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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:387.0 nTPM
HPA:387.0 nTPM
FANTOM5:297.8 Scaled Tags Per Million
Pig:120.8 nTPM
Allen mouse:6.9 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 387.0
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 340.2
2188 Female, age 91, both hemispheres 348.4
2301 Female, age 85, both hemispheres 340.5
2090 Male, age 80, both hemispheres 339.1
1984 Male, age 76, both hemispheres 332.7
Dorsal cochlear nucleus
nTPM: 339.5
2187 Female, age 91, both hemispheres 354.7
2802 Male, age 74, right hemisphere 349.4
2370 Male, age 61, both hemispheres 336.7
2058 Male, age 76, both hemispheres 335.0
2378 Male, age 80, both hemispheres 321.8
Dorsal tegmental nucleus
nTPM: 350.8
2083 Male, age 80, both hemispheres 371.7
2326 Male, age 74, both hemispheres 347.2
2358 Male, age 61, both hemispheres 343.0
1936 Male, age 76, left hemisphere 341.3
Dorsolateral tegmental area
nTPM: 357.8
2360 Male, age 74, both hemispheres 382.0
2654 Male, age 80, both hemispheres 366.6
2141 Male, age 76, both hemispheres 356.3
2751 Female, age 85, both hemispheres 351.4
2337 Male, age 61, both hemispheres 332.7
Kolliker-Fuse nucleus
nTPM: 361.5
2163 Male, age 80, both hemispheres 379.4
2793 Female, age 91, left hemisphere 358.2
2315 Male, age 76, right hemisphere 346.9
Lateral lemniscal nuclei
nTPM: 360.7
2169 Male, age 76, both hemispheres 408.9
2746 Female, age 85, left hemisphere 376.7
2453 Male, age 74, right hemisphere 347.8
2036 Male, age 80, both hemispheres 345.2
2320 Female, age 91, left hemisphere 324.9
Lateral parabrachial nucleus
nTPM: 356.1
2139 Female, age 85, right hemisphere 402.1
2013 Male, age 80, both hemispheres 353.6
2790 Male, age 61, both hemispheres 335.8
2792 Male, age 76, both hemispheres 332.8
Lateral vestibular nucleus
nTPM: 364.1
2184 Male, age 76, both hemispheres 371.1
2311 Male, age 80, both hemispheres 357.2
Locus coeruleus
nTPM: 380.7
2123 Female, age 91, both hemispheres 424.7
2014 Male, age 55, unknown 390.8
2720 Male, age 74, both hemispheres 385.8
2317 Female, age 72, unknown 371.4
2788 Male, age 74, unknown 367.1
1980 Male, age 76, both hemispheres 366.9
2162 Male, age 80, both hemispheres 358.3
Medial olivary nucleus
nTPM: 334.1
2851 Male, age 80, both hemispheres 342.5
2138 Female, age 91, both hemispheres 340.2
1943 Male, age 61, both hemispheres 329.1
1962 Male, age 76, both hemispheres 324.5
Medial parabrachial nucleus
nTPM: 359.2
2170 Female, age 91, both hemispheres 378.6
2854 Male, age 80, both hemispheres 377.6
2156 Male, age 61, both hemispheres 353.3
2786 Male, age 76, both hemispheres 349.9
2463 Female, age 85, right hemisphere 336.6
Medial periolivary nuclei
nTPM: 360.3
2171 Female, age 85, both hemispheres 415.9
2063 Male, age 76, both hemispheres 386.8
2791 Male, age 74, right hemisphere 347.8
2458 Female, age 91, both hemispheres 325.9
2081 Male, age 80, both hemispheres 325.3
Motor facial nucleus
nTPM: 363.9
2062 Male, age 76, both hemispheres 399.9
2697 Female, age 85, both hemispheres 378.6
2365 Male, age 74, right hemisphere 361.7
2327 Male, age 80, both hemispheres 350.6
2795 Female, age 91, both hemispheres 348.2
2126 Male, age 61, both hemispheres 344.7
Motor trigeminal nucleus
nTPM: 348.8
2079 Male, age 80, both hemispheres 365.9
2309 Male, age 76, both hemispheres 356.6
2335 Male, age 61, both hemispheres 355.5
2560 Male, age 74, both hemispheres 340.1
2321 Female, age 91, both hemispheres 326.0
Nuclei of the trapezoid body
nTPM: 372.1
1983 Male, age 76, both hemispheres 400.2
2159 Male, age 61, both hemispheres 396.4
2735 Female, age 85, both hemispheres 391.6
2166 Male, age 80, both hemispheres 349.2
2368 Female, age 91, both hemispheres 323.0
Paramedian reticular nucleus
nTPM: 367.0
2050 Female, age 85, both hemispheres 409.3
2313 Male, age 61, both hemispheres 360.0
