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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:49.7 nTPM
HPA:49.7 nTPM
GTEx:33.4 nTPM
FANTOM5:55.4 Scaled Tags Per Million
Pig:17.9 nTPM
Mouse:57.8 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 49.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 46.3
1833 Male, age 53, unknown 48.0
2219 Male, age 76, both hemispheres 48.0
1827 Male, age 72, unknown 47.5
2666 Male, age 74, left hemisphere 47.4
2411 Female, age 72, unknown 47.2
1870 Female, age 42, unknown 47.0
1830 Male, age 51, unknown 46.8
2019 Male, age 18, unknown 46.0
2828 Female, age 72, unknown 43.8
2586 Male, age 75, left hemisphere 41.2
Dorsal raphe nucleus
nTPM: 45.9
2750 Male, age 76, both hemispheres 49.2
1828 Male, age 53, unknown 46.0
2047 Male, age 72, unknown 45.3
2298 Female, age 72, unknown 44.5
2016 Female, age 72, unknown 44.4
Inferior colliculus
nTPM: 46.7
1890 Male, age 53, unknown 47.7
2849 Male, age 72, unknown 47.2
1848 Female, age 42, unknown 46.1
2097 Female, age 72, unknown 46.1
Median raphe nucleus
nTPM: 49.7
2220 Male, age 76, midline 49.7
Pedunculopontine tegmental nucleus
nTPM: 49.1
2338 Male, age 61, both hemispheres 51.3
1921 Female, age 85, both hemispheres 48.3
2334 Male, age 80, both hemispheres 47.6
Periaquaductal grey, anterior
nTPM: 44.9
1795 Male, age 51, unknown 45.8
1947 Male, age 18, unknown 45.3
2502 Female, age 75, unknown 43.6
Periaquaductal grey, dorsal
nTPM: 46.5
1831 Male, age 72, unknown 47.5
2464 Female, age 72, unknown 47.2
2850 Male, age 76, both hemispheres 46.8
1840 Male, age 53, unknown 44.6
Periaquaductal grey, lateral
nTPM: 47.5
2272 Male, age 74, both hemispheres 49.9
2053 Male, age 18, unknown 46.7
2140 Male, age 76, both hemispheres 45.8
Pretectal area
nTPM: 47.8
2273 Male, age 74, both hemispheres 50.9
2667 Female, age 75, unknown 50.4
2825 Male, age 18, unknown 48.4
1815 Male, age 53, unknown 48.3
1816 Male, age 51, unknown 48.2
1944 Female, age 72, unknown 48.2
2224 Female, age 72, unknown 47.1
2407 Male, age 75, both hemispheres 47.1
2007 Male, age 72, unknown 47.0
2316 Male, age 76, right hemisphere 45.5
1817 Female, age 42, unknown 44.9
Red nucleus
nTPM: 48.2
2823 Male, age 76, right hemisphere 52.8
1904 Male, age 53, unknown 49.1
2725 Female, age 75, unknown 49.0
2503 Female, age 72, unknown 48.9
2227 Male, age 72, unknown 48.6
1865 Male, age 51, unknown 48.1
2588 Male, age 74, left hemisphere 47.9
1821 Female, age 72, unknown 47.1
1954 Female, age 42, unknown 47.1
2769 Male, age 72, unknown 47.1
2584 Male, age 75, left hemisphere 46.3
2785 Male, age 18, unknown 46.0
Substantia nigra
nTPM: 46.2
1941 Male, age 53, unknown 48.0
2409 Female, age 72, unknown 47.0
2699 Male, age 18, unknown 47.0
1889 Female, age 72, unknown 46.9
2583 Male, age 75, right hemisphere 46.9
1916 Female, age 42, unknown 46.2
2241 Male, age 72, unknown 46.2
2590 Female, age 75, unknown 45.9
1851 Male, age 51, unknown 44.1
2665 Male, age 74, both hemispheres 43.5
Superior colliculus
nTPM: 46.1
1895 Male, age 76, right hemisphere 50.9
1913 Female, age 42, unknown 49.1
2587 Male, age 74, left hemisphere 47.4
2087 Female, age 72, unknown 46.7
2261 Male, age 18, unknown 46.7
1839 Male, age 51, unknown 45.0
1995 Male, age 72, unknown 44.8
2668 Female, age 75, unknown 44.6
1796 Male, age 53, unknown 44.5
2664 Male, age 75, both hemispheres 41.1
Ventral tegmental area
nTPM: 45.7
2218 Male, age 76, both hemispheres 47.2
2223 Female, age 72, unknown 47.2
1942 Male, age 51, unknown 46.6
1915 Female, age 42, unknown 45.3
2410 Female, age 72, unknown 44.6
2021 Male, age 53, unknown 43.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 33.4
Samples: 139

Max nTPM: 73.3
Min nTPM: 11.1
Std nTPM: 12.2
Median nTPM: 32.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 73.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 69.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 67.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 66.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 65.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 58.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 54.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 50.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 50.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 49.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 47.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 47.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 46.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 46.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 46.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 46.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 46.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 46.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 45.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 45.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 44.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 44.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 44.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 44.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 42.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 41.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 41.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 40.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 40.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 40.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 39.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 39.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 38.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 38.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 38.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 38.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 38.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 37.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 37.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 36.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 36.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 36.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 36.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 36.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 35.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 35.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 35.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 34.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 34.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 33.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 33.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 33.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 33.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 32.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 32.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 32.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 31.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 31.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 30.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 30.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 30.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 29.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 29.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 29.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 28.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 28.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 28.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 28.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 27.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 27.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 27.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 27.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 26.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 26.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 26.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 26.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 26.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 26.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 26.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 25.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 25.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 25.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 25.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 25.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 24.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 24.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 23.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 23.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 23.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 22.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 22.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 22.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 22.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 21.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 21.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 21.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 21.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 20.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 20.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 20.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 20.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 20.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 20.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 20.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 20.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 20.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 20.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 20.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 19.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 18.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 18.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 17.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 16.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 15.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 12.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 11.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 55.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 55.4
FF:10158-103A5 76 years, female 55.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 17.9
Pig sample Sample description nTPM
Midbrain
nTPM: 17.1
Samples: 4

Max nTPM: 23.4
Min nTPM: 14.2
Sample A Female 16.7
Sample B Female 14.2
Sample C Male 14.2
Sample D Male 23.4
Periaqueductal gray
nTPM: 14.9
Samples: 3

Max nTPM: 16.7
Min nTPM: 13.2
Sample B Female 13.2
Sample C Male 14.7
Sample D Male 16.7
Substantia nigra
nTPM: 15.1
Samples: 4

Max nTPM: 21.1
Min nTPM: 11.2
Sample A Female 21.1
Sample B Female 11.2
Sample C Male 15.4
Sample D Male 12.8
Superior colliculi
nTPM: 17.9
Samples: 4

Max nTPM: 20.2
Min nTPM: 15.0
Sample A Female 20.2
Sample B Female 15.0
Sample C Male 16.3
Sample D Male 20.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 57.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 57.9
Samples: 4

Max nTPM: 69.1
Min nTPM: 50.4
Sample A Male 69.1
Sample B Male 50.4
Sample C Female 50.4
Sample D Female 61.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
74988760 Antisense, RP_060315_05_H04, Mouse strain C57BL/6J (56 days, male) 0.1
70724529 Antisense, RP_050705_02_A04, Mouse strain C57BL/6J (56 days, male) 0.0

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