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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:198.3 nTPM
HPA:198.3 nTPM
GTEx:152.4 nTPM
FANTOM5:205.2 Scaled Tags Per Million
Pig:86.5 nTPM
Mouse:78.1 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 198.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 166.6
2411 Female, age 72, unknown 180.5
2586 Male, age 75, left hemisphere 173.0
1833 Male, age 53, unknown 172.8
2828 Female, age 72, unknown 167.7
1870 Female, age 42, unknown 167.1
1827 Male, age 72, unknown 165.5
1830 Male, age 51, unknown 165.3
2219 Male, age 76, both hemispheres 165.2
2019 Male, age 18, unknown 156.3
2666 Male, age 74, left hemisphere 152.8
Dorsal raphe nucleus
nTPM: 193.3
2298 Female, age 72, unknown 205.6
2016 Female, age 72, unknown 203.8
1828 Male, age 53, unknown 195.0
2047 Male, age 72, unknown 192.3
2750 Male, age 76, both hemispheres 169.7
Inferior colliculus
nTPM: 197.7
2097 Female, age 72, unknown 210.3
1890 Male, age 53, unknown 201.3
1848 Female, age 42, unknown 190.2
2849 Male, age 72, unknown 189.1
Median raphe nucleus
nTPM: 170.1
2220 Male, age 76, midline 170.1
Pedunculopontine tegmental nucleus
nTPM: 179.1
1921 Female, age 85, both hemispheres 186.7
2334 Male, age 80, both hemispheres 181.8
2338 Male, age 61, both hemispheres 168.7
Periaquaductal grey, anterior
nTPM: 174.6
2502 Female, age 75, unknown 187.4
1947 Male, age 18, unknown 168.9
1795 Male, age 51, unknown 167.6
Periaquaductal grey, dorsal
nTPM: 198.3
1840 Male, age 53, unknown 216.9
2850 Male, age 76, both hemispheres 200.5
2464 Female, age 72, unknown 195.8
1831 Male, age 72, unknown 179.7
Periaquaductal grey, lateral
nTPM: 182.2
2140 Male, age 76, both hemispheres 189.0
2053 Male, age 18, unknown 187.8
2272 Male, age 74, both hemispheres 169.7
Pretectal area
nTPM: 170.4
2273 Male, age 74, both hemispheres 189.1
2667 Female, age 75, unknown 179.9
2224 Female, age 72, unknown 176.0
2825 Male, age 18, unknown 175.9
2316 Male, age 76, right hemisphere 171.0
1944 Female, age 72, unknown 168.9
2407 Male, age 75, both hemispheres 168.1
1816 Male, age 51, unknown 167.9
1817 Female, age 42, unknown 164.8
1815 Male, age 53, unknown 159.4
2007 Male, age 72, unknown 153.3
Red nucleus
nTPM: 166.6
1821 Female, age 72, unknown 176.1
1954 Female, age 42, unknown 173.7
2503 Female, age 72, unknown 170.2
2769 Male, age 72, unknown 170.0
2823 Male, age 76, right hemisphere 170.0
2227 Male, age 72, unknown 169.6
1904 Male, age 53, unknown 165.8
2725 Female, age 75, unknown 165.4
1865 Male, age 51, unknown 165.3
2588 Male, age 74, left hemisphere 159.4
2584 Male, age 75, left hemisphere 158.4
2785 Male, age 18, unknown 155.4
Substantia nigra
nTPM: 179.4
2699 Male, age 18, unknown 207.5
2241 Male, age 72, unknown 199.5
1916 Female, age 42, unknown 184.2
1851 Male, age 51, unknown 178.5
2409 Female, age 72, unknown 176.5
2590 Female, age 75, unknown 173.4
1889 Female, age 72, unknown 172.7
1941 Male, age 53, unknown 168.4
2665 Male, age 74, both hemispheres 166.5
2583 Male, age 75, right hemisphere 166.3
Superior colliculus
nTPM: 174.5
1995 Male, age 72, unknown 193.0
2664 Male, age 75, both hemispheres 183.9
1913 Female, age 42, unknown 178.6
1839 Male, age 51, unknown 176.6
2587 Male, age 74, left hemisphere 175.6
2261 Male, age 18, unknown 174.0
1796 Male, age 53, unknown 171.2
2087 Female, age 72, unknown 170.3
1895 Male, age 76, right hemisphere 162.2
2668 Female, age 75, unknown 159.3
Ventral tegmental area
nTPM: 176.5
1942 Male, age 51, unknown 183.3
1915 Female, age 42, unknown 179.0
2021 Male, age 53, unknown 177.0
2410 Female, age 72, unknown 175.3
2218 Male, age 76, both hemispheres 174.2
2223 Female, age 72, unknown 169.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 152.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 152.4
Samples: 139

Max nTPM: 370.8
Min nTPM: 39.4
Std nTPM: 66.5
Median nTPM: 143.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 370.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 347.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 316.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 304.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 299.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 284.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 283.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 271.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 267.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 265.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 262.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 245.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 244.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 244.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 238.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 235.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 234.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 232.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 224.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 224.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 222.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 221.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 218.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 216.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 212.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 210.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 207.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 204.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 203.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 202.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 202.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 200.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 197.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 197.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 197.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 195.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 195.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 189.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 188.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 187.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 187.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 182.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 180.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 179.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 179.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 178.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 178.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 177.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 172.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 167.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 166.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 166.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 166.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 166.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 163.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 163.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 162.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 156.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 155.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 150.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 150.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 150.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 149.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 149.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 146.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 146.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 146.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 145.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 145.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 143.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 143.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 142.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 138.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 136.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 134.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 133.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 131.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 131.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 130.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 130.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 127.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 127.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 125.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 125.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 123.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 122.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 121.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 119.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 118.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 118.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 117.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 115.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 113.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 113.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 110.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 107.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 106.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 106.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 104.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 103.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 100.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 99.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 98.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 98.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 96.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 95.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 93.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 91.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 87.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 86.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 85.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 85.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 83.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 81.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 80.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 79.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 78.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 76.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 74.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 71.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 70.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 66.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 66.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 64.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 64.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 63.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 59.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 57.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 43.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 39.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 205.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 205.2
FF:10158-103A5 76 years, female 205.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 86.5
Pig sample Sample description nTPM
Midbrain
nTPM: 86.6
Samples: 4

Max nTPM: 164.2
Min nTPM: 54.3
Sample A Female 164.2
Sample B Female 70.8
Sample C Male 56.9
Sample D Male 54.3
Periaqueductal gray
nTPM: 66.4
Samples: 3

Max nTPM: 68.9
Min nTPM: 61.6
Sample B Female 61.6
Sample C Male 68.9
Sample D Male 68.7
Substantia nigra
nTPM: 83.7
Samples: 4

Max nTPM: 105.0
Min nTPM: 72.4
Sample A Female 105.0
Sample B Female 79.2
Sample C Male 72.4
Sample D Male 78.1
Superior colliculi
nTPM: 83.3
Samples: 4

Max nTPM: 101.6
Min nTPM: 76.8
Sample A Female 101.6
Sample B Female 77.9
Sample C Male 76.8
Sample D Male 76.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 78.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 78.1
Samples: 4

Max nTPM: 84.7
Min nTPM: 70.7
Sample A Male 80.6
Sample B Male 70.7
Sample C Female 76.3
Sample D Female 84.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
686199 Antisense, RP_040916_01_A07, Mouse strain C57BL/6J (56 days, male) 0.7

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