2057 Male, age 80, both hemispheres 359.7
2052 Male, age 76, both hemispheres 339.0
Pontine nuclei
nTPM: 380.0
2787 Female, age 85, both hemispheres 471.1
1863 Male, age 55, unknown 416.7
2727 Male, age 61, right hemisphere 397.5
2109 Female, age 72, unknown 378.6
1968 Male, age 76, left hemisphere 374.0
2454 Male, age 74, left hemisphere 335.3
2115 Male, age 80, left hemisphere 333.9
2319 Female, age 91, both hemispheres 332.8
Pontine raphe nucleus
nTPM: 376.1
2122 Female, age 85, midline 394.1
2853 Male, age 76, midline 358.0
Posteroventral cochlear nucleus
nTPM: 344.6
2752 Female, age 85, both hemispheres 379.0
2070 Male, age 76, both hemispheres 351.9
2341 Male, age 80, both hemispheres 333.5
2371 Male, age 61, both hemispheres 332.9
2135 Female, age 91, both hemispheres 325.6
Principal sensory trigeminal nucleus
nTPM: 368.9
2158 Male, age 61, both hemispheres 408.1
2008 Male, age 80, left hemisphere 373.4
2324 Male, age 76, both hemispheres 365.1
2367 Female, age 91, left hemisphere 328.9
Reticular pontine nucleus, caudal
nTPM: 358.8
2092 Male, age 76, both hemispheres 388.8
2332 Male, age 80, right hemisphere 361.5
2559 Male, age 74, both hemispheres 343.6
2457 Female, age 91, both hemispheres 341.4
Reticular pontine nucleus, oral
nTPM: 353.9
2012 Female, age 85, both hemispheres 385.0
1939 Male, age 80, both hemispheres 360.6
2167 Male, age 76, both hemispheres 357.1
2366 Female, age 91, both hemispheres 338.2
2361 Male, age 74, both hemispheres 328.9
Reticulotegmental nucleus
nTPM: 354.4
2325 Male, age 76, both hemispheres 377.0
2322 Female, age 91, both hemispheres 352.9
2333 Male, age 80, both hemispheres 347.1
2452 Male, age 74, both hemispheres 340.7
Spinal trigeminal nucleus, oral
nTPM: 358.6
2737 Female, age 85, both hemispheres 372.4
2164 Male, age 80, both hemispheres 364.4
1978 Male, age 76, both hemispheres 339.0
Subcoeruleus area
nTPM: 359.3
2323 Female, age 91, left hemisphere 387.4
1958 Male, age 80, both hemispheres 382.6
2089 Male, age 76, left hemisphere 354.0
2451 Male, age 74, both hemispheres 338.0
2369 Female, age 85, left hemisphere 334.5
Superior olive
nTPM: 358.4
1875 Female, age 85, both hemispheres 396.7
2020 Male, age 76, both hemispheres 370.1
2364 Male, age 74, right hemisphere 346.6
2329 Male, age 80, right hemisphere 344.3
2561 Female, age 91, both hemispheres 334.4
Superior vestibular nucleus
nTPM: 387.0
2383 Male, age 74, both hemispheres 439.6
2015 Male, age 80, both hemispheres 376.1
2061 Male, age 76, both hemispheres 345.2
Ventral periolivary nuclei
nTPM: 376.1
2130 Female, age 85, both hemispheres 406.2
2165 Male, age 80, both hemispheres 395.6
2023 Male, age 76, both hemispheres 362.9
2794 Female, age 91, left hemisphere 339.9
Ventrolateral tegmental area, A5 NE cell group
nTPM: 352.9
2840 Female, age 85, both hemispheres 398.2
1959 Male, age 76, both hemispheres 364.0
2449 Male, age 74, both hemispheres 362.2
2161 Male, age 80, both hemispheres 341.4
2359 Male, age 61, both hemispheres 338.7
2456 Female, age 91, both hemispheres 312.9

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 297.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 297.8
FF:10182-103D2 60 years, female 379.6
FF:10165-103B3 76 years, female 215.9
Pons
Scaled Tags Per Million: 244.7
FF:10033-101E6 18-54 years, mixed 244.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 120.8
Pig sample Sample description nTPM
Pons
nTPM: 120.8
Samples: 4

Max nTPM: 158.9
Min nTPM: 75.9
Sample A Female 158.9
Sample B Female 75.9
Sample C Male 99.5
Sample D Male 148.9

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.9
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 6.9
76115740 Antisense, RP_060620_02_C08, Mouse strain C57BL/6J (56 days, male) 8.0
69817270 Antisense, RP_050510_03_A05, Mouse strain C57BL/6J (56 days, male) 5.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.