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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:61.8 nTPM
HPA:61.8 nTPM
GTEx:55.1 nTPM
FANTOM5:160.2 Scaled Tags Per Million
Pig:185.6 nTPM
Mouse:44.0 nTPM
Allen mouse:3.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 61.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 59.2
2019 Male, age 18, unknown 64.5
1830 Male, age 51, unknown 61.1
2219 Male, age 76, both hemispheres 61.1
2666 Male, age 74, left hemisphere 60.2
1833 Male, age 53, unknown 59.3
2828 Female, age 72, unknown 59.3
1870 Female, age 42, unknown 57.8
2586 Male, age 75, left hemisphere 57.4
1827 Male, age 72, unknown 55.9
2411 Female, age 72, unknown 55.5
Dorsal raphe nucleus
nTPM: 55.8
1828 Male, age 53, unknown 58.2
2750 Male, age 76, both hemispheres 58.2
2016 Female, age 72, unknown 55.9
2047 Male, age 72, unknown 54.6
2298 Female, age 72, unknown 51.9
Inferior colliculus
nTPM: 57.6
2849 Male, age 72, unknown 63.0
1848 Female, age 42, unknown 58.9
1890 Male, age 53, unknown 55.4
2097 Female, age 72, unknown 53.0
Median raphe nucleus
nTPM: 60.1
2220 Male, age 76, midline 60.1
Pedunculopontine tegmental nucleus
nTPM: 58.4
2334 Male, age 80, both hemispheres 59.0
2338 Male, age 61, both hemispheres 58.9
1921 Female, age 85, both hemispheres 57.4
Periaquaductal grey, anterior
nTPM: 56.6
1947 Male, age 18, unknown 57.8
2502 Female, age 75, unknown 56.3
1795 Male, age 51, unknown 55.9
Periaquaductal grey, dorsal
nTPM: 57.4
2850 Male, age 76, both hemispheres 63.1
1831 Male, age 72, unknown 57.1
2464 Female, age 72, unknown 55.9
1840 Male, age 53, unknown 53.6
Periaquaductal grey, lateral
nTPM: 56.2
2140 Male, age 76, both hemispheres 58.4
2272 Male, age 74, both hemispheres 55.6
2053 Male, age 18, unknown 54.6
Pretectal area
nTPM: 57.0
2407 Male, age 75, both hemispheres 61.6
2316 Male, age 76, right hemisphere 58.9
1817 Female, age 42, unknown 58.4
1815 Male, age 53, unknown 58.0
1944 Female, age 72, unknown 56.9
1816 Male, age 51, unknown 56.7
2667 Female, age 75, unknown 55.8
2273 Male, age 74, both hemispheres 55.6
2007 Male, age 72, unknown 55.2
2825 Male, age 18, unknown 55.2
2224 Female, age 72, unknown 54.5
Red nucleus
nTPM: 61.8
1821 Female, age 72, unknown 63.8
1904 Male, age 53, unknown 63.4
2769 Male, age 72, unknown 62.8
2584 Male, age 75, left hemisphere 62.5
2785 Male, age 18, unknown 61.9
1954 Female, age 42, unknown 61.7
2725 Female, age 75, unknown 61.4
2227 Male, age 72, unknown 61.2
2503 Female, age 72, unknown 61.1
1865 Male, age 51, unknown 60.8
2823 Male, age 76, right hemisphere 60.5
2588 Male, age 74, left hemisphere 60.1
Substantia nigra
nTPM: 59.8
2665 Male, age 74, both hemispheres 64.1
2590 Female, age 75, unknown 61.8
1941 Male, age 53, unknown 61.6
1916 Female, age 42, unknown 60.6
2699 Male, age 18, unknown 60.2
2409 Female, age 72, unknown 58.9
1851 Male, age 51, unknown 58.4
2241 Male, age 72, unknown 58.4
2583 Male, age 75, right hemisphere 57.9
1889 Female, age 72, unknown 56.0
Superior colliculus
nTPM: 57.6
1913 Female, age 42, unknown 62.5
2664 Male, age 75, both hemispheres 60.8
1995 Male, age 72, unknown 59.5
1839 Male, age 51, unknown 58.4
2587 Male, age 74, left hemisphere 58.2
2668 Female, age 75, unknown 57.5
2087 Female, age 72, unknown 56.6
1796 Male, age 53, unknown 56.3
2261 Male, age 18, unknown 54.6
1895 Male, age 76, right hemisphere 52.1
Ventral tegmental area
nTPM: 58.5
2223 Female, age 72, unknown 63.4
2021 Male, age 53, unknown 58.8
1942 Male, age 51, unknown 58.7
2218 Male, age 76, both hemispheres 58.0
2410 Female, age 72, unknown 56.9
1915 Female, age 42, unknown 55.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 55.1
Samples: 139

Max nTPM: 96.0
Min nTPM: 31.0
Std nTPM: 12.8
Median nTPM: 52.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 96.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 94.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 94.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 89.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 84.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 82.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 80.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 79.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 76.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 75.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 75.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 74.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 74.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 73.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 73.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 72.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 71.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 69.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 69.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 69.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 68.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 67.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 64.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 63.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 63.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 63.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 62.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 62.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 61.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 61.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 60.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 59.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 59.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 59.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 59.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 58.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 58.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 57.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 57.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 57.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 57.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 56.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 56.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 55.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 55.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 54.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 54.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 54.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 54.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 54.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 54.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 54.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 53.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 53.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 53.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 53.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 53.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 52.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 52.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 52.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 52.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 51.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 51.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 51.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 51.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 51.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 51.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 51.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 50.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 50.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 50.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 49.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 49.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 48.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 48.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 48.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 47.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 47.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 47.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 47.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 47.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 47.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 47.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 47.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 47.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 46.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 46.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 46.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 45.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 45.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 45.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 45.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 45.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 45.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 45.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 44.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 44.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 44.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 44.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 44.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 44.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 43.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 43.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 43.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 43.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 43.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 43.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 42.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 42.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 42.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 41.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 41.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 40.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 40.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 40.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 39.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 38.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 38.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 38.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 38.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 37.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 34.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 34.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 160.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 160.2
FF:10158-103A5 76 years, female 160.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 185.6
Pig sample Sample description nTPM
Midbrain
nTPM: 184.6
Samples: 4

Max nTPM: 264.3
Min nTPM: 143.0
Sample A Female 264.3
Sample B Female 179.5
Sample C Male 151.6
Sample D Male 143.0
Periaqueductal gray
nTPM: 163.9
Samples: 3

Max nTPM: 165.5
Min nTPM: 162.5
Sample B Female 162.5
Sample C Male 165.5
Sample D Male 163.8
Substantia nigra
nTPM: 185.6
Samples: 4

Max nTPM: 221.5
Min nTPM: 161.1
Sample A Female 187.4
Sample B Female 161.1
Sample C Male 172.5
Sample D Male 221.5
Superior colliculi
nTPM: 181.9
Samples: 4

Max nTPM: 205.0
Min nTPM: 137.8
Sample A Female 205.0
Sample B Female 137.8
Sample C Male 183.9
Sample D Male 200.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 44.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 44.0
Samples: 4

Max nTPM: 45.1
Min nTPM: 43.0
Sample A Male 43.6
Sample B Male 45.1
Sample C Female 44.4
Sample D Female 43.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.8
69289333 Antisense, RP_050407_03_A03, Mouse strain C57BL/6J (56 days, male) 3.8

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