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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 76.8
Min nTPM: 29.8
Std nTPM: 11.0
Median nTPM:
413_1
59 years, female
76.8
149_1
88 years, male
73.9
42_1
85 years, male
73.1
501_1
88 years, male
72.5
89_1
63 years, male
71.8
81_1
67 years, male
70.7
139_1
64 years, female
69.6
490_1
67 years, female
67.4
137_1
83 years, male
67.0
32_1
67 years, male
63.2
162_1
79 years, female
63.1
35_1
74 years, female
62.7
2_1
77 years, female
62.5
217_1
76 years, male
62.2
145_1
84 years, male
61.7
153_1
70 years, female
61.4
466_1
57 years, female
60.6
4_1
88 years, female
60.4
126_1
63 years, male
59.7
43_1
64 years, female
59.2
17_1
71 years, male
58.7
491_1
89 years, female
57.1
415_1
77 years, female
56.7
142_1
61 years, female
56.4
18_1
88 years, male
55.9
119_1
70 years, female
55.8
314_1
67 years, male
55.8
117_1
61 years, male
55.6
109_1
81 years, female
55.3
414_1
84 years, female
55.3
324_1
76 years, male
53.6
315_1
62 years, female
53.3
316_1
62 years, male
52.8
396_1
62 years, male
51.7
9_1
66 years, female
51.6
120_1
70 years, female
51.5
495_1
57 years, female
51.3
265_1
87 years, male
50.8
480_1
63 years, male
50.2
518_1
75 years, female
50.1
115_1
83 years, male
49.9
288_1
66 years, female
49.2
311_1
78 years, male
48.0
499_1
55 years, female
47.9
6_1
73 years, female
47.8
321_1
62 years, female
47.7
254_1
77 years, female
47.5
313_1
79 years, female
47.5
286_1
68 years, female
47.2
468_1
89 years, male
47.1
99_1
64 years, male
46.6
506_1
65 years, male
46.4
307_1
66 years, female
45.5
295_1
61 years, female
45.4
291_1
76 years, male
44.8
322_1
76 years, male
44.5
237_1
82 years, male
44.0
335_1
73 years, female
43.9
246_1
77 years, male
43.7
320_1
89 years, female
43.7
348_1
84 years, male
43.7
376_1
75 years, female
43.2
405_1
91 years, male
43.2
251_1
78 years, male
43.0
229_1
69 years, female
42.6
406_1
79 years, male
42.6
319_1
81 years, male
42.3
517_1
88 years, male
42.3
503_1
68 years, male
41.9
41_1
94 years, female
41.8
292_1
71 years, male
41.8
266_1
85 years, male
41.4
384_1
83 years, male
40.8
243_1
75 years, male
40.7
189_1
76 years, male
40.5
293_1
68 years, female
40.4
375_1
74 years, female
40.4
308_1
70 years, female
40.3
264_1
73 years, female
40.1
318_1
68 years, male
40.1
379_1
60 years, male
39.6
447_1
81 years, male
39.6
526_1
61 years, male
39.3
389_1
86 years, female
38.8
173_1
67 years, male
38.3
351_1
91 years, male
37.7
404_1
82 years, female
37.3
386_1
76 years, male
37.2
394_1
75 years, female
37.1
347_1
72 years, male
36.8
377_1
82 years, female
36.7
452_1
88 years, female
36.5
355_1
70 years, female
36.4
356_1
87 years, female
35.9
172_1
72 years, female
35.4
350_1
84 years, female
34.9
349_1
83 years, male
34.6
177_1
74 years, male
34.2
317_1
60 years, male
33.8
352_1
62 years, male
33.5
163_1
78 years, male
33.3
353_1
82 years, female
33.2
354_1
81 years, female
33.0
218_1
71 years, female
32.0
425_1
59 years, female
29.8
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
