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RPL23
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:901.9 nTPM
HPA:901.9 nTPM
GTEx:914.6 nTPM
FANTOM5:285.8 Scaled Tags Per Million
Pig:426.2 nTPM
Mouse:333.4 nTPM
Allen mouse:10.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 901.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 871.8
1870 Female, age 42, unknown 894.7
2666 Male, age 74, left hemisphere 886.2
2411 Female, age 72, unknown 877.5
1827 Male, age 72, unknown 876.2
1833 Male, age 53, unknown 874.9
1830 Male, age 51, unknown 874.8
2828 Female, age 72, unknown 872.4
2219 Male, age 76, both hemispheres 859.9
2019 Male, age 18, unknown 851.5
2586 Male, age 75, left hemisphere 850.1
Dorsal raphe nucleus
nTPM: 875.0
2298 Female, age 72, unknown 891.9
2016 Female, age 72, unknown 877.3
2750 Male, age 76, both hemispheres 873.7
1828 Male, age 53, unknown 871.2
2047 Male, age 72, unknown 861.0
Inferior colliculus
nTPM: 876.6
2849 Male, age 72, unknown 881.3
1890 Male, age 53, unknown 878.3
1848 Female, age 42, unknown 874.0
2097 Female, age 72, unknown 872.6
Median raphe nucleus
nTPM: 889.1
2220 Male, age 76, midline 889.1
Pedunculopontine tegmental nucleus
nTPM: 901.9
2338 Male, age 61, both hemispheres 935.7
2334 Male, age 80, both hemispheres 901.2
1921 Female, age 85, both hemispheres 868.9
Periaquaductal grey, anterior
nTPM: 868.2
2502 Female, age 75, unknown 881.1
1947 Male, age 18, unknown 865.5
1795 Male, age 51, unknown 857.9
Periaquaductal grey, dorsal
nTPM: 880.1
2850 Male, age 76, both hemispheres 889.9
1840 Male, age 53, unknown 887.4
1831 Male, age 72, unknown 883.5
2464 Female, age 72, unknown 859.8
Periaquaductal grey, lateral
nTPM: 869.4
2053 Male, age 18, unknown 883.2
2140 Male, age 76, both hemispheres 864.8
2272 Male, age 74, both hemispheres 860.3
Pretectal area
nTPM: 863.1
2825 Male, age 18, unknown 881.9
2224 Female, age 72, unknown 876.8
1815 Male, age 53, unknown 872.3
2316 Male, age 76, right hemisphere 872.2
1817 Female, age 42, unknown 862.9
2273 Male, age 74, both hemispheres 861.0
1944 Female, age 72, unknown 857.0
2407 Male, age 75, both hemispheres 856.9
1816 Male, age 51, unknown 856.5
2007 Male, age 72, unknown 851.9
2667 Female, age 75, unknown 844.5
Red nucleus
nTPM: 881.3
2503 Female, age 72, unknown 903.1
1821 Female, age 72, unknown 901.7
1865 Male, age 51, unknown 899.1
2725 Female, age 75, unknown 894.8
1904 Male, age 53, unknown 884.9
1954 Female, age 42, unknown 879.8
2227 Male, age 72, unknown 878.3
2769 Male, age 72, unknown 877.7
2588 Male, age 74, left hemisphere 872.1
2823 Male, age 76, right hemisphere 868.0
2584 Male, age 75, left hemisphere 863.1
2785 Male, age 18, unknown 852.4
Substantia nigra
nTPM: 892.4
2699 Male, age 18, unknown 926.1
2409 Female, age 72, unknown 910.4
2665 Male, age 74, both hemispheres 906.9
1851 Male, age 51, unknown 903.8
2241 Male, age 72, unknown 901.9
1916 Female, age 42, unknown 889.1
2590 Female, age 75, unknown 887.2
1889 Female, age 72, unknown 881.6
1941 Male, age 53, unknown 873.1
2583 Male, age 75, right hemisphere 843.8
Superior colliculus
nTPM: 873.2
2587 Male, age 74, left hemisphere 918.1
1913 Female, age 42, unknown 885.7
1995 Male, age 72, unknown 880.0
1895 Male, age 76, right hemisphere 876.0
2668 Female, age 75, unknown 870.2
1839 Male, age 51, unknown 869.2
1796 Male, age 53, unknown 865.1
2261 Male, age 18, unknown 864.8
2087 Female, age 72, unknown 853.2
2664 Male, age 75, both hemispheres 849.2
Ventral tegmental area
nTPM: 890.5
1915 Female, age 42, unknown 908.3
2223 Female, age 72, unknown 900.3
2410 Female, age 72, unknown 891.0
2021 Male, age 53, unknown 889.5
1942 Male, age 51, unknown 877.9
2218 Male, age 76, both hemispheres 875.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 914.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 914.6
Samples: 139

