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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 175.6
Min nTPM: 50.9
Std nTPM: 22.4
Median nTPM:
490_1
67 years, female
175.6
491_1
89 years, female
169.6
413_1
59 years, female
157.7
149_1
88 years, male
151.0
32_1
67 years, male
144.4
495_1
57 years, female
144.4
142_1
61 years, female
133.0
501_1
88 years, male
132.8
139_1
64 years, female
131.2
315_1
62 years, female
130.9
415_1
77 years, female
130.4
466_1
57 years, female
129.0
43_1
64 years, female
126.2
162_1
79 years, female
125.2
109_1
81 years, female
125.1
81_1
67 years, male
124.8
126_1
63 years, male
121.3
414_1
84 years, female
121.2
17_1
71 years, male
120.1
313_1
79 years, female
119.9
42_1
85 years, male
118.2
4_1
88 years, female
117.8
153_1
70 years, female
115.9
89_1
63 years, male
115.4
18_1
88 years, male
113.8
117_1
61 years, male
113.3
9_1
66 years, female
112.3
137_1
83 years, male
111.2
119_1
70 years, female
110.8
468_1
89 years, male
110.6
2_1
77 years, female
110.5
35_1
74 years, female
110.2
316_1
62 years, male
109.8
120_1
70 years, female
109.4
518_1
75 years, female
109.4
324_1
76 years, male
107.7
217_1
76 years, male
105.3
322_1
76 years, male
105.0
145_1
84 years, male
103.9
6_1
73 years, female
103.2
266_1
85 years, male
103.1
115_1
83 years, male
102.3
265_1
87 years, male
102.2
288_1
66 years, female
101.1
311_1
78 years, male
100.3
307_1
66 years, female
99.6
499_1
55 years, female
99.0
314_1
67 years, male
98.9
396_1
62 years, male
97.8
319_1
81 years, male
96.6
348_1
84 years, male
96.5
526_1
61 years, male
96.4
375_1
74 years, female
96.3
254_1
77 years, female
94.7
389_1
86 years, female
94.6
251_1
78 years, male
94.2
480_1
63 years, male
94.2
286_1
68 years, female
94.0
246_1
77 years, male
92.7
405_1
91 years, male
92.7
347_1
72 years, male
92.1
321_1
62 years, female
91.7
99_1
64 years, male
91.2
320_1
89 years, female
91.1
237_1
82 years, male
90.4
379_1
60 years, male
90.1
404_1
82 years, female
90.0
447_1
81 years, male
89.7
517_1
88 years, male
89.0
425_1
59 years, female
88.4
503_1
68 years, male
88.3
41_1
94 years, female
88.2
377_1
82 years, female
86.6
308_1
70 years, female
86.2
264_1
73 years, female
86.1
354_1
81 years, female
85.2
335_1
73 years, female
85.0
406_1
79 years, male
84.8
292_1
71 years, male
84.5
386_1
76 years, male
84.3
384_1
83 years, male
83.5
349_1
83 years, male
83.4
243_1
75 years, male
83.3
229_1
69 years, female
83.1
352_1
62 years, male
82.4
506_1
65 years, male
81.9
350_1
84 years, female
81.0
452_1
88 years, female
80.4
355_1
70 years, female
80.3
291_1
76 years, male
79.8
293_1
68 years, female
79.8
394_1
75 years, female
79.8
189_1
76 years, male
79.7
351_1
91 years, male
77.4
353_1
82 years, female
76.9
356_1
87 years, female
75.2
173_1
67 years, male
74.9
295_1
61 years, female
74.9
376_1
75 years, female
74.4
172_1
72 years, female
73.7
317_1
60 years, male
73.3
318_1
68 years, male
70.3
177_1
74 years, male
59.6
163_1
78 years, male
54.9
218_1
71 years, female
50.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
