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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:157.1 nTPM
HPA:157.1 nTPM
GTEx:155.8 nTPM
FANTOM5:87.0 Scaled Tags Per Million
Pig:46.5 nTPM
Mouse:67.0 nTPM
Allen mouse:4.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 157.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 157.1
2666 Male, age 74, left hemisphere 186.1
2586 Male, age 75, left hemisphere 185.3
2019 Male, age 18, unknown 168.4
1827 Male, age 72, unknown 156.7
1830 Male, age 51, unknown 155.8
2828 Female, age 72, unknown 155.6
2411 Female, age 72, unknown 151.4
1833 Male, age 53, unknown 142.0
1870 Female, age 42, unknown 135.0
2219 Male, age 76, both hemispheres 134.4
Dorsal raphe nucleus
nTPM: 130.4
2016 Female, age 72, unknown 139.6
1828 Male, age 53, unknown 134.2
2047 Male, age 72, unknown 130.0
2750 Male, age 76, both hemispheres 125.1
2298 Female, age 72, unknown 123.3
Inferior colliculus
nTPM: 138.2
2849 Male, age 72, unknown 141.6
1890 Male, age 53, unknown 140.9
1848 Female, age 42, unknown 136.5
2097 Female, age 72, unknown 133.8
Median raphe nucleus
nTPM: 125.5
2220 Male, age 76, midline 125.5
Pedunculopontine tegmental nucleus
nTPM: 135.0
2334 Male, age 80, both hemispheres 137.8
1921 Female, age 85, both hemispheres 134.2
2338 Male, age 61, both hemispheres 132.9
Periaquaductal grey, anterior
nTPM: 145.4
1795 Male, age 51, unknown 149.0
1947 Male, age 18, unknown 144.2
2502 Female, age 75, unknown 143.1
Periaquaductal grey, dorsal
nTPM: 137.6
2464 Female, age 72, unknown 144.6
1831 Male, age 72, unknown 140.2
1840 Male, age 53, unknown 133.1
2850 Male, age 76, both hemispheres 132.7
Periaquaductal grey, lateral
nTPM: 132.6
2053 Male, age 18, unknown 141.1
2140 Male, age 76, both hemispheres 128.7
2272 Male, age 74, both hemispheres 128.0
Pretectal area
nTPM: 153.1
2007 Male, age 72, unknown 187.3
1944 Female, age 72, unknown 176.5
1815 Male, age 53, unknown 175.2
1816 Male, age 51, unknown 171.9
2407 Male, age 75, both hemispheres 165.5
1817 Female, age 42, unknown 161.6
2316 Male, age 76, right hemisphere 136.2
2667 Female, age 75, unknown 131.0
2825 Male, age 18, unknown 127.6
2224 Female, age 72, unknown 126.9
2273 Male, age 74, both hemispheres 124.2
Red nucleus
nTPM: 154.6
2588 Male, age 74, left hemisphere 186.9
2785 Male, age 18, unknown 178.4
2584 Male, age 75, left hemisphere 177.0
2823 Male, age 76, right hemisphere 158.7
1865 Male, age 51, unknown 155.8
2725 Female, age 75, unknown 149.1
2503 Female, age 72, unknown 146.4
2769 Male, age 72, unknown 143.3
1954 Female, age 42, unknown 143.1
2227 Male, age 72, unknown 141.0
1904 Male, age 53, unknown 139.0
1821 Female, age 72, unknown 136.8
Substantia nigra
nTPM: 147.8
2583 Male, age 75, right hemisphere 165.1
2590 Female, age 75, unknown 163.5
2665 Male, age 74, both hemispheres 163.2
1941 Male, age 53, unknown 155.7
1889 Female, age 72, unknown 154.8
2409 Female, age 72, unknown 145.1
1851 Male, age 51, unknown 138.8
2241 Male, age 72, unknown 132.1
1916 Female, age 42, unknown 130.1
2699 Male, age 18, unknown 129.2
Superior colliculus
nTPM: 155.0
2668 Female, age 75, unknown 168.5
2087 Female, age 72, unknown 165.4
2664 Male, age 75, both hemispheres 163.2
2261 Male, age 18, unknown 158.3
1913 Female, age 42, unknown 156.4
1995 Male, age 72, unknown 155.8
1796 Male, age 53, unknown 151.0
2587 Male, age 74, left hemisphere 145.8
1895 Male, age 76, right hemisphere 143.2
1839 Male, age 51, unknown 142.1
Ventral tegmental area
nTPM: 135.8
2410 Female, age 72, unknown 160.3
2021 Male, age 53, unknown 135.1
1942 Male, age 51, unknown 132.5
2218 Male, age 76, both hemispheres 132.4
2223 Female, age 72, unknown 129.7
1915 Female, age 42, unknown 125.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 155.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 155.8
Samples: 139

Max nTPM: 265.1
Min nTPM: 77.4
Std nTPM: 37.1
Median nTPM: 146.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 265.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 256.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 250.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 248.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 241.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 239.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 233.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 222.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 221.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 220.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 218.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 215.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 207.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 206.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 205.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 205.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 204.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 201.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 201.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 201.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 201.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 199.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 198.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 198.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 195.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 195.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 189.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 188.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 187.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 185.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 182.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 179.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 179.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 178.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 178.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 173.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 172.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 170.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 170.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 170.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 169.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 168.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 168.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 167.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 166.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 166.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 165.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 164.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 164.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 164.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 163.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 162.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 161.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 161.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 160.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 160.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 160.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 158.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 154.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 154.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 154.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 153.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 153.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 151.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 151.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 148.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 147.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 147.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 147.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 146.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 146.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 145.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 145.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 145.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 145.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 144.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 144.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 143.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 143.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 141.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 139.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 139.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 139.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 138.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 137.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 137.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 136.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 136.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 136.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 134.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 134.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 134.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 134.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 134.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 133.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 132.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 131.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 131.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 130.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 130.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 130.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 129.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 128.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 127.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 126.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 126.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 125.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 125.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 125.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 125.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 125.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 125.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 124.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 124.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 123.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 123.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 122.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 121.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 121.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 121.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 120.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 120.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 120.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 118.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 118.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 116.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 115.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 113.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 112.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 112.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 110.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 110.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 109.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 106.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 104.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 101.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 100.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 95.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 77.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 87.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 87.0
FF:10158-103A5 76 years, female 87.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 46.5
Pig sample Sample description nTPM
Midbrain
nTPM: 44.5
Samples: 4

Max nTPM: 61.0
Min nTPM: 31.1
Sample A Female 33.7
Sample B Female 31.1
Sample C Male 61.0
Sample D Male 52.3
Periaqueductal gray
nTPM: 34.0
Samples: 3

Max nTPM: 40.5
Min nTPM: 30.0
Sample B Female 31.4
Sample C Male 40.5
Sample D Male 30.0
Substantia nigra
nTPM: 39.9
Samples: 4

Max nTPM: 44.2
Min nTPM: 35.8
Sample A Female 39.3
Sample B Female 40.2
Sample C Male 44.2
Sample D Male 35.8
Superior colliculi
nTPM: 46.6
Samples: 4

Max nTPM: 52.8
Min nTPM: 41.9
Sample A Female 41.9
Sample B Female 43.2
Sample C Male 48.3
Sample D Male 52.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 67.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 67.0
Samples: 4

Max nTPM: 69.8
Min nTPM: 64.0
Sample A Male 64.0
Sample B Male 65.3
Sample C Female 69.8
Sample D Female 69.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.5
68844235 Antisense, RP_050222_01_B09, Mouse strain C57BL/6J (56 days, male) 4.5

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