Max nTPM: 2213.0
Min nTPM: 430.8
Std nTPM: 296.1
Median nTPM: 881.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2213.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2026.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1898.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1686.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1660.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1584.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1431.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1425.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1358.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1354.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1313.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1265.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1259.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1252.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1248.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1241.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1234.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1216.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1215.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1206.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1191.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1165.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1159.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1135.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1128.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1110.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1097.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1092.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1082.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1065.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1055.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1046.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1046.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1037.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1022.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1021.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1019.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1018.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1010.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1003.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1002.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 993.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 992.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 989.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 984.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 983.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 983.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 976.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 973.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 968.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 968.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 966.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 964.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 963.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 962.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 956.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 955.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 942.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 934.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 930.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 921.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 915.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 913.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 904.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 901.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 895.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 886.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 885.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 884.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 881.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 870.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 864.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 855.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 852.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 846.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 844.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 843.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 839.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 830.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 821.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 815.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 812.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 804.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 798.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 795.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 789.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 788.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 785.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 779.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 779.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 776.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 772.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 768.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 767.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 765.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 765.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 764.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 744.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 738.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 726.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 723.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 717.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 716.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 701.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 700.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 689.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 687.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 682.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 679.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 665.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 662.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 660.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 647.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 646.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 643.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 641.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 640.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 632.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 629.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 626.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 625.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 624.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 614.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 607.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 599.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 592.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 591.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 587.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 585.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 578.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 572.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 559.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 555.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 551.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 546.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 531.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 531.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 453.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 430.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 285.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 285.8
FF:10158-103A5 76 years, female 285.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 426.2
Pig sample Sample description nTPM
Midbrain
nTPM: 382.3
Samples: 4

Max nTPM: 448.8
Min nTPM: 316.0
Sample A Female 446.5
Sample B Female 448.8
Sample C Male 317.8
Sample D Male 316.0
Periaqueductal gray
nTPM: 350.1
Samples: 3

Max nTPM: 371.5
Min nTPM: 326.9
Sample B Female 352.0
Sample C Male 371.5
Sample D Male 326.9
Substantia nigra
nTPM: 426.2
Samples: 4

Max nTPM: 537.5
Min nTPM: 340.4
Sample A Female 537.5
Sample B Female 428.3
Sample C Male 398.4
Sample D Male 340.4
Superior colliculi
nTPM: 394.3
Samples: 4

Max nTPM: 439.4
Min nTPM: 357.6
Sample A Female 439.4
Sample B Female 357.6
Sample C Male 404.9
Sample D Male 375.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 333.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 333.4
Samples: 4

Max nTPM: 360.0
Min nTPM: 310.6
Sample A Male 360.0
Sample B Male 333.2
Sample C Female 310.6
Sample D Female 329.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.5
68441454 Antisense, RP_041214_02_D04, Mouse strain C57BL/6J (56 days, male) 12.0
74819237 Antisense, RP_060315_02_C01, Mouse strain C57BL/6J (56 days, male) 10.0
70813131 Antisense, RP_050712_03_C03, Mouse strain C57BL/6J (56 days, male) 9.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.