921 Female, age 85, both hemispheres 136.3
Periaquaductal grey, anterior
nTPM: 151.9
1795 Male, age 51, unknown 155.2
1947 Male, age 18, unknown 154.0
2502 Female, age 75, unknown 146.5
Periaquaductal grey, dorsal
nTPM: 165.5
2850 Male, age 76, both hemispheres 192.0
1840 Male, age 53, unknown 168.4
1831 Male, age 72, unknown 153.0
2464 Female, age 72, unknown 148.5
Periaquaductal grey, lateral
nTPM: 170.9
2140 Male, age 76, both hemispheres 178.5
2053 Male, age 18, unknown 170.1
2272 Male, age 74, both hemispheres 164.1
Pretectal area
nTPM: 149.5
2273 Male, age 74, both hemispheres 184.6
2224 Female, age 72, unknown 168.6
2316 Male, age 76, right hemisphere 156.9
2825 Male, age 18, unknown 156.3
2667 Female, age 75, unknown 153.3
1944 Female, age 72, unknown 144.7
2407 Male, age 75, both hemispheres 144.6
1817 Female, age 42, unknown 142.3
1815 Male, age 53, unknown 137.2
1816 Male, age 51, unknown 134.5
2007 Male, age 72, unknown 121.3
Red nucleus
nTPM: 144.9
2725 Female, age 75, unknown 159.8
1954 Female, age 42, unknown 158.1
1821 Female, age 72, unknown 155.5
2769 Male, age 72, unknown 152.5
2227 Male, age 72, unknown 150.9
2503 Female, age 72, unknown 150.8
1865 Male, age 51, unknown 150.7
1904 Male, age 53, unknown 144.3
2823 Male, age 76, right hemisphere 143.3
2785 Male, age 18, unknown 127.5
2588 Male, age 74, left hemisphere 122.8
2584 Male, age 75, left hemisphere 122.6
Substantia nigra
nTPM: 148.1
2699 Male, age 18, unknown 190.3
1916 Female, age 42, unknown 160.4
2241 Male, age 72, unknown 155.0
1851 Male, age 51, unknown 151.3
2409 Female, age 72, unknown 145.5
1889 Female, age 72, unknown 142.7
1941 Male, age 53, unknown 138.4
2590 Female, age 75, unknown 138.2
2583 Male, age 75, right hemisphere 129.8
2665 Male, age 74, both hemispheres 129.7
Superior colliculus
nTPM: 145.4
1995 Male, age 72, unknown 163.1
1796 Male, age 53, unknown 154.6
1913 Female, age 42, unknown 152.7
2587 Male, age 74, left hemisphere 148.4
1839 Male, age 51, unknown 146.4
2087 Female, age 72, unknown 143.4
2664 Male, age 75, both hemispheres 138.7
2668 Female, age 75, unknown 138.3
2261 Male, age 18, unknown 137.0
1895 Male, age 76, right hemisphere 131.3
Ventral tegmental area
nTPM: 149.1
1915 Female, age 42, unknown 160.6
2021 Male, age 53, unknown 152.5
2218 Male, age 76, both hemispheres 147.2
2223 Female, age 72, unknown 147.0
1942 Male, age 51, unknown 146.7
2410 Female, age 72, unknown 140.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 156.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 156.9
Samples: 139

Max nTPM: 659.5
Min nTPM: 37.1
Std nTPM: 89.8
Median nTPM: 133.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 659.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 543.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 422.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 378.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 371.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 364.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 348.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 325.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 321.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 319.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 295.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 290.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 283.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 258.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 252.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 246.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 245.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 244.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 236.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 234.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 231.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 211.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 211.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 210.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 207.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 203.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 197.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 196.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 195.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 193.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 191.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 187.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 186.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 186.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 181.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 180.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 170.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 162.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 160.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 159.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 159.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 157.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 155.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 154.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 154.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 154.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 152.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 152.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 150.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 149.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 148.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 147.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 147.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 146.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 146.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 146.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 145.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 144.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 144.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 142.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 142.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 142.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 141.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 140.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 136.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 136.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 135.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 135.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 134.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 133.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 132.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 131.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 130.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 130.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 126.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 125.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 125.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 124.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 124.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 124.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 124.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 121.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 121.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 120.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 120.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 120.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 120.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 119.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 118.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 118.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 115.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 114.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 114.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 111.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 110.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 109.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 109.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 109.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 108.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 107.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 106.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 105.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 105.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 104.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 104.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 102.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 100.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 100.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 99.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 98.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 97.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 97.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 96.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 95.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 94.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 94.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 93.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 92.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 91.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 91.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 91.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 86.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 85.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 84.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 83.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 82.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 81.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 80.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 79.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 74.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 74.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 65.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 62.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 62.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 60.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 48.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 37.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 373.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 373.0
FF:10158-103A5 76 years, female 373.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 222.3
Pig sample Sample description nTPM
Midbrain
nTPM: 222.3
Samples: 4

Max nTPM: 425.3
Min nTPM: 128.0
Sample A Female 425.3
Sample B Female 192.6
Sample C Male 143.2
Sample D Male 128.0
Periaqueductal gray
nTPM: 203.5
Samples: 3

Max nTPM: 229.1
Min nTPM: 189.7
Sample B Female 189.7
Sample C Male 229.1
Sample D Male 191.8
Substantia nigra
nTPM: 218.6
Samples: 4

Max nTPM: 243.2
Min nTPM: 195.0
Sample A Female 243.2
Sample B Female 211.4
Sample C Male 195.0
Sample D Male 224.9
Superior colliculi
nTPM: 163.5
Samples: 4

Max nTPM: 191.1
Min nTPM: 141.7
Sample A Female 191.1
Sample B Female 141.7
Sample C Male 162.2
Sample D Male 159.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 92.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 92.8
Samples: 4

Max nTPM: 99.8
Min nTPM: 88.0
Sample A Male 99.8
Sample B Male 91.6
Sample C Female 88.0
Sample D Female 91.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.8
74822928 Antisense, RP_060321_01_A01, Mouse strain C57BL/6J (56 days, male) 1.8